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2022
Impact Factor
7.4

Early Edition

The papers published below have been examined by the peer-review process and accepted for publication in Aging and Disease. A “Just Accepted” paper is published online shortly after its acceptance, which allows authors to make their results available to the research community as soon as possible after acceptance. When the final version appears, the version of early edition is replaced with the final version, and the paper is moved to the appropriate issue on the Aging and Disease website. The paper will no longer appear in the “Just Accepted”. However, all links (the URL) will not change. “Just Accepted” papers are citable from that date they are posted. To cite this manuscript please include its Digital Object Identifier (DOI), which is identical for all formats of publication.
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Total 160 results are found
Mind the Metabolic Gap: Bridging Migraine and Alzheimer's disease through Brain Insulin Resistance
Lorenzo Del Moro, Elenamaria Pirovano, Eugenia Rota
| DOI: 10.14336/AD.2024.0351
Brain Iron Dyshomeostasis and Ferroptosis in Alzheimer’s Disease Pathophysiology: Two Faces of the Same Coin
Mariarosa Mezzanotte, Serena Stanga
| DOI: 10.14336/AD.2024.0094
Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions
Piotr Paweł Chmielewski, Krzysztof Data, Bartłomiej Strzelec, Maryam Farzaneh, Amir Anbiyaiee, Uzma Zaheer, Shahab Uddin, Mohadeseh Sheykhi-Sabzehpoush, Paul Mozdziak, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempisty
| DOI: 10.14336/AD.2024.0280
Treatment of Rheumatoid Arthritis Based on the Inherent Bioactivity of Black Phosphorus Nanosheets
Cheng Zhuang, Ruiqi Sun, Yuchen Zhang, Qing Zou, Jianxin Zhou, Naijun Dong, Xuyu Zhao, Wenjun Fu, Xiaoke Geng, Jiao Wang, Qian Li, Robert Chunhua Zhao
| DOI: 10.14336/AD.2024.0319
Supplement

1. Supplementary data.pdf (1063KB)

Ovariectomy and High Fat-Sugar-Salt Diet Induced Alzheimer's Disease/Vascular Dementia Features in Mice
Sahar Sweetat, Moti Ben Shabat, Paschalis Theotokis, Nir Suissa, Eleni Karafoulidou, Olga Touloumi, Rami Abu-Fanne, Oded Abramsky, Gilly Wolf, Amit Lotan, Nikolaos Grigoriadis, Hanna Rosenmann
| DOI: 10.14336/AD.2024.03110
Neuroanatomical Signature of the Transition from Normal Cognition to MCI in Parkinson's Disease
Iman Beheshti, Jarrad Perron, Ji Hyun Ko
| DOI: 10.14336/AD.2024.0323
Aging and Autophagy: Roles in Musculoskeletal System Injury
Haifeng Zhang, Wenhui Gu, Genbin Wu, Yinxian Yu
| DOI: 10.14336/AD.2024.0362
Cellular Aging and Senescence in Cancer: A Holistic Review of Cellular Fate Determinants
Muhammad Tufail, Yu-Qi Huang, Jia-Ju Hu, Jie Liang, Cai-Yun He, Wen-Dong Wan, Can-Hua Jiang, Hong Wu, Ning Li
| DOI: 10.14336/AD.2024.0421
Targeting the Ophthalmic Diseases Using Extracellular Vesicles ‘Exosomes’: Current Insights on Their Clinical Approval and Present Trials
Hanxiang Yu, Jinsong Wu, Gaoxiang Pan
| DOI: 10.14336/AD.2024.0535
Nogo-A Drives Alzheimer’s Disease Progression by Inducing Tauopathy Vulnerability
Zijian Wang, Jun-ping Pan, Jiayuan Geng, Shijie Lv, Guisi Chen, Nian Fang, Zheng Zhang, Junliang Li, Xinke Xu, Rui Wang, Qing Zheng, Li Yan, Guobing Chen, Fei Xiao
| DOI: 10.14336/AD.2024.0053
Supplement

