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Aging and disease

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Total 40 results are found
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
2024, 15 (2): 445-448 | DOI: 10.14336/AD.2023.0707-1
PDF (599KB)
Supplement

1. Supplementary data.pdf (2374KB)

Extracellular Vesicles for the Diagnosis and Treatment of Parkinson’s Disease
Raghavendra Upadhya, Ashok K Shetty
2021, 12 (6): 1438-1450 | DOI: 10.14336/AD.2021.0516
PDF (843KB)
Promising Intervention Approaches to Potentially Resolve Neuroinflammation And Steroid Hormones Alterations in Alzheimer’s Disease and Its Neuropsychiatric Symptoms
Catia Scassellati, Antonio Carlo Galoforo, Ciro Esposito, Miriam Ciani, Giovanni Ricevuti, Cristian Bonvicini
2021, 12 (5): 1337-1357 | DOI: 10.14336/AD.2021.0122
PDF (1633KB)
Supplement

1. Supplementary data.pdf (290KB)

The Role of SGLT2 Inhibitors in Vascular Aging
Le Liu, Yu-Qing Ni, Jun-Kun Zhan, You-Shuo Liu
2021, 12 (5): 1323-1336 | DOI: 10.14336/AD.2020.1229
PDF (737KB)
DeepMAge: A Methylation Aging Clock Developed with Deep Learning
Fedor Galkin, Polina Mamoshina, Kirill Kochetov, Denis Sidorenko, Alex Zhavoronkov
2021, 12 (5): 1252-1262 | DOI: 10.14336/AD.2020.1202
PDF (742KB)
Supplement

1. Supplementary data.pdf (2088KB)

An Update on Medical and Surgical Treatments of Parkinson’s Disease
Dipali Nemade, Thyagarajan Subramanian, Vikram Shivkumar
2021, 12 (4): 1021-1035 | DOI: 10.14336/AD.2020.1225
PDF (535KB)
Acute Stroke Management: Overview and Recent Updates
Hollist Mary, Morgan Larry, Cabatbat Rainier, Au Katherine, F. Kirmani Maaida, F. Kirmani Batool
2021, 12 (4): 1000-1009 | DOI: 10.14336/AD.2021.0311
PDF (583KB)
Cellular Senescence in Cardiovascular Diseases: A Systematic Review
Can Hu, Xin Zhang, Teng Teng, Zhen-Guo Ma, Qi-Zhu Tang
2022, 13 (1): 103-128 | DOI: 10.14336/AD.2021.0927
PDF (883KB)
MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis
Yanhui Cui, Xueqin Wang, Fengyu Lin, Wen Li, Yuhao Zhao, Fei Zhu, Hang Yang, Mingjun Rao, Yi li, Huaying Liang, Minhui Dai, Ben Liu, Lingli Chen, Duoduo Han, Rongli Lu, Wenzhong Peng, Yan Zhang, Chao Song, Yanwei Luo, Pinhua Pan
2022, 13 (3): 899-909 | DOI: 10.14336/AD.2021.1023
PDF (1271KB)
Supplement

1. Supplementary data.pdf (144KB)

SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases
Zhenyang Guo, Peng Li, Junbo Ge, Hua Li
2022, 13 (6): 1787-1822 | DOI: 10.14336/AD.2022.0413
PDF (2013KB)
Supplement

1. Supplementary data.pdf (527KB)

Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration
Hongliang Yu, Xudong Yang, Xian Xiao, Meiqian Xu, Yanlei Yang, Chunling Xue, Xuechun Li, Shihua Wang, Robert Chunhua Zhao
2021, 12 (6): 1423-1437 | DOI: 10.14336/AD.2021.0601
PDF (1572KB)
Supplement

