Editorial
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Genetic Risk, Inflammation, and Therapeutics: An Editorial Overview of Recent Advances in Aging Brains and Neurodegeneration
Vivek Gupta, Nitin Chitranshi, Veer Bala Gupta
Commentary
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From Insight to Eyesight: Unveiling the Secrets of the Insulin-Like Growth Factor Axis in Retinal Health
Raju V. S. Rajala, Ammaji Rajala
Opinion
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Ocular delivery of Pigment Epithelium-Derived Factor (PEDF) as a neuroprotectant for Geographic Atrophy
Emily F. Warner, Laura Vaux, Kara Boyd, Peter S. Widdowson, Katie M. Binley, Andrew Osborne
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Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders
Ashish Kumar, Fred Kim, Dong-Keun Song, Jai Jun Choung
Perspective
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Current Advances and Future Perspectives on Mesenchymal Stem Cell-Derived Extracellular Vesicles in Alzheimer's Disease
Wenjing Zhang, Russell Uyemura, Kun Zhong, Rui Guo, Li Zhong
Review
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Coupling of Alzheimer’s Disease Genetic Risk Factors with Viral Susceptibility and Inflammation
Can Cao, Gaoshuang Fu, Ruodan Xu, Ning Li
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Molecular Mechanisms of Glaucoma Pathogenesis with Implications to Caveolin Adaptor Protein and Caveolin-Shp2 Axis
Mojdeh Abbasi, Vivek Gupta, Nitin Chitranshi, Petros Moustardas, Reza Ranjbaran, Stuart L. Graham
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Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve
Akanksha Salkar, Roshana Vander Wall, Devaraj Basavarajappa, Nitin Chitranshi, Gabriella E. Parilla, Mehdi Mirzaei, Peng Yan, Stuart Graham, Yuyi You
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Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43
Jianxing Song
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Genomic Insights into Dementia: Precision Medicine and the Impact of Gene-Environment Interaction
Anjali Tripathi, Vinay Kumar Pandey, Garima Sharma, Ashish Ranjan Sharma, Anam Taufeeq, Abhimanyu Kumar Jha, Jin-Chul Kim
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Physical Exercise Counteracts Aging-Associated White Matter Demyelination Causing Cognitive Decline
Tanya H. Butt, Makoto Tobiume, Diane B. Re, Shingo Kariya
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Mechanisms of Transsynaptic Degeneration in the Aging Brain
Roshana Vander Wall, Devaraj Basavarajappa, Alexander Klistoner, Stuart Graham, Yuyi You
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Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis
Lushuang Xie, Qiaofeng Wu, Kelin Li, Mohammed A. S. Khan, Andrew Zhang, Bharati Sinha, Sihui Li, Sulie L. Chang, David L. Brody, Mark W. Grinstaff, Shuanhu Zhou, Gil Alterovitz, Pinghua Liu, Xin Wang
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Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection?
Santra Brenna, Markus Glatzel, Tim Magnus, Berta Puig, Giovanna Galliciotti
Original Article
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Brain Insulin Signaling is Associated with Late-Life Cognitive Decline
Han Tong, Ana W. Capuano, Owen T. Carmichael, Kathryn L. Gwizdala, David A. Bennett, Rexford S. Ahima, Steven E. Arnold, Zoe Arvanitakis
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Aging and Sex Differences in Brain Volume and Cerebral Blood Flow
Hiroto Kawano, Shigeki Yamada, Yoshiyuki Watanabe, Satoshi Ii, Tomohiro Otani, Hirotaka Ito, Ko Okada, Chifumi Iseki, Motoki Tanikawa, Shigeo Wada, Marie Oshima, Mitsuhito Mase, Kazumichi Yoshida
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Association of Plasma Markers of Alzheimer’s Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging
Mustapha Bouhrara, Keenan A. Walker, Joseph S. R. Alisch, Zhaoyuan Gong, Caio H. Mazucanti, Alexandria Lewis, Abhay R. Moghekar, Lisa Turek, Victoria Collingham, Nader Shehadeh, Giovanna Fantoni, Mary Kaileh, Christopher M. Bergeron, Jan Bergeron, Susan M. Resnick, Josephine M. Egan
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Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension
María del Cielo Sánchez-Migallón, Johnny Di Pierdomenico, Alejandro Gallego-Ortega, Diego García-Ayuso, Manuel Vidal-Sanz, Marta Agudo-Barriuso, Francisco J. Valiente-Soriano
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Type-2 Diabetes Alters Hippocampal Neural Oscillations and Disrupts Synchrony between the Hippocampus and Cortex
Gratianne Rabiller, Zachary Ip, Shahram Zarrabian, Hongxia Zhang, Yoshimichi Sato, Azadeh Yazdan-Shahmorad, Jialing Liu
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Age-Related Changes in the Glycolytic Enzymes of M2-Isoform of Pyruvate Kinase and Fructose-1,6-Bisphosphate Aldolase: Implications to Age-Related Macular Degeneration
Ammaji Rajala, Raju V. S. Rajala
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Ovariectomy and High Fat-Sugar-Salt Diet Induced Alzheimer's Disease/Vascular Dementia Features in Mice
Sahar Sweetat, Moti Ben Shabat, Paschalis Theotokis, Nir Suissa, Eleni Karafoulidou, Olga Touloumi, Rami Abu-Fanne, Oded Abramsky, Gilly Wolf, Ann Saada, Amit Lotan, Nikolaos Grigoriadis, Hanna Rosenmann
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Glaucoma, More than Meets the Eye: Patterns of Demyelination Revealed in Human Postmortem Glaucomatous Optic Nerve
Gabriella E. Parrilla, Akanksha Salkar, Roshana Vander Wall, Vivek Gupta, Stuart L. Graham, Yuyi You
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Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects
Ting Shen, Samran Sheriff, Yuyi You, Jiyang Jiang, Angela Schulz, Heather Francis, Mehdi Mirzaei, Danit Saks, Viswanthram Palanivel, Devaraj Basavarajappa, Nitin Chitranshi, Veer Gupta, Wei Wen, Perminder S. Sachdev, Huixun Jia, Xiaodong Sun, Stuart L. Graham, Vivek K. Gupta
