Trends in LDL-C and Non-HDL-C Levels with Age

Zhang Peng, Su Qian, Ye Xiaomiao, Guan Ping, Chen Chengjun, Hang Yanwen, Dong Jian, Xu Zhongjie, Hu Wei

Table 3 Associations with non-HDL-C level evaluated by univariate linear regression analyses.

Female Male Variable Coef. 95% CI P Variable Coef. 95% CI P Pooled Age 0.026 0.026~0.027 <0.001 Age 0.005 0.004~0.005 <0.001 Systolic BP / / / Systolic BP / / / Diastolic BP 0.021 0.017~0.033 0.003 Diastolic BP 0.005 0.003~0.017 0.005 Glucose (mmol/L) 0.015 0.011~0.021 0.004 Glucose (mmol/L) 0.211 0.139~0.341 0.004 BMI (kg/m2) 0.054 0.039~0.061 <0.001 BMI (kg/m2) 0.079 0.067~0.087 <0.001 Inactive lifestyle 0.031 0.022~0.041 0.003 Inactive lifestyle 0.054 0.034~0.069 0.003 Moderate drinking / / / Moderate drinking 0.049 0.041~0.051 <0.001 Smoking / / / Smoking 0.068 0.056~0.099 0.008 Age-stratified Age phase I: 18 ≤ age ≤ 56 (N = 61,420) Age phase I: 18 ≤ age ≤ 33 (N = 22,942) Age 0.033 0.033~0.034 <0.001 Age 0.052 0.049~0.055 <0.001 Systolic BP / / / Systolic BP 0.005 0.002~0.023 0.027 Diastolic BP 0.029 0.021~0.031 <0.001 Diastolic BP / / / Glucose (mmol/L) 0.201 0.178~0.231 <0.001 Glucose (mmol/L) 0.312 0.201~0.402 0.004 BMI (kg/m2) 0.058 0.048~0.068 <0.001 BMI (kg/m2) 0.079 0.056~0.087 <0.001 Inactive lifestyle 0.028 0.021~0.039 <0.001 Inactive lifestyle 0.036 0.026~0.057 0.004 Moderate drinking / / / Moderate drinking 0.034 0.023~0.045 <0.001 Smoking / / / Smoking 0.079 0.065~0.101 0.008 Age phase II: 34 ≤ age ≤ 56 (N = 59,807) Age 0.005 0.004~0.006 <0.001 Systolic BP / / / Diastolic BP 0.007 0.005~0.011 0.006 Glucose (mmol/L) 0.192 0.136~0.203 <0.001 BMI (kg/m2) 0.061 0.053~0.072 <0.001 Inactive lifestyle 0.101 0.079~0.209 0.002 Moderate drinking 0.063 0.045~0.076 0.008 Smoking 0.114 0.094~0.203 0.009 Age phase II: age ≥ 57 (N = 8,748) Age phase III: age ≥ 57 (N = 15,653) Age -0.014 -0.017~-0.011 <0.001 Age -0.017 -0.019~-0.015 <0.001 Systolic BP / / / Systolic BP / / / Diastolic BP 0.009 0.005~0.013 0.004 Diastolic BP 0.006 0.003~0.023 0.034 Glucose (mmol/L) 0.065 0.054~0.105 0.003 Glucose (mmol/L) 0.114 0.098~0.231 0.006 BMI (kg/m2) 0.041 0.038~0.059 <0.001 BMI (kg/m2) 0.042 0.037~0.053 <0.001 Inactive lifestyle 0.031 0.022~0.044 <0.001 Inactive lifestyle 0.041 0.029~0.057 0.005 Moderate drinking / / / Moderate drinking 0.041 0.036~0.055 0.003 Smoking / / / Smoking 0.031 0.019~0.065 0.007