1. Supplementary data.pdf (100KB)

Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives
Juan Liu, Yuzhu Tan, Hao Cheng, Dandan Zhang, Wuwen Feng, Cheng Peng
2022, 13 (4): 1106-1126 | DOI: 10.14336/AD.2022.0104
PDF (1455KB)
CD36 Signaling in Diabetic Cardiomyopathy
Xudong Zhang, Jiahui Fan, Huaping Li, Chen Chen, Yan Wang
2021, 12 (3): 826-840 | DOI: 10.14336/AD.2020.1217
PDF (869KB)
Exercise in Aging: Be Balanced
Joanna Gronek, Michał Boraczyński, Piotr Gronek, Dariusz Wieliński, Jacek Tarnas, Sławomir Marszałek, Yi-Yuan Tang
2021, 12 (5): 1140-1149 | DOI: 10.14336/AD.2021.0107
PDF (639KB)
Intrinsic Capacity in Older Adults: Recent Advances
Yaru Zhou, Lina Ma
2022, 13 (2): 353-359 | DOI: 10.14336/AD.2021.0818
PDF (361KB)
Effects of Pyruvate Administration on Mitochondrial Enzymes, Neurological Behaviors, and Neurodegeneration after Traumatic Brain Injury
Prasanth S Ariyannur, Guoqiang Xing, Erin S Barry, Brandi Benford, Neil E Grunberg, Pushpa Sharma
2021, 12 (4): 983-999 | DOI: 10.14336/AD.2020.1015
PDF (1325KB)
Premature Senescence of T-cells Favors Bone Loss During Osteolytic Diseases. A New Concern in the Osteoimmunology Arena
Luis González-Osuna, Alfredo Sierra-Cristancho, Carolina Rojas, Emilio A Cafferata, Samanta Melgar-Rodríguez, Angélica M Cárdenas, Rolando Vernal
2021, 12 (5): 1150-1161 | DOI: 10.14336/AD.2021.0110
PDF (1165KB)
Contrasting Metabolic Insufficiency in Aging and Dementia
Dennis A Turner
2021, 12 (4): 1081-1096 | DOI: 10.14336/AD.2021.0104
PDF (624KB)
Deficiency of Endothelial Nitric Oxide Synthase (eNOS) Exacerbates Brain Damage and Cognitive Deficit in A Mouse Model of Vascular Dementia
Lulu An, Yi Shen, Michael Chopp, Alex Zacharek, Poornima Venkat, Zhili Chen, Wei Li, Yu Qian, Julie Landschoot-Ward, Jieli Chen
2021, 12 (3): 732-746 | DOI: 10.14336/AD.2020.0523
PDF (1732KB)
The Molecular Regulation in the Pathophysiology in Ovarian Aging
Chia-Jung Li, Li-Te Lin, Hsiao-Wen Tsai, Chyi-Uei Chern, Zhi-Hong Wen, Peng-Hui Wang, Kuan-Hao Tsui
2021, 12 (3): 934-949 | DOI: 10.14336/AD.2020.1113
PDF (767KB)
Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson’s Disease
Loredana Leggio, Greta Paternò, Silvia Vivarelli, Giovanna G Falzone, Carmela Giachino, Bianca Marchetti, Nunzio Iraci
2021, 12 (6): 1494-1515 | DOI: 10.14336/AD.2021.0527
PDF (1170KB)
Hypoxia and the Aging Cardiovascular System
Antoine Raberin, Johannes Burtscher, Martin Burtscher, Grégoire P. Millet
2023, 14 (6): 2051-2070 | DOI: 10.14336/AD.2023.0424
PDF (1003KB)
Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases
Ziying Jiang, Xi Yin, Miao Wang, Tong Chen, Yuanyuan Wang, Zhongbao Gao, Zhenfu Wang
2022, 13 (4): 1146-1165 | DOI: 10.14336/AD.2021.1217
PDF (808KB)
Delineating the Role of Mitophagy Inducers for Alzheimer Disease Patients
Wen-Wen Wang, Ruiyu Han, Hai-Jun He, Zhen Wang, Xiao-Qian Luan, Jia Li, Liang Feng, Si-Yan Chen, Yahyah Aman, Cheng-Long Xie
2021, 12 (3): 852-867 | DOI: 10.14336/AD.2020.0913
PDF (918KB)
ACE2 and COVID-19 Susceptibility and Severity
Ming Zheng
2022, 13 (2): 360-372 | DOI: 10.14336/AD.2021.0805
PDF (1806KB)
tRNA-derived fragments as New Hallmarks of Aging and Age-related Diseases
Ya Yuan, Jiamei Li, Zhi He, Xiaolan Fan, Xueping Mao, Mingyao Yang, Deying Yang
2021, 12 (5): 1304-1322 | DOI: 10.14336/AD.2021.0115
PDF (937KB)
MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease
Chunling Xue, Xuechun Li, Li Ba, Mingjia Zhang, Ying Yang, Yang Gao, Zhao Sun, Qin Han, Robert Chunhua Zhao
2021, 12 (5): 1211-1222 | DOI: 10.14336/AD.2020.1221
PDF (1718KB)
Super-Refractory Status Epilepticus: Prognosis and Recent Advances in Management
Batool F Kirmani, Katherine Au, Lena Ayari, Marita John, Padmashri Shetty, Robert J Delorenzo
2021, 12 (4): 1097-1119 | DOI: 10.14336/AD.2021.0302
PDF (598KB)
Pediatric Stroke: Overview and Recent Updates
Mary Hollist, Katherine Au, Larry Morgan, Padmashri A Shetty, Riddhi Rane, Abraham Hollist, Angela Amaniampong, Batool F Kirmani
2021, 12 (4): 1043-1055 | DOI: 10.14336/AD.2021.0219
PDF (388KB)
A Review of Insomnia Treatments for Patients with Mild Cognitive Impairment
Meghan K Mattos, Angela Chang, Katherine Pitcher, Carley Whitt, Lee M Ritterband, Mark S Quigg
2021, 12 (4): 1036-1042 | DOI: 10.14336/AD.2021.0423
PDF (308KB)
Role of the cGAS-STING Pathway in Aging-related Endothelial Dysfunction
Huilin Yu, Ke Liao, Yu Hu, Dingyi Lv, Minghao Luo, Qian Liu, Longxiang Huang, Suxin Luo
2022, 13 (6): 1901-1918 | DOI: 10.14336/AD.2022.0316
PDF (2568KB)
Transcranial Near Infrared Light Stimulations Improve Cognition in Patients with Dementia
Damir Nizamutdinov, Xiaoming Qi, Marvin H Berman, Gordon Dougal, Samantha Dayawansa, Erxi Wu, S. Stephen Yi, Alan B Stevens, Jason H Huang
2021, 12 (4): 954-963 | DOI: 10.14336/AD.2021.0229
PDF (459KB)
Longevity-Associated Transcription Factor ATF7 Promotes Healthspan by Suppressing Cellular Senescence and Systematic Inflammation
Yaqun Huang, Ming-Xia Ge, Yu-Hong Li, Jing-Lin Li, Qin Yu, Fu-Hui Xiao, Hong-Shun Ao, Li-Qin Yang, Ji Li, Yonghan He, Qing-Peng Kong
2023, 14 (4): 1374-1389 | DOI: 10.14336/AD.2022.1217
PDF (1647KB)
Supplement

