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2023
Impact Factor
7.0

Early Edition

The papers published below have been examined by the peer-review process and accepted for publication in Aging and Disease. A “Just Accepted” paper is published online shortly after its acceptance, which allows authors to make their results available to the research community as soon as possible after acceptance. When the final version appears, the version of early edition is replaced with the final version, and the paper is moved to the appropriate issue on the Aging and Disease website. The paper will no longer appear in the “Just Accepted”. However, all links (the URL) will not change. “Just Accepted” papers are citable from that date they are posted. To cite this manuscript please include its Digital Object Identifier (DOI), which is identical for all formats of publication.
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Total 159 results are found
Cellular Components of the Blood-Brain Barrier and Their Involvement in Aging-Associated Cognitive Impairment
Kaiyuan Shen, Yi Shi, Xin Wang, Susan WS Leung
| DOI: 10.14336/AD.202.0424
Glaucoma, More than Meets the Eye: Patterns of Demyelination Revealed in Human Postmortem Glaucomatous Optic Nerve
Gabriella E. Parrilla, Akanksha Salkar, Roshana Vander Wall, Vivek Gupta, Stuart L. Graham, Yuyi You
| DOI: 10.14336/AD.2024.0336
A Framework for an Effective Healthy Longevity Clinic
Sergey Mironov, Olga Borysova, Ivan Morgunov, Zhongjun Zhou, Alexey Moskalev
| DOI: 10.14336/AD.2024.0328-1
Supplement

1. Supplementary data.pdf (502KB)

Rejuvenation Strategy for Inducing and Enhancing Autoimmune Response to Eliminate Senescent Cells
Xingyue Wang, Chengyu Zhang, Jiahong Su, Siqi Ren, Xiang Wang, Yinping Zhang, Zijun Yuan, Xinyu He, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Shuai Deng, Yueshui Zhao, Xiaodong Wang, Yuhong Sun, Jing Shen, Huijiao Ji, Yunqing Hou, Zhangang Xiao
| DOI: 10.14336/AD.2024.0579
Redefinition of Synovial Fibroblasts in Rheumatoid Arthritis
Yinci Zhang, Xiong He, Dongdong Yin, Yihao Zhang
| DOI: 10.14336/AD.2024.0514
Engineered Mitochondrial Transplantation as An Anti-Aging Therapy
Rui Zhao, Chen Dong, Qian Liang, Jianlin Gao, Chi Sun, Zhifeng Gu, Yujuan Zhu
| DOI: 10.14336/AD.2024.0231
COVID-19 and Cognitive Decline in Older Adults with High-Cardiovascular Risk: A Post Hoc Analysis
Sangeetha Shyam, Carlos Gómez-Martínez, Jiaqi Ni, José J. Gaforio, Miguel Ángel Martínez-González, Dolores Corella, J. Alfredo Martínez, Ángel M. Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J Tinahones, José Lapetra, Lluís Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Vicente Martín-Sánchez, Xavier Pintó, Miguel Delgado-Rodríguez, Pilar Matía-Martín, Josep Vidal, Clotilde Vázquez, Lidia Daimiel, Emilio Ros, Fernando Fernandez-Aranda, Adrián Hernández-Cacho, Pilar Buil-Cosiales, Jose V Sorli, Olga Castañer, Antonio Garcia-Rios, Alejandro Oncina-Canovas, Napoleón Pérez-Farinós, Mar Nafria, Rosa Casas, Silvia Martínez-Diz, Lucas Tojal-Sierra, Gómez-Pérez AM, Estefania Toledo, Rebeca Fernández-Carrión, Álvaro Morán Bayón, Jose David Torres-Peña, Laura Compañ-Gabucio, Zenaida Vázquez-Ruiz, Nancy Babio, Montserrat Fitó, Jordi Salas-Salvadó
| DOI: 10.14336/AD.2024.0380
Therapeutic Potential of Quercetin as an Antioxidant for Bone-Muscle-Tendon Regeneration and Aging
Jae Gyu Kim, Ashish Ranjan Sharma, Yeon-Hee Lee, Srijan Chatterjee, Yean Jung Choi, Roshani Rajvansh, Chiranjib Chakraborty, Sang-Soo Lee
| DOI: 10.14336/AD.2024.0282
APOE 5’UTR Methylation Pattern Analysis in Blood and Brain Tissue from Alzheimer’s Disease Affected Patients
Rosalinda Di Gerlando, Francesca Dragoni, Bartolo Rizzo, Riccardo Rocco Ferrari, Elisabetta Zardini, Matteo Cotta Ramusino, Giulia Perini, Alfredo Costa, Tino Emanuele Poloni, Orietta Pansarasa, Annalisa Davin, Stella Gagliardi
| DOI: 10.14336/AD.2024.0350
Supplement

