COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile

Fulzele Sadanand, Sahay Bikash, Yusufu Ibrahim, Lee Tae Jin, Sharma Ashok, Kolhe Ravindra, Isales Carlos M

Table 2 Sequence homology between the SARS and COVID-19 isolates from different geographic locations.

AY291451.1 NC_004718.3 AY338175.1 AY348314.1 MT007544.1 EPI_ISL_429223 EPI_ISL_418001 EPI_ISL_420144 EPI_ISL_428847 EPI_ISL_427391 EPI_ISL_426565 EPI_ISL_403931 EPI_ISL_422601 MT050493.1 EPI_ISL_413214 EPI_ISL_419211 EPI_ISL_417507 EPI_ISL_406862 EPI_ISL_420799 EPI_ISL_402123 EPI_ISL_406223 EPI_ISL_407893 EPI_ISL_406597 EPI_ISL_406798 MT066176.1 MT126808.1 MT159718.1 EPI_ISL_402121 EPI_ISL_412974 EPI_ISL_403930 EPI_ISL_403962 EPI_ISL_403929 NC_045512.2 AY291451.1 100 100 100 78.8 78.8 78.7 78.7 78.8 78.7 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 NC_004718.3 100 100 100 78.8 78.8 78.7 78.7 78.8 78.7 78.8 78.8 78.7 78.8 78.8 78.8 78.7 78.8 78.8 78.8 78.8 78.8 78.7 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 78.8 AY338175.1 100 100 100 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 AY348314.1 100 100 100 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 78.7 MT007544.1 78.8 78.8 78.7 78.7 99.9 99.9 99.9 99.9 99.8 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 100 99.9 99.9 99.9 99.9 99.9 100 100 100 100 100 EPI_ISL_429223 78.8 78.8 78.7 78.7 99.9 100 100 99.9 99.9 100 99.9 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_418001 78.7 78.7 78.7 78.7 99.9 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_420144 78.7 78.7 78.7 78.7 99.9 100 100 99.9 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_428847 78.8 78.8 78.7 78.7 99.9 99.9 99.9 99.9 99.9 99.9 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_427391 78.7 78.7 78.7 78.7 99.8 99.9 100 99.9 99.9 99.9 99.9 100 99.9 99.9 99.9 99.9 100 99.9 99.9 99.9 100 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 99.9 EPI_ISL_426565 78.8 78.8 78.7 78.7 99.9 100 100 100 99.9 99.9 99.9 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_403931 78.8 78.8 78.7 78.7 99.9 99.9 100 100 100 99.9 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_422601 78.8 78.7 78.7 78.7 99.9 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 MT050493.1 78.8 78.8 78.7 78.7 99.9 99.9 100 100 100 99.9 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_413214 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_419211 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_417507 78.8 78.7 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_406862 78.8 78.8 78.7 78.7 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_420799 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_402123 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_406223 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_407893 78.8 78.8 78.7 78.7 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_406597 78.8 78.7 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_406798 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 MT066176.1 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 MT126808.1 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 MT159718.1 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_402121 78.8 78.8 78.7 78.7 99.9 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_412974 78.8 78.8 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_403930 78.8 78.8 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_403962 78.8 78.8 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 EPI_ISL_403929 78.8 78.8 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 NC_045512.2 78.8 78.8 78.7 78.7 100 100 100 100 100 99.9 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100 100