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Aging and Disease    2016, Vol. 7 Issue (3) : 246-253     DOI: 10.14336/AD.2015.0925
Original Article |
Predictors of Difficulty in Medication Intake in Europe: a Cross-country Analysis Based on SHARE
Daniela Figueiredo1,2,Laetitia Teixeira3,Veronica Poveda3,Constança Paúl3,4,Alice Santos-Silva5,Elísio Costa5
1University of Aveiro, School of Health Sciences, Aveiro, Portugal.
2Center for Health Technology and Services Research (CINTESIS.UA), Aveiro, Portugal.
3Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal.
4CINTESIS, Center for Health Technology and Services Research (CINTESIS), Porto, Portugal.
5UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal.
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Abstract  

The aim of this study is to evaluate the prevalence and the predictors of difficulty in medication intake across Europe, using a cross-sectional design. We used data from all participants in the wave 4 of the SHARE (Survey of Health, Ageing, and Retirement in Europe) database, which is a cross national European survey. The difficulty in take medication was evaluated using an item from the “Limitations with activities of daily living”. Clinical and sociodemographic variables were evaluated as potential predictors. A total of 58 124 individual have been included in this work (mean age=64.9 ± 10.4 years; 43.3% male). The rate of difficulty in taking medication across the 16 European evaluated countries was 2.1%, presenting Spain the highest rate (5.7%) and Switzerland the lowest (0.6%). Increasing age, physical inactivity, physical limitations (mobility, arms function and fine motor limitations, and difficulties in picking up a small coin from a table), a poor sense of meaning in life, and losses in memory and concentration are independent and significant variables associated with difficulty in medication intake across Europe. Predictors of difficulties in medication intake are multicausal, including factors related to physical, cognitive and psychological conditions. Interventions aiming to optimize adherence to medication, particularly in elderly population, need to consider this diversity of determinants.

Keywords difficulty in take medication      elderly      SHARE      non-adherence      persistence     
Corresponding Authors: Elísio Costa   
Issue Date: 09 January 2016
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Daniela Figueiredo
Laetitia Teixeira
Veronica Poveda
Constança Paúl
Alice Santos-Silva
Elísio Costa
Cite this article:   
Daniela Figueiredo,Laetitia Teixeira,Veronica Poveda, et al. Predictors of Difficulty in Medication Intake in Europe: a Cross-country Analysis Based on SHARE[J]. A&D, 2016, 7(3): 246-253.
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http://www.aginganddisease.org/EN/10.14336/AD.2015.0925     OR     http://www.aginganddisease.org/EN/Y2016/V7/I3/246
[1] Centers for Disease Control and Prevention (2003). Public Health and Aging: Trends in aging - United States and Worldwide. MMWR Weekly, 52:101-106.
[2] Roebuck M, Liberman J, Gemmill-Toyama M, Brennan T (2011). Medication adherence leads to lower health care use and costs despite increased drug spending. Health Aff, 30: 91-99.
[3] Bosworth H, Granger B, Mendys P, Brindis R, Burkholder R, Czajkowski S, Daniel J, Ekman I, Ho M, Johnson M, Kimmel S, Liu L, Musaus J, Shrank W, Buono E, Weiss K, Granger C (2011). Medication Adherence: A Call for Action. Am Heart J, 162:412-424.
[4] Sabaté E (2003). Adherence to long-term therapies: Evidence for action. WHO Library Cataloguing-in-Publication Data, Geneve.
[5] Nieuwlarr R, Wilczynski N, Navarro T, Hobson N, Jeffery R, Keepanasseril A, Agoritsas T, Mistry N, Iorio A, Jack S, Sivaramalingam B, Iserman E, Mustafa R, Jedraszewski D, Cotoi C, R Haynes (2014). Interventions for enhancing medication adherence (Review). Cochrane Database Syst Rev, 11:CD000011.
[6] Dulmen S, Sluijs E, Dijk L, Ridder D, Heerdink R, Bensing J (2007). Patient adherence to medical treatment: A review of reviews. BMC Health Serv Res, 7:55.
[7] Krueger K, Berger B, Felkey B (2005). Medication adherence and persistence: A comprehensive review. Adv Ther, 22:313-356.
[8] Brown M, Brussell J (2011). Medication Adherence: WHO Cares?. Mayo Clin Proc, 86:304-314.
