Perspective
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Chronic Cerebral Deterioration - A Comprehensive View of Old-Age Cerebral Deterioration
Jan Willem van Dalen
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Addressing Healthy Aging: Time to Stop a Tsunami of Rising Alzheimer’s Disease
Nobel Chenggong Zong, Yuhan Zhang, Yuanli Huang, Hua Cai
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Spatiotemperal Dynamics of Osteoarthritis: Bridging Insights from Bench to Bedside
Xiwei Fan, Hong Xu, Indira Prasadam, Antonia Rujia Sun, Xiaoxin Wu, Ross Crawford, Yanping Wang, Xinzhan Mao
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Revisiting the Benefits of Exercise for Alzheimer's Disease through the Lens of Ferroptosis: A New Perspective
Zikang Hao, Xinmeng Guo, Jiawen Wu, Guang Yang
Review
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Applications of Chitosan and its Derivatives in the Treatment of Osteoarthritis
Xuexuan Fan, Guangze Chen, Sishu Wang, Xinhong Liu, Sai Huang, Cong Feng, Xiaolei Jiang
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Mitochondrial Quality Control: A New Perspective in Skeletal Muscle Dysfunction of Chronic Obstructive Pulmonary Disease
Yanxia Song, Xiaoyu Han, Yingqi Wang, Kangxia Li, Huanping Li, Yizhu Tian, Xiaoqing Ma, Weibing Wu, Jihong Wang
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Metabolic Dysfunction in Idiopathic Intracranial Hypertension: Current Theories and Updates
Hui Li, Lu Liu, Yifan Zhou, Huimin Jiang, Weiyue Zhang, Chenxia Zhou, Chuanjie Wu, Chen Zhou, Xunming Ji
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Role of AMPK and Sirtuins in Aging Heart: Basic and Translational Aspects
Maria Luisa Barcena, Muhammad Aslam, Kristina Norman, Christiane Ott, Yury Ladilov
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Immunometabolism In Brain Aging and Neurodegeneration: Bridging Metabolic Pathways and Immune Responses
Shokofeh Rahimpour, Briana L. Clary, Sanaz Nasoohi, Yohanna S. Berhanu, Candice M. Brown
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Multi-Omics Research on Angina Pectoris: A Novel Perspective
Haiyang Chen, Lijun Zhang, Meiyan Liu, Yanwei Li, Yunpeng Chi
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Bone Health and Physical Activity - The Complex Mechanism
Alicja Nowak, Małgorzata Ogurkowska
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Gut Microbiota-Immune System Interactions in Health and Neurodegenerative Diseases: Insights into Molecular Mechanisms and Therapeutic Applications
Rengasamy Balakrishnan, Shin-Il Kang, Ji-Yeon Lee, Yang-Kook Rho, Byoung-Kook Kim, Dong-Kug Choi
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Senescent Macrophages and the Lung Cancer Microenvironment: A New Perspective on Tumor Immune Evasion
Lexin Qin, Tingting Liang, Xinyu Zhu, Wentao Hu, Bo Li, Meidan Wei, Jiaxin Zhang, Jianxiang Li, Jin Wang
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Mechanistic Insights and Emerging Therapeutic Targets of Alzheimer's Disease: From the Perspective of Inter-Organ Crosstalk
Jianqiong Yin, Wei Peng, Lu Lu, Zhen Hong, Dong Zhou, Jinmei Li
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Pros and Cons of Human Brain Organoids to Study Alzheimer’s Disease
Andrea Sainz, Fernando Pérez-Cerdá, Alberto Pérez-Samartín, Mitradas Panicker, Asier Ruiz, Carlos Matute
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Alpha-Glucosidase Inhibitors in Aging and Aging-Related Diseases: Clinical Applications and Relevant Mechanisms
Ling Zhong, Jielin Yang, Jibran Nehal Syed, Yuwei Zhang, Yan Tian, Xianghui Fu
