T1-weighted MRI-driven Brain Age Estimation in Alzheimer’s Disease and Parkinson’s Disease

Beheshti Iman, Mishra Shiwangi, Sone Daichi, Khanna Pritee, Matsuda Hiroshi

Table 1 Characteristics of subjects in this study.

Training dataset Test dataset Dataset IXI OASIS ADNI PPMI ADNI PPMI Category HC HC HC HC AD PD No of Subjects 408 103 227 101 129 160 Female/Male 238/170 78/25 110/117 37/64 64/65 64/96 Age (years) 56.48±12.07 67.81±12.85 75.96±5.04 60.24±10.02 71.64±5.81 64.53±6.98 MMSE n/a n/a n/a n/a 23.25±2.26 n/a CDR n/a n/a n/a n/a 0.75±0.31 n/a GDS n/a n/a n/a n/a n/a 2.24±2.33 MoCA n/a n/a n/a n/a n/a 26.91±2.40 MDS-UPDRS Total n/a n/a n/a n/a n/a 31.97±13.13 MDS-UPDRS Part I n/a n/a n/a n/a n/a 1.35±1.57 MDS-UPDRS Part I Patient questionnaire n/a n/a n/a n/a n/a 4.05±2.79 MDS-UPDRS Part II Patient questionnaire n/a n/a n/a n/a n/a 5.71±3.96 MDS-UPDRS Part III n/a n/a n/a n/a n/a 20.85±8.72 S&E n/a n/a n/a n/a n/a 93.78±5.65 UPSIT n/a n/a n/a n/a n/a 21.01±8.19 SCOPA-AUT n/a n/a n/a n/a n/a 9.61±5.68 SBR Left Caudate n/a n/a n/a n/a n/a 1.88±0.60 SBR Right Caudate n/a n/a n/a n/a n/a 1.87±0.58 SBR Left Putamen n/a n/a n/a n/a n/a 0.77±0.31 SBR Right Putamen n/a n/a n/a n/a n/a 0.79±0.31