Infrapatellar Fat Pad and Knee Osteoarthritis
Zeng Ni, Yan Zhi-Peng, Chen Xin-Yuan, Ni Guo-Xin
Table 1 The relationship between MRI features of IFP and knee characteristics.
Ref. (year)SubjectsFindings
33 (2018)KOA patientsIncreased signal intensity in the IFP was associated with knee structural abnormalities in tibiofemoral compartment.
34 (2018)KOA patientsIFP signal intensity is associated with the occurrence of knee replacement.
28 (2017)KOA patients1.The increase in 3D MRI heterogeneity was greater in progressor and OA knees than non-progressor knees and healthy knees, respectively. 2. Increase in 3D IFP MRI signal and signal heterogeneity may be associated with radiographic/symptomatic progression of OA, when compared to non-progressive OA or healthy knees
35 (2016)Older adultsThe IFP signal abnormalities has a potentially important role in OA progression.
81 (2015)Adults without KOA1.IFP at baseline was associated with reduced knee pain at follow-up and lateral tibial cartilage volume loss; 2. IFP size is not simply a marker of systemic obesity.
82 (2015)PFJ OA patients1. IFP volume was greater in the PFJ OA group than controls and it was directly related to PFJ OA pain; 2. Larger IFP was associated with worse pain.
2 (2015)Older adults1.IFP maximal area in women was significantly associated with changes in knee pain and reduced loss of medial and lateral tibial cartilage volume; 2. IFP plays a protective role in joint degeneration in the elderly.
36 (2014)Older adults1.IFP maximum area was significantly associated with joint space narrowing and medial osteophytes, knee tibial and patellar cartilage volume, tibial cartilage defects, any BMLs, and knee pain on a flat surface; 2.IFP maximum area is beneficially associated with radiographic OA, MRI structural pathology and knee pain on a flat surface suggesting a protective role for IFP possibly through shock absorption.
15 (2014)KOA patients1.The severity of inflammation in the IFP were associated with the severity of pain in KOA; 2.DCE-MRI is a promising method to study the impact of inflammation in KOA
30 (2010)KOA patientsSubjects who are prone to growth or enlargement of the IFP may also be more prone to symptomatic OA.