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Epigenetic Clocks: Beyond Biological Age, Using the Past to Predict the Present and Future
Runyu Liang, Qiang Tang, Jia Chen, Luwen Zhu
Original Article
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Upregulation of Na/H Exchanger in Astrogliosis and Early Alzheimer’s Disease Pathogenesis
Jenelle M. Collier, Shamseldin Metwally, Mary McFarland, Sanjana Krishna, Pallavi Kurella, Victoria Fiesler, Mark Stauffer, Gulnaz Begum, Julia Kofler, Dandan Sun
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Aerobic Exercise Improves Cognitive Recovery in Mice with Chronic Cerebral Hypoperfusion by Modulating the Annexin-A1-MAPK Axis and Astrocyte Polarization
Wei Zhang, Jing He, Yuxin Wang, Xiaozhen Wang, He Jin, Xu Zhang, Ling Kong, Yanchuan Wu, Yong Yang, Rong Wang
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Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis
Anna Tylutka, Piotr Żabiński, Łukasz Walas, Agnieszka Zembron-Lacny
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TBC1D15 Inhibits Autophagy of Microglia through Maintaining the Damaged Swelling Lysosome in Alzheimer’s Disease
You Wu, Yong-ming Zhou, Wei Wu, Wan-rong Jiang, Xin-yuan Zhang, Si-yuan Song, Zhao-hui Yao
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A longitudinal Analysis of the Association between Socioeconomic Position and Multimorbidity in the European Prospective Investigation into Cancer and Nutrition Study
Luca Manfredi, Barbara Sodano, Chiara Raganato, Federica Buscema, Lorenzo Milani, Alberto Catalano, Heinz Freisling, Pietro Ferrari, Alem Abraha, Rudolf Kaaks, Verena Katzke, Salvatore Panico, Christian Skødt Antoniussen, Christina C. Dahm, Sandar Tin Tin, Roel Vermeulen, Ilonca Vaartjes, Anne Tjønneland, Anja Olsen, Sandra Colorado-Yohar, Sara Grioni, Marc J. Gunter, Matthias B. Schulze, Reynalda Cordova, Maria-Jose Sánchez, Catalina Bonet Bonet, Rosario Tumino, Olatz Mokoroa, Giovanna Masala, Marcela Guevara Eslava, Monique Verschuren, Carlotta Sacerdote, Fulvio Ricceri
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Targeting Mitochondrial Integrity as a New Senolytic Strategy
Eliska Vacurova, Edita Vlachova, Jan Stursa, Klara Bohacova, Tereza Havrlantova, Vojtech Skop, Barbora Judita Kasperova, Lukas Werner, Jiri Neuzil, Martin Haluzik, Sona Stemberkova Hubackova
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Fecal Microbiota Transplantation from Young-Trained Donors Improves Cognitive Function in Old Mice Through Modulation of the Gut-Brain Axis
Camila Cerna, Nicole Vidal-Herrera, Francisco Silva-Olivares, Daniela Álvarez, Camila González-Arancibia, Miltha Hidalgo, Pabla Aguirre, José González-Urra, Camila Astudillo-Guerrero, Michel Jara, Omar Porras, Gonzalo Cruz, Christian Hodar, Paola Llanos, Pamela Urrutia, Claudia Ibacache-Quiroga, Yulia Nevzorova, Francisco Javier Cubero, Marco Fuenzalida, Samanta Thomas-Valdés, Gonzalo Jorquera
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Lifelong Glutathione Deficiency in Mice Increased Lifespan and Delayed Age-Related Motor Declines
J. Thomas Mock, Paapa Mensah-Kane, Delaney L. Davis, Jessica M. Wong, Philip H. Vann, Michael J. Forster, Nathalie Sumien
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Exposure of Young Mice to Atmospherically Relevant PM2.5 Has Sex-Dependent Long-Lasting Impacts on the Skeletal Muscle System
Wenduo Liu, Zilin Wang, Min-Hye Kim, Yu Gu, Hyun-Jaung Sim, Jeong-Chae Lee, Sung-Ho Kook, Sang Hyun Kim
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Oxidative Stress Promotes Axonal Atrophy through Alterations in Microtubules and EB1 Function
Samuel Shields, Emilia Gregory, Oliver Wilkes, IIlana Gozes, Natalia Sanchez-Soriano