1. Supplementary data.pdf (623KB)

Fecal Microbiota Transfer from Young Mice Reverts Vascular Aging Hallmarks and Metabolic Impairments in Aged Mice
Chak Kwong Cheng, Jun Gao, Lijing Kang, Yu Huang
| DOI: 10.14336/AD.2024.0384
Supplement

1. Supplementary data.pdf (1424KB)

The Role of the Complement System in Synaptic Pruning after Stroke
Hongying Liu, Min Jiang, Zhiying Chen, Chuan Li, Xiaoping Yin, Xiaorong Zhang, Moxin Wu
| DOI: 10.14336/AD.2024.0373
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training
Daniel G. Blackmore, Mia A. Schaumberg, Maryam Ziaei, Samuel Belford, Xuan Vinh To, Imogen O’Keeffe, Anne Bernard, Jules Mitchell, Emily Hume, Grace L. Rose, Thomas Shaw, Ashley York, Markus Barth, Elizabeth J. Cooper, Tina L. Skinner, Fatima Nasrallah, Stephan Riek, Perry F. Bartlett
| DOI: 10.14336/AD.2024.0642
Supplement

1. Supplementary data.pdf (6754KB)

Revolutionizing Senescence Detection: Advancements from Traditional Methods to Cutting-Edge Techniques
Ruopeng Xiao, Sinan Hu, Xiaohui Du, Yiwen Wang, Ke Fang, Yibin Zhu, Nanbin Lou, Chunhui Yuan, Jing Yang
| DOI: 10.14336/AD.202.0565
SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence
Alicia Villacampa, Licia Shamoon, Inés Valencia, Cristina Morales, Sofía Figueiras, Fernando de la Cuesta, Dolores Sánchez-Niño, Guillermo Díaz-Araya, Isabel Sánchez-Pérez, Carlos Félix Sánchez-Ferrer, Concepción Peiró
| DOI: 10.14336/AD.2024.0405
Supplement

1. Supplementary data.pdf (737KB)

Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov, Natasha S. Barteneva
| DOI: 10.14336/AD.2024.0526
Crosstalk between Circadian Rhythm Dysregulation and Tumorigenesis, Tumor Metabolism and Tumor Immune Response
Yifei Zhu, Yao Zheng, Rongyu Dai, Xuyu Gu
| DOI: 10.14336/AD.2024.0533
Gut Microbiota and Its Metabolites: The Emerging Bridge Between Coronary Artery Disease and Anxiety and Depression?
Haiyang Chen, Lijun Zhang, Yanwei Li, Xiangxi Meng, Yunpeng Chi, Meiyan Liu
| DOI: 10.14336/AD.2024.0538
Aging and “Age-Related” Diseases - What Is the Relation?
Wolfgang Kopp
| DOI: 10.14336/AD.2024.0570
Exercise-Induced Central Fatigue: Biomarkers, and Non-Medicinal Interventions
Ying Yang, Zhi Feng, Yu-hang Luo, Jue-miao Chen, Yu Zhang, Yi-jun Liao, Hui Jiang, Yinxi Long, Bo Wei
| DOI: 10.14336/AD.2024.0567
Environmental and Climate Impacts on Physiological Aging: Comprehensive Pathways to Enhanced Age-related Resilience
Chengmeng Zhang, Shangjun Liu, Gong Chen
| DOI: 10.14336/AD.2024.0478
Delaying Renal Aging: Metformin Holds Promise as a Potential Treatment
Qiao Zheng, Jin Zhao, Jinguo Yuan, Yunlong Qin, Zhanxin Zhu, Jie Liu, Shiren Sun
| DOI: 10.14336/AD.2024.0168
Establishing Predictors of Acute Sarcopenia: A Proof-Of-Concept Study Utilising Network Analysis
Carly Welch, Laura Bravo, Georgios Gkoutos, Carolyn Greig, Danielle Lewis, Janet Lord, Zeinab Majid, Tahir Masud, Kirsty McGee, Hannah Moorey, Thomas Pinkney, Benjamin Stanley, Thomas Jackson
| DOI: 10.14336/AD.2024.0167
Supplement

