Immune Characteristics of Patients with Coronavirus Disease 2019 (COVID-19)

Dong Xiaotian, Wang Mengyan, Liu Shuangchun, Zhu Jiaqi, Xu Yanping, Cao Hongcui, Li Lanjuan

Table 1 Characteristics of COVID-19 patients on admission.

Characteristics COVID-19 patients (n = 18) Nucleic acid-positive <15 days (n = 12) Nucleic acid-positive≥15 days (n = 6) p value1 Age (years) 58.39 ± 17.21 56.50 ± 16.54 62.17 ± 19.47 0.527 Male, no. (%) 11 (61.11) 7 (58.33) 4 (66.67) 1.000 Hospitalization days 18.22 ± 4.86 15.75 ± 3.55 23.17 ± 2.93 <0.001* SARS-CoV-2 nucleic acid-positive duration (day) 11.89 ± 7.28 7.50 ± 3.40 20.67 ± 4.03 <0.001* Laboratory data Activated partial thromboplastin time (sec) 31.55 ± 6.04 30.68 ± 3.34 33.30 ± 9.70 0.401 International normalized ratio 0.99 ± 0.10 0.97 ± 0.06 1.05 ± 0.15 0.130 Prothrombin time (sec) 11.92 ± 1.20 11.62 ± 0.72 12.53 ± 1.76 0.130 D-dimer (μg/L) 877.56 ± 983.70 948.25 ± 1090.61 798.34 ± 325.92 0.680 White blood cell (109/L) 9.17 ± 5.24 9.29 ± 5.21 8.93 ± 5.80 0.896 Neutrophils (109/L) 8.16 ± 5.14 8.08 ± 5.21 8.30 ± 5.48 0.936 Lymphocytes (109/L) 0.66 ± 0.46 0.78 ± 0.49 0.40 ± 0.27 0.024* Hemoglobin (g/L) 131.17 ± 16.38 134.33 ± 15.95 124.83 ± 16.73 0.258 Monocytes (109/L) 0.33 ± 0.23 0.39 ± 0.25 0.22 ± 0.10 0.144 Procalcitonin (ng/mL) 0.09 ± 0.09 0.09 ± 0.09 0.10 ± 0.09 0.899 Lactate dehydrogenase (U/L) 317.78 ± 136.18 305.42 ± 76.46 342.50 ± 221.57 0.601 Total bilirubin (μmol/L) 13.16 ± 7.56 11.94 ± 7.52 15.58 ± 7.70 0.351 Alanine aminotransferase (U/L) 25.22 ± 13.52 27.00 ± 13.71 21.67 ± 13.60 0.447 Albumin (g/L) 37.61 ± 5.00 38.55 ± 5.66 35.72 ± 2.82 0.269 Glutamyl transpeptidase (U/L) 45.78 ± 32.43 43.58 ± 24.99 50.17 ± 46.55 0.697 Alkaline phosphatase (U/L) 76.00 ± 31.60 81.42 ± 34.48 65.17 ± 23.86 0.318 Creatinine (μmol/L) 86.83 ± 67.25 94.08 ± 81.24 72.33 ± 21.91 0.534 Aspartate aminotransferase (U/L) 26.56 ± 14.02 26.17 ± 10.05 27.33 ± 21.09 0.874 C reactive protein (mg/L) 36.70 ± 44.02 28.68 ± 38.61 52.74 ± 53.33 0.288 Blood lactic acid (mmol/L) 2.13 ± 0.94 2.14 ± 1.16 2.10 ± 0.30 0.933 Partial pressure of oxygen (mmHg) 96.55 ± 47.30 108.66 ± 50.37 72.33 ± 31.14 0.128 Oxygen saturation (%) 94.35 ± 7.07 96.51 ± 2.73 90.03 ± 10.95 0.210 Hematocrit (%) 41.76 ± 7.57 42.02 ± 6.90 41.25 ± 9.48 0.847 Potassium (mmol/L) 3.65 ± 0.44 3.79 ± 0.33 3.36 ± 0.52 0.043* Sodium (mmol/L) 138.11 ± 10.44 139.75 ± 3.79 134.83 ± 17.87 0.533 Creatine kinase (U/L) 22.33 ± 7.68 22.25 ± 8.57 22.50 ± 6.22 0.950