Serum Occludin as a Biomarker to Predict the Severity of Acute Ischemic Stroke, Hemorrhagic Transformation, and Patient Prognosis
Li Weili, Qi Zhifeng, Kang Huining, Qin Xuzhen, Song Haiqing, Sui Xueqin, Ren Yi, Ji Xunming, Ma Qingfeng, Jian Liu Ke
Table 4 Analysis of prognostic risk factors for CI with non-reperfusion therapy.
VariablemRS=0-2
(n=59)
mRS≥3
(n=26)
P values
Age — yr66.46±13.3468.32±14.760.570
Male sex — no. (%)43 (72.9)17 (65.4)0.284
Atrial fibrillation — no. (%)4 (6.8)7 (26.9)0.028
Diabetes mellitus — no. (%)13 (22.0)4 (15.4)0.680
Hypertension — no. (%)25 (42.4)15 (57.7)0.192
Median NIHSS score (IQR)2 (1-4)12 (10-14)0.000
Previous stroke — no. (%)10 (9.3)7 (12.7)0.493
Median Onset to Door time— hr. (IQR)5 (2.5-12)5.75 (4.5-9.75)0.509
Serum occludin levels (ng/mL)3.93±1.165.11±1.48<0.001
LDL-C (mmol/L)2.77±1.023.06±0.970.266
HDL-C (mmol/L)1.27±0.371.23±0.350.683
TG (mmol/L)1.79±1.101.77±0.860.938
GLU (mmol/L)7.58±3.747.61±3.180.969
FIB (g/L)3.61±0.804.30±1.270.007
WBC (109/L)7.28±2.189.01±1.960.002
NEUT (%)63.43±11.4274.51±13.980.001