1. Supplementary data.pdf (766KB)

Dysregulation of Lipid Metabolism Serves as A Link Between Alzheimer’s and Cardiovascular Disease, As Witnessed in A Cross-Sectional Study
Laura Mourino-Alvarez, Cristina Juarez-Alia, Tamara Sastre-Oliva, Inés Perales-Sánchez, German Hernandez-Fernandez, Eduardo Chicano-Galvez, Ángela Peralbo-Molina, Felipe Madruga, Emilio Blanco-Lopez, Teresa Tejerina, María G. Barderas
| DOI: 10.14336/AD.2024.0434
Supplement

1. Supplementary data.pdf (391KB)

Expert Consensus on the Application of Stem Cells in Psoriasis Research and Clinical Trials
Ye-Hong Kuang, Wu Zhu, Ge Lin, La-Mei Cheng, Qun Qin, Zhi-Jun Huang, Yu-Ling Shi, Chun-Lei Zhang, Jin-Hua Xu, Ke-Xiang Yan, Cheng-Zhi Lv, Wei Li, Qin Han, Ilia Stambler, Lee Wei Lim, Sasanka Chakrabarti, Brun Ulfhake, Kyung-Jin Min, Georgina Ellison-Hughes, William C Cho, Kunlin Jin, Danni Yao, Chuanjian Lu, Robert Chunhua Zhao, Xiang Chen
| DOI: 10.14336/AD.2024.0012
Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer’s Disease
Temitope Adeoye, Syed I Shah, Ghanim Ullah
| DOI: 10.14336/AD.2024.0429
Supplement

1. Supplementary data.pdf (1018KB)

ATF4 Contributes to Abdominal Aortic Aneurysm Formation via Modulating M1 Macrophage Polarization and Inflammation
Huahui Yu, Xiaolu Jiao, Qianwen Lv, Linyi Li, Yunhui Du, Chaowei Hu, Zhiyong Du, Fan Li, Yu Wang, Xiaoqian Gao, Lijie Han, Xuechun Sun, Dong Chen, Yanwen Qin
| DOI: 10.14336/AD.2024.0116
Cellular Senescence in Acute Liver Injury: What Happens to the Young Liver?
Keting He, Diwenxin Zhou, Zhangya Pu, Shangci Chen, Yangfan Shen, Shuai Zhao, Xiaohan Qian, Qingqing Hu, Xiaoxin Wu, Zhongyang Xie, Xiaowei Xu
| DOI: 10.14336/AD.2024.0586
Conflict-Related Breakdowns in Routine Medical Care - Longitudinal Outcomes for Civilians with Pre-Existing Cognitive Impairment
Zorian Radomyslsky, Sara Kivity, Yaniv Alon, Mor Saban
| DOI: 10.14336/AD.2024.0432
Supplement