1. Supplementary data.pdf (888KB)

Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential
Qianting Deng, Emily Parker, Chongyun Wu, Ling Zhu, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
| DOI: 10.14336/AD.2024.0239
Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects
Ting Shen, Samran Sheriff, Yuyi You, Jiyang Jiang, Angela Schulz, Heather Francis, Mehdi Mirzaei, Danit Saks, Viswanthram Palanivel, Devaraj Basavarajappa, Nitin Chitranshi, Veer Gupta, Wei Wen, Perminder S. Sachdev, Huixun Jia, Xiaodong Sun, Stuart L. Graham, Vivek K. Gupta
| DOI: 10.14336/AD.2024.0346
Supplement

1. Supplementary data.pdf (171KB)

Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic Hypoperfusion
Jeffrey Thompson, Yirong Yang, Kelsey Duval, Michael Griego, Haojie Chen, Karen SantaCruz, Haoran Deng, Carlos Perez, Sean Maez, Sasha Hobson, Theodore Li, Halima Akter, Michel Torbey, Yi Yang
| DOI: 10.14336/AD.2024.0098
The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging
Mulin Xu, Xiuxian Wei, Jinli Wang, Yi Li, Yi Huang, Anying Cheng, Fan He, Le Zhang, Cuntai Zhang, Yu Liu
| DOI: 10.14336/AD.2024.0075
Supplement

1. Supplementary data.pdf (1137KB)

m6A Reader HNRNPC Facilitates Adipogenesis by Regulating Cytoskeletal Remodeling through Enhanced Lcp1 mRNA Stability
Wenhua Xie, Yewei Cui, Lingzhi Yue, Ting Zhang, Chenglong Huang, Xinyu Yu, Dan Ma, Dongfang Liu, Rui Cheng, Xueya Zhao, Xi Li
| DOI: 10.14336/AD.2024.0132
Supplement

1. Supplementary data.pdf (900KB)

Assessing the Influence of Maternal Age in Bovine Embryos and Oocytes: A Model for Human Reproductive Aging
Aleksander Franciszek Butkiewicz, Ana Amaral, Marta Cerveira-Pinto, Pawel Kordowitzki
| DOI: 10.14336/AD.2024.0305
Adiponectin mRNA Conjugated with Lipid Nanoparticles Specifically Targets the Pathogenesis of Type 2 Diabetes
Rady E. El-Araby, Qisheng Tu, Ying Xie, Tarek Aboushousha, Zhongyu Li, Xiaoyang Xu, Zoe X. Zhu, Lily Q. Dong, Jake Chen
| DOI: 10.14336/AD.2024.0162
Supplement

1. Supplementary data.pdf (275KB)

Deep Learning Based on Computed Tomography Predicts Response to Chemoimmunotherapy in Lung Squamous Cell Carcinoma
Jie Peng, Baowen Xie, Honglian Ma, Rui Wang, Xiao Hu, Zhongjun Huang
| DOI: 10.14336/AD.2024.0169
Supplement

1. Supplementary data.pdf (676KB)

Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies
Xin-ran Zhao, Jia-bin Zong, Yu-xiao Liu, Tuersun Aili, Min Qiu, Jie-hong Wu, Bo Hu
| DOI: 10.14336/AD.2024.0123-1
Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis
Lushuang Xie, Qiaofeng Wu, Kelin Li, Mohammed A. S. Khan, Andrew Zhang, Bharati Sinha, Sihui Li, Sulie L. Chang, David L. Brody, Mark W. Grinstaff, Shuanhu Zhou, Gil Alterovitz, Pinghua Liu, Xin Wang
| DOI: 10.14336/AD.2024.0134
Association between Body Iron Status and Cognitive Task Performance in a Nationally Representative Sample of Older Adults
Jianying Peng, Buyun Liu, Wei Tan, Shouzhang Hu, Benchao Li, Jin Zhou, Guifeng Xu, Yangbo Sun, Linda G. Snetselaar, Robert B. Wallace, Shuang Rong, Wei Bao
| DOI: 10.14336/AD.2019.0064
Supplement

