Sirtuins and their Biological Relevance in Aging and Age-Related Diseases

Zhao Lijun, Cao Jianzhong, Hu Kexin, He Xiaodong, Yun Dou, Tong Tanjun, Han Limin

Table 4 Some age-related diseases in elderly population.

Aging and age-related disease Neurodegenerative diseases Presbyophrenia, Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, Amyotrophic lateral sclerosis Cardiovascular and cerebrovascular diseases Hypertension, Coronary disease, Cardiomyopathies, Elder valvular heart disease, Arrhythmia, Cardiac failure, Cerebral infraction, Atherosclerosis Metabolic related diseases Diabetes, Metabolic syndrome, Osteoporosis, Hyperinsulinism-induced dyslipidaemia, Uarthritis, Non-alcoholic hepatic steatosis, Others Scapulohumeral periarthritis, Chronic bronc, Chronic inflammation, Cancer