1. Supplementary data.pdf (557KB)

Senescent Astrocytes Derived from Human Pluripotent Stem Cells Reveal Age-Related Changes and Implications for Neurodegeneration
Dongyun Kim, Seo Hyun Yoo, Gyu-Bum Yeon, Seung Soo Oh, Won-Ho Shin, Hoon-Chul Kang, Cheol-Koo Lee, Hyung Wook Kim, Dae-Sung Kim
| DOI: 10.14336/AD.2024.0089
Supplement

1. Supplementary data.pdf (1310KB)

Mind the Metabolic Gap: Bridging Migraine and Alzheimer's disease through Brain Insulin Resistance
Lorenzo Del Moro, Elenamaria Pirovano, Eugenia Rota
| DOI: 10.14336/AD.2024.0351
Brain Iron Dyshomeostasis and Ferroptosis in Alzheimer’s Disease Pathophysiology: Two Faces of the Same Coin
Mariarosa Mezzanotte, Serena Stanga
| DOI: 10.14336/AD.2024.0094
Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions
Piotr Paweł Chmielewski, Krzysztof Data, Bartłomiej Strzelec, Maryam Farzaneh, Amir Anbiyaiee, Uzma Zaheer, Shahab Uddin, Mohadeseh Sheykhi-Sabzehpoush, Paul Mozdziak, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempisty
| DOI: 10.14336/AD.2024.0280
Treatment of Rheumatoid Arthritis Based on the Inherent Bioactivity of Black Phosphorus Nanosheets
Cheng Zhuang, Ruiqi Sun, Yuchen Zhang, Qing Zou, Jianxin Zhou, Naijun Dong, Xuyu Zhao, Wenjun Fu, Xiaoke Geng, Jiao Wang, Qian Li, Robert Chunhua Zhao
| DOI: 10.14336/AD.2024.0319
Supplement

1. Supplementary data.pdf (1063KB)

Ovariectomy and High Fat-Sugar-Salt Diet Induced Alzheimer's Disease/Vascular Dementia Features in Mice
Sahar Sweetat, Moti Ben Shabat, Paschalis Theotokis, Nir Suissa, Eleni Karafoulidou, Olga Touloumi, Rami Abu-Fanne, Oded Abramsky, Gilly Wolf, Ann Saada, Amit Lotan, Nikolaos Grigoriadis, Hanna Rosenmann
| DOI: 10.14336/AD.2024.03110
Neuroanatomical Signature of the Transition from Normal Cognition to MCI in Parkinson's Disease
Iman Beheshti, Jarrad Perron, Ji Hyun Ko
| DOI: 10.14336/AD.2024.0323
Aging and Autophagy: Roles in Musculoskeletal System Injury
Haifeng Zhang, Wenhui Gu, Genbin Wu, Yinxian Yu
| DOI: 10.14336/AD.2024.0362
Cellular Aging and Senescence in Cancer: A Holistic Review of Cellular Fate Determinants
Muhammad Tufail, Yu-Qi Huang, Jia-Ju Hu, Jie Liang, Cai-Yun He, Wen-Dong Wan, Can-Hua Jiang, Hong Wu, Ning Li
| DOI: 10.14336/AD.2024.0421
Targeting the Ophthalmic Diseases Using Extracellular Vesicles ‘Exosomes’: Current Insights on Their Clinical Approval and Present Trials
Hanxiang Yu, Jinsong Wu, Gaoxiang Pan
| DOI: 10.14336/AD.2024.0535
Nogo-A Drives Alzheimer’s Disease Progression by Inducing Tauopathy Vulnerability
Zijian Wang, Jun-ping Pan, Jiayuan Geng, Shijie Lv, Guisi Chen, Nian Fang, Zheng Zhang, Junliang Li, Xinke Xu, Rui Wang, Qing Zheng, Li Yan, Guobing Chen, Fei Xiao
| DOI: 10.14336/AD.2024.0053
Supplement

1. Supplementary data.pdf (888KB)

Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential
Qianting Deng, Emily Parker, Chongyun Wu, Ling Zhu, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
| DOI: 10.14336/AD.2024.0239