1. Supplementary data.pdf (382KB)

Mitochondrial Dysfunction: A Roadmap for Understanding and Tackling Cardiovascular Aging
Han Zhang, Mairedan Muhetarijiang, Ryan J. Chen, Xiaosheng Hu, Jie Han, Liangrong Zheng, Ting Chen
| DOI: 10.14336/AD.2024.0058
Inferior Frontal Sulcal Hyperintensity on Fluid-Attenuated Inversion Recovery Is Related to Cerebrospinal Fluid Clearance via Putative Meningeal Lymphatics
Ziyu Zhou, Ying Zhou, Wang Ran, Shenqiang Yan, Xiao Zhu, Zhongyu Luo, Huihong Ke, Kemeng Zhang, Mengmeng Fang, Jianzhong Sun, Min Lou
| DOI: 10.14336/AD.2024.0415
Supplement

1. Supplementary data.pdf (322KB)

Expert Consensus on Prevention and Treatment of Aging-Related Gonadal Dysfunction
Xi Wang, Li Ma, Sheng Jiang, Junping Wen, Zhaoli Yan, Long Tian, Shan Deng, Boxian Huang, Ilia Stambler, Calogero Caruso, Kyung-Jin Min, Huanxing Su, Kunlin Jin, Jiangfeng Mao, Xueyan Wu, Qin Han, Robert Chunhua Zhao
| DOI: 10.14336/AD.2024.0004
Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis
Jiaqi Xin, Sen Huang, Jing Wen, Yunhao Li, Ang Li, Senthil Kumaran Satyanarayanan, Xiaoli Yao, Huanxing Su
| DOI: 10.14336/AD.2024.0440
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
| DOI: 10.14336/AD.2024.0083
The Role of Liquid‒Liquid Phase Separation in the Accumulation of Pathological Proteins: New Perspectives on the Mechanism of Neurodegenerative Diseases
Xingyu Lu, Jiongtong Lu, Shengnan Li, Sifan Feng, Yan Wang, Lili Cui
| DOI: 10.14336/AD.2024.0209
Vascular Calcification Heterogeneity from Bench to Bedside: Implications for Manifestations, Pathogenesis, and Treatment Considerations
Kuo-Cheng Lu, Kuo-Chin Hung, Min-Tser Liao, Li-Jane Shih, Chia-Ter Chao
| DOI: 10.14336/AD.2024.0289
Amyloid-β and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer’s Disease
Jangampalli Adi Pradeepkiran, Javaria Baig, Md Ariful Islam, Sudhir Kshirsagar, P. Hemachandra Reddy
| DOI: 10.14336/AD.2024.0286
The Role of Protein S-Nitrosylation in Mitochondrial Quality Control in Central Nervous System Diseases
Fang Qiu, Yuqiang Liu, Zhiheng Liu
| DOI: 10.14336/AD.2024.0099
A Comprehensive Prediction Model for Futile Recanalization in AIS Patients Post-Endovascular Therapy: Integrating Clinical, Imaging, and No-Reflow Biomarkers
Shuangfeng Huang, Jiali Xu, Haijuan Kang, Wenting Guo, Changhong Ren, Alexandra Wehbe, Haiqing Song, Qingfeng Ma, Wenbo Zhao, Yuchuan Ding, Xunming Ji, Sijie Li
| DOI: 10.14336/AD.2024.0127
Supplement

1. Supplementary data.pdf (155KB)

Age-Related Changes in the Glycolytic Enzymes of M2-Isoform of Pyruvate Kinase and Fructose-1,6-Bisphosphate Aldolase: Implications to Age-Related Macular Degeneration
Ammaji Rajala, Raju V. S. Rajala
| DOI: 10.14336/AD.2024.0077
Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment
Yiming Pan, Lina Ma
| DOI: 10.14336/AD.2024.0258
Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
Guiqin Zhang, Priyadarshani Nadeeshika Samarawickrama, Li Gui, Yuan Ma, Mei Cao, Hong Zhu, Wei Li, Honglin Yang, Kecheng Li, Yang Yang, Enfang Zhu, Wen Li, Yonghan He
| DOI: 10.14336/AD.2024.0065
Skin-brain axis in Alzheimer's disease - Pathologic, diagnostic, and therapeutic implications: A Hypothetical Review
Hyeon soo Kim, Haram Jung, Yong Ho Park, Su-Hak Heo, Sujin Kim, Minho Moon
| DOI: 10.14336/AD.2024.0406
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies
Yonglian Chen, