Aging and disease

Transplantation of ACE2^- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia

Zikuan Leng, Rongjia Zhu, Wei Hou, Yingmei Feng, Yanlei Yang, Qin Han, Guangliang Shan, Fanyan Meng, Dongshu Du, Shihua Wang, Junfen Fan, Wenjing Wang, Luchan Deng, Hongbo Shi, Hongjun Li, Zhongjie Hu, Fengchun Zhang, Jinming Gao, Hongjian Liu, Xiaoxia Li, Yangyang Zhao, Kan Yin, Xijing He, Zhengchao Gao, Yibin Wang, Bo Yang, Ronghua Jin, Ilia Stambler, Lee Wei Lim, Huanxing Su, Alexey Moskalev, Antonio Cano, Sasanka Chakrabarti, Kyung-Jin Min, Georgina Ellison-Hughes, Calogero Caruso, Kunlin Jin, Robert Chunhua Zhao

Aging and disease 2020, 11 (2): 216-228. DOI: 10.14336/AD.2020.0228

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The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases

Wenjun Tu, Hong Wang, Song Li, Qiang Liu, Hong Sha

Aging and disease 2019, 10 (3): 637-651. DOI: 10.14336/AD.2018.0513

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Emerging Anti-Aging Strategies - Scientific Basis and Efficacy

Ashok K. Shetty, Maheedhar Kodali, Raghavendra Upadhya, Leelavathi N. Madhu

Aging and disease 2018, 9 (6): 1165-1184. DOI: 10.14336/AD.2018.1026

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Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept

Hae Young Chung, Dae Hyun Kim, Eun Kyeong Lee, Ki Wung Chung, Sangwoon Chung, Bonggi Lee, Arnold Y. Seo, Jae Heun Chung, Young Suk Jung, Eunok Im, Jaewon Lee, Nam Deuk Kim, Yeon Ja Choi, Dong Soon Im, Byung Pal Yu

Aging and disease 2019, 10 (2): 367-382. DOI: 10.14336/AD.2018.0324

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Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic

Ping Liu, Haiping Zhao, Yumin Luo

Aging and disease 2017, 8 (6): 868-886. DOI: 10.14336/AD.2017.0816

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TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?

Mahesh Kandasamy, Muthuswamy Anusuyadevi, Kiera M Aigner, Michael S Unger, Kathrin M Kniewallner, Diana M Bessa de Sousa, Barbara Altendorfer, Heike Mrowetz, Ulrich Bogdahn, Ludwig Aigner

Aging and disease 2020, 11 (4): 828-850. DOI: 10.14336/AD.2020.0222

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Parkinson Disease and Orthostatic Hypotension in the Elderly: Recognition and Management of Risk Factors for Falls

Peter A LeWitt, Steve Kymes, Robert A Hauser

Aging and disease 2020, 11 (3): 679-691. DOI: 10.14336/AD.2019.0805

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Dizziness and Imbalance in the Elderly: Age-related Decline in the Vestibular System

Shinichi Iwasaki, Tatsuya Yamasoba

Aging and disease 2015, 6 (1): 38-47. DOI: 10.14336/AD.2014.0128

[457KB]（5834）

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mHealth For Aging China: Opportunities and Challenges

Jing Sun, Yutao Guo, Xiaoning Wang, Qiang Zeng

Aging and disease 2016, 7 (1): 53-67. DOI: 10.14336/AD.2015.1011

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Pyroptosis Plays a Role in Osteoarthritis

Senbo An, Huiyu Hu, Yusheng Li, Yihe Hu

Aging and disease 2020, 11 (5): 1146-1157. DOI: 10.14336/AD.2019.1127

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Gut Microbiome and Osteoporosis

Kai Ding, Fei Hua, Wenge Ding

Aging and disease 2020, 11 (2): 438-447. DOI: 10.14336/AD.2019.0523

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Exercise Programs for Muscle Mass, Muscle Strength and Physical Performance in Older Adults with Sarcopenia: A Systematic Review and Meta-Analysis

Wangxiao Bao, Yun Sun, Tianfang Zhang, Liliang Zou, Xiaohong Wu, Daming Wang, Zuobing Chen

Aging and disease 2020, 11 (4): 863-873. DOI: 10.14336/AD.2019.1012

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Metabolic Syndrome, Aging and Involvement of Oxidative Stress

Francesca Bonomini, Luigi Fabrizio Rodella, Rita Rezzani

Aging and disease 2015, 6 (2): 109-120. DOI: 10.14336/AD.2014.0305

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Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia

Ashok K Shetty

Aging and disease 2020, 11 (2): 462-464. DOI: 10.14336/AD.2020.0301

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Reactive Astrocytes in Neurodegenerative Diseases

Kunyu Li, Jiatong Li, Jialin Zheng, Song Qin

Aging and disease 2019, 10 (3): 664-675. DOI: 10.14336/AD.2018.0720

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Pyroptosis in Liver Disease: New Insights into Disease Mechanisms

Jiali Wu, Su Lin, Bo Wan, Bharat Velani, Yueyong Zhu

Aging and disease 2019, 10 (5): 1094-1108. DOI: 10.14336/AD.2019.0116

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Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease

Aida Adlimoghaddam, Gary G Odero, Gordon Glazner, R. Scott Turner, Benedict C Albensi

Aging and disease 2021, 12 (2): 441-465. DOI: 10.14336/AD.2020.0910

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The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

Aging and disease 2015, 6 (5): 331-341. DOI: 10.14336/AD.2015.0825

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Multi-organ Dysfunction in Patients with COVID-19: A Systematic Review and Meta-analysis

Ting Wu, Zhihong Zuo, Shuntong Kang, Liping Jiang, Xuan Luo, Zanxian Xia, Jing Liu, Xiaojuan Xiao, Mao Ye, Meichun Deng

Aging and disease 2020, 11 (4): 874-894. DOI: 10.14336/AD.2020.0520

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Lycium Barbarum: A Traditional Chinese Herb and A Promising Anti-Aging Agent

Yanjie Gao, Yifo Wei, Yuqing Wang, Fang Gao, Zhigang Chen

Aging and disease 2017, 8 (6): 778-791. DOI: 10.14336/AD.2017.0725

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Phenylketonuria Pathophysiology: on the Role of Metabolic Alterations

Aging and disease 2015, 6 (5): 390-399. DOI: 10.14336/AD.2015.0827

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The Potential Markers of Circulating microRNAs and long non-coding RNAs in Alzheimer's Disease

Yanfang Zhao, Yuan Zhang, Lei Zhang, Yanhan Dong, Hongfang Ji, Liang Shen

Aging and disease 2019, 10 (6): 1293-1301. DOI: 10.14336/AD.2018.1105

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Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer’s Disease

Ashok K. Shetty, Raghavendra Upadhya, Leelavathi N. Madhu, Maheedhar Kodali

Aging and disease 2019, 10 (2): 470-482. DOI: 10.14336/AD.2019.0330

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Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause

Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu

Aging and disease 2024, 15 (2): 445-448. DOI: 10.14336/AD.2023.0707-1

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Comorbid Chronic Diseases are Strongly Correlated with Disease Severity among COVID-19 Patients: A Systematic Review and Meta-Analysis

Hong Liu, Shiyan Chen, Min Liu, Hao Nie, Hongyun Lu

Aging and disease 2020, 11 (3): 668-678. DOI: 10.14336/AD.2020.0502

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Nitrate and Nitrite in Health and Disease

Linsha Ma, Liang Hu, Xiaoyu Feng, Songlin Wang

Aging and disease 2018, 9 (5): 938-945. DOI: 10.14336/AD.2017.1207

[546KB]（4695）

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Glycation Damage: A Possible Hub for Major Pathophysiological Disorders and Aging

Maxime Fournet, Frédéric Bonté, Alexis Desmoulière

Aging and disease 2018, 9 (5): 880-900. DOI: 10.14336/AD.2017.1121

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The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks

Jan R. Aunan, William C Cho, Kjetil Søreide

Aging and disease 2017, 8 (5): 628-642. DOI: 10.14336/AD.2017.0103

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Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience

Alexey Moskalev, Ilia Stambler, Calogero Caruso

Aging and disease 2020, 11 (6): 1363-1373. DOI: 10.14336/AD.2020.0603

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Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia

Yuxiao Liao, Zhao Peng, Liangkai Chen, Yan Zhang, Qian Cheng, Andreas K. Nüssler, Wei Bao, Liegang Liu, Wei Yang

Aging and disease 2019, 10 (1): 157-173. DOI: 10.14336/AD.2018.0325

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The Critical Need to Promote Research of Aging and Aging-related Diseases to Improve Health and Longevity of the Elderly Population

Kunlin Jin, James W. Simpkins, Xunming Ji, Miriam Leis, Ilia Stambler

Aging and disease 2015, 6 (1): 1-5. DOI: 10.14336/AD.2014.1210

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Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling

Xu-Xu Deng, Shan-Shan Li, Feng-Yan Sun

Aging and disease 2019, 10 (4): 807-817. DOI: 10.14336/AD.2018.0728

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Dopamine Receptors and Neurodegeneration

Aging and disease 2015, 6 (5): 349-368. DOI: 10.14336/AD.2015.0330

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Mitochondria in Ischemic Stroke: New Insight and Implications

Fan Liu, Jianfei Lu, Anatol Manaenko, Junjia Tang, Qin Hu

Aging and disease 2018, 9 (5): 924-937. DOI: 10.14336/AD.2017.1126

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Emerging Roles of Ganoderma Lucidum in Anti-Aging

Jue Wang, Bin Cao, Haiping Zhao, Juan Feng

Aging and disease 2017, 8 (6): 691-707. DOI: 10.14336/AD.2017.0410

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The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review

Wei Liang, Xiaobo Huang, Wenqiang Chen

Aging and disease 2017, 8 (6): 850-867. DOI: 10.14336/AD.2017.0829

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Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect

Tia R. Tidwell, Kjetil Søreide, Hanne R. Hagland

Aging and disease 2017, 8 (5): 662-676. DOI: 10.14336/AD.2017.0713

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Hypoglycemia in Older People - A Less Well Recognized Risk Factor for Frailty

Ahmed H Abdelhafiz, Leocadio Rodríguez-Mañas, John E. Morley, Alan J Sinclair

Aging and disease 2015, 6 (2): 156-167. DOI: 10.14336/AD.2014.0330

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Mechanism of Ferroptosis: A Potential Target for Cardiovascular Diseases Treatment

Jie Ju, Ya-nan Song, Kun Wang

Aging and disease 2021, 12 (1): 261-276. DOI: 10.14336/AD.2020.0323

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Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: An Update

Feng Zhang, Long Niu, Xinyao Liu, Yufei Liu, Song Li, Huan Yu, Weidong Le

Aging and disease 2020, 11 (2): 315-326. DOI: 10.14336/AD.2019.0324

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