Trends in LDL-C and Non-HDL-C Levels with Age

Zhang Peng, Su Qian, Ye Xiaomiao, Guan Ping, Chen Chengjun, Hang Yanwen, Dong Jian, Xu Zhongjie, Hu Wei

Table 4 Age associations with the LDL-C levels in each age phase adjusted for confounding factors.

Female Male Independent variable Coef. 95% CI P Independent variable Coef. 95% CI P Age phase I: 18 ≤ age ≤ 56 Age phase I: 18 ≤ age ≤ 33 Age 0.018 0.018~0.019 <0.001 Age 0.025 0.021~0.030 <0.001 Systolic BP / / / Systolic BP / / / Diastolic BP 0.004 0.002~0.007 <0.001 Diastolic BP / / / Glucose (mmol/L) 0.115 0.105~0.125 <0.001 Glucose (mmol/L) 0.169 0.153~0.186 <0.001 BMI (kg/m2) 0.041 0.032~0.050 <0.001 BMI (kg/m2) 0.071 0.055~0.087 <0.001 Inactive lifestyle 0.043 0.032~0.089 <0.001 Inactive lifestyle 0.021 0.011~0.067 <0.001 Moderate drinking / / / Moderate drinking 0.031 0.012~0.071 <0.001 Smoking / / / Smoking 0.075 0.061~0.079 0.002 Age phase II: 34 ≤ age ≤ 56 Age / / / Systolic BP / / / Diastolic BP 0.007 0.003~0.010 <0.001 Glucose (mmol/L) 0.030 0.022~0.037 <0.001 BMI (kg/m2) 0.035 0.023~0.048 <0.001 Inactive lifestyle 0.023 0.013~0.037 0.004 Moderate drinking 0.061 0.054~0.201 0.003 Smoking 0.103 0.108~0.232 0.001 Age phase II: age ≥ 57 Age phase III: age ≥ 57 Age -0.013 -0.016~-0.011 0.001 Age -0.008 -0.010~-0.005 <0.001 Systolic BP / / / Systolic BP / / / Diastolic BP 0.012 0.007~0.018 <0.001 Diastolic BP 0.004 0.001~0.007 0.002 Glucose (mmol/L) 0.051 0.019~0.083) <0.001 Glucose (mmol/L) 0.038 0.026~0.050 <0.001 BMI (kg/m2) 0.024 0.010~0.038 0.002 BMI (kg/m2) 0.025 0.010~0.040 <0.001 Inactive lifestyle 0.021 0.016~0.037 0.007 Inactive lifestyle 0.034 0.020~0.043 0.004 Moderate drinking / / / Moderate drinking 0.043 0.032~0.077 0.009 Smoking / / / Smoking 0.023 0.016~0.052 0.008