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COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile
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Fulzele Sadanand, Sahay Bikash, Yusufu Ibrahim, Lee Tae Jin, Sharma Ashok, Kolhe Ravindra, Isales Carlos M
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Table 7 List of selected human miRNAs targeting the COVID-19 genome down-regulated with age and underlying conditions. |
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miRNA | Decrease Expression in age related diseases (Human) | Reference |
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miR-15b-5p | Coronary Artery Disease | Zhu et al 2017 [37] | miR-15a-5p | Kidney disease | Shang et al 2019 [38] | miR-548c-5p | Colorectal Cancer | Peng et al 2018 [49] | miR-548d-3p | Osteosarcoma | Chen et al 2019 [50] | miR-409-3p | Osteosarcoma | Wu et al 2019 [51] | miR-30b-5p | Plasma (Aging) | Hatse et al 2014 [52] | miR-505-3p | Prostate cancer | Tang et al 2019 [53] | miR-520c-3p | Obesity/diabetes | Ortega et al 2013 [39] | miR-30e-3p | Myocardial Injury | Wang et al 2017 [40] | miR-23c | Hepatocellular carcinoma | Zhang et al 2018 [41] | miR-30d-5p | Non-small cell lung cancer | Gao et al, 2018 [42] | miR-4684-3p | Colorectal cancer | Wu et al, 2015 [43] | miR-518a-5p | Gastrointestinal tumors | Shi et al, 2016 [44] |
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