Glucocerebrosidase mRNA is Diminished in Brain of Lewy Body Diseases and Changes with Disease Progression in Blood
Perez-Roca Laia, Adame-Castillo Cristina, Campdelacreu Jaume, Ispierto Lourdes, Vilas Dolores, Rene Ramon, Alvarez Ramiro, Gascon-Bayarri Jordi, Serrano-Munoz Maria A., Ariza Aurelio, Beyer Katrin
Table 1 Clinico-neuropathological characteristics of Lewy body disease cases and controls.
DiseasenPMtime1 (range)ADstage2Br&Br3Death4 (range)M:F ratio5
pDLB689:30 (3:30-17:00)0-IIA-C74.6 (60-85)3:1
cDLB71210:30 (4:00-21:15)III-VIB-C79.0 (74-86)1.4:1
PD8127:00 (3:30-14:00)III-IV80.8 (68-93)1:1
PDD9137:10 (4:00-12:20)II-VIA-C78.7 (71-87)0.9:1
CTRL10178:40 (2:30-23:30)69.3 (55-81)1.4:1