1. Supplementary data.pdf (633KB)

Blocking C3d+/GFAP+ A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke
Qi Zhang, Chang Liu, Rubing Shi, Shiyi Zhou, Huimin Shan, Lidong Deng, Tingting Chen, Yiyan Guo, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang, Yaohui Tang
2022, 13 (3): 943-959 | DOI: 10.14336/AD.2021.1029
PDF (1915KB)
Supplement

1. Supplementary data.pdf (888KB)

New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases
Yu-Qing Ni, You-Shuo Liu
2021, 12 (8): 1948-1963 | DOI: 10.14336/AD.2021.0603
PDF (645KB)
Investigating Causality and Shared Genetic Architecture between Neurodegenerative Disorders and Inflammatory Bowel Disease
Ruijie Zeng, Jinghua Wang, Rui Jiang, Jie Yang, Chunwen Zheng, Huihuan Wu, Zewei Zhuo, Qi Yang, Jingwei Li, Felix W Leung, Weihong Sha, Hao Chen
2023, 14 (4): 1349-1359 | DOI: 10.14336/AD.2022.12209
PDF (840KB)
Systematic Review of Studies on Telomere Length in Patients with Multiple Sclerosis
Jan Bühring, Michael Hecker, Brit Fitzner, Uwe Klaus Zettl
2021, 12 (5): 1272-1286 | DOI: 10.14336/AD.2021.0106
PDF (883KB)
Supplement

1. Supplementary data.pdf (232KB)

Gut Microbiota is an Impact Factor based on the Brain-Gut Axis to Alzheimer’s Disease: A Systematic Review
Bin Zou, Jia Li, Rui-Xia Ma, Xiao-Yu Cheng, Rui-Yin Ma, Ting-Yuan Zhou, Zi-Qi Wu, Yao Yao, Juan Li
2023, 14 (3): 964-1678 | DOI: 10.14336/AD.2022.1127
PDF (1081KB)
Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-β Aggregation and Cytotoxicity
Vladimir F Lazarev, Magda Tsolaki, Elena R Mikhaylova, Konstantin A Benken, Maxim A Shevtsov, Alina D Nikotina, Mirna Lechpammer, Vladimir A Mitkevich, Alexander A Makarov, Alexey A Moskalev, Sergey A Kozin, Boris A Margulis, Irina V Guzhova, Evgeny Nudler
2021, 12 (5): 1223-1237 | DOI: 10.14336/AD.2020.1230
PDF (1913KB)
Supplement

1. Supplementary data.pdf (493KB)

Post-Stroke Neuropsychiatric Complications: Types, Pathogenesis, and Therapeutic Intervention
Jing Zhou, Yijia Fangma, Zhong Chen, Yanrong Zheng
2023, 14 (6): 2127-2152 | DOI: 10.14336/AD.2023.0310-2
PDF (939KB)