[9] George J, Elliott R, Stewart D (2008). A sytematic review of interventions to improve medication taking in elderly patients prescribed multiple medications. Drugs Aging, 25: 307-324.
[10] Insel K, Morrow D, Brewer B, Figueiredo A (2006). Executive function, working memory, and medication adherence among older adults. J Gerontol B Psychol Sci Soc Sci, 61B: 102-107.
[11] Corsonello A, Pedone C, Lattanzio F, Lucchetti M, Garasto S, Carbone C, Greco C, Fabbietti P, Incalzi R (2009). Regimen complexity and medication nonadherence in elderly patients. Therapeutics and Clinical Risk Management, 5. 209-216.
[12] Alosco M, Spitznagel M, Dulmen M, Raz N, Cohen R, Sweet L, Colbert L, Josephson R, Hughes J, Rosneck J, Gunstad J (2012). Cognitive function and treatment adherence in older adults with heart failure. Psychosom Med, 79: 965-973.
[13] Goldney R, Fisher L (2005). Use of prescribed medications in a South Australian community sample. Med J Aust, 183:251-253.
[14] Elliott R (2006). Problems with medication use in the elderly: An Australian Perspective. Journal of Pharmacy Practice and Research, 36: 58-66.
[15] Hubbard R, O’Mahony M, Woodhouse K (2013). Medication prescribing in frail older people. Eur J Clin Pharmacol, 69: 319-326.
[16] Börsch-Supan A, Brandt M, Hunkler C, Kneip T, Korbmacher J, Malter F, Schaan B, Stuck S, Zuber S, SHARE Central Coordination Team (2013). Data Resource Profile: the Survey of Health, Ageing and Retirement in Europe (SHARE). Int J Epidemiol, 42: 992-1001.
[17] Malter F, Börsch-Supan A(Eds.) (2013). SHARE Wave 4: Innovations & Methodology, Munich: MEA, Max Planck Institute for Social Law and Social Policy.
[18] Jin J, Sklar GE, Min Sen V, Chuen Li S (2008). Factors affecting therapeutic compliance: A review from the patient’s perspective. Ther Clin Risk Manag, 4:269-286.
[19] Barkhof E, Meijer CJ, de Sonneville LM, Linszen DH, de Haan L (2012). Interventions to improve adherence to antipsychotic medication in patients with schizophrenia--a review of the past decade. Eur Psychiatry, 27: 9-18.
[20] Martin LR, Williams SL, Haskard KB, DiMatteo MR (2005). The challenge of patient adherence. Ther Clin Risk Manag, 3:189-199.
[21] Gray S, Mahoney J, Blough D (2001). Medication adherence in elderly patients receiving home health services following hospital discharge. Ann Pharmacother, 35:539-545.
[22] Vik S, Hogan D, Patten S, Johnson J, Romonko-Slack L, Maxwell C (2006). Medication nonadherence and subsequent risk of hospitalisation and mortality among older adults. Drugs Aging, 4: 345-356.
[23] Ruscin J, Semla T (1996). Assessment of medication management skills in older outpatients. Ann Pharmacother, 30:1083-1088.
[24] Krause N (2004). Stressors in highly valued roles, meaning in life, and the physical health status of older adults. J Gerontol B Psychol Sci Soc Sci, 59: S287-S297.
[25] Krause N (2009). Meaning in Life and Mortality. J Gerontol B Psychol Sci Soc Sci, 62: 517-527.
[26] Park C (2007). Religiousness/Spirituality and Health: A meaning systems perspective. J Behav Med: 319-328.
[27] De Jongh T, Gurol-Urganci I, Vodopivec-Jamsek V, Car J, Atun R (2012). Mobile phone messaging for facilitation self-managment of long-term illness (Review). Cochrane Database Syst Rev, 12: CD007459.
[28] Mira J, Navarro I, Botella F, Borrás F, Nuño-Solinis R, Orozco D, Iglesias-Alonso F, Pérez-Pérez P, Lorenzo S, Toro N (2014). A Spanish Pillbox App for Elderly Patients Taking Multiple Medications: Randomized Controlled Trial. J Med Internet Res, 16: e99.
[29] Purdie M, Dunne M, Boyle F, Cook M, Najman J (2002). Health and demographic characteristics of respondents in an Australian national sexuality survey: Comparasion with population norms. J Epidemiol Community Health: 748-753.
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