Immune Characteristics of Patients with Coronavirus Disease 2019 (COVID-19)

Dong Xiaotian, Wang Mengyan, Liu Shuangchun, Zhu Jiaqi, Xu Yanping, Cao Hongcui, Li Lanjuan

Table 3 Lymphocyte subsets in COVID-19 patients at diagnosis and at discharge.

Lymphocyte subsets Normal range COVID-19 patients (n = 15) Nucleic acid-positive < 15 days (n = 9) Nucleic acid-positive ≥ 15 days (n = 6) p value† At diagnosis At discharge1 At diagnosis At discharge2 At diagnosis At discharge3 Lymphocytes (/μL) 1530-3700 828.67 ± 700.99 1301.53 ± 566.77* 1100.56 ± 784.76 1372.89 ± 558.81 420.83 ± 240.61 1194.50 ± 613.92* 0.035* T cells (/μL) 955-2860 517.07 ± 496.82 906.87 ± 412.71* 706.78 ± 567.01 949.44 ± 424.35 232.50 ± 121.53 843.00 ± 425.02* 0.038* CD3+CD4+CD8- T cells (/μL) 550-1440 292.13 ± 323.05 524.07 ± 294.16* 410.44 ± 375.48 548.67 ± 332.58 114.67 ± 60.32 487.17 ± 250.17* 0.047* CD3+CD4-CD8+ T cells (/μL) 320-1250 192.40 ± 170.89 324.53 ± 186.26* 257.44 ± 191.84 339.33 ± 147.95 94.83 ± 62.08 302.33 ± 247.24 0.039* CD4+/CD8+ ratio 0.71-2.78 1.69 ± 1.11 2.05 ± 1.18 1.81 ± 1.27 1.86 ± 1.13 1.51 ± 0.90 2.32 ± 1.30 0.629 B cells (/μL) 90-560 168.40 ± 135.75 221.73 ± 111.09* 219.44 ± 148.39 226.44 ± 131.06 91.83 ± 68.10 214.67 ± 83.52* 0.072 NK cells (/μL) 150-1100 120.13 ± 82.92 140.93 ± 123.40 148.56 ± 91.59 179.78 ± 118.71 77.50 ± 46.82 82.67 ± 115.31 0.106