COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile
Fulzele Sadanand, Sahay Bikash, Yusufu Ibrahim, Lee Tae Jin, Sharma Ashok, Kolhe Ravindra, Isales Carlos M
Table 7 List of selected human miRNAs targeting the COVID-19 genome down-regulated with age and underlying conditions.
miRNADecrease Expression in age related diseases (Human)Reference
miR-15b-5pCoronary Artery DiseaseZhu et al 2017 [37]
miR-15a-5pKidney diseaseShang et al 2019 [38]
miR-548c-5pColorectal CancerPeng et al 2018 [49]
miR-548d-3pOsteosarcomaChen et al 2019 [50]
miR-409-3pOsteosarcomaWu et al 2019 [51]
miR-30b-5pPlasma (Aging)Hatse et al 2014 [52]
miR-505-3pProstate cancerTang et al 2019 [53]
miR-520c-3pObesity/diabetesOrtega et al 2013 [39]
miR-30e-3pMyocardial InjuryWang et al 2017 [40]
miR-23cHepatocellular carcinomaZhang et al 2018 [41]
miR-30d-5pNon-small cell lung cancerGao et al, 2018 [42]
miR-4684-3pColorectal cancerWu et al, 2015 [43]
miR-518a-5pGastrointestinal tumorsShi et al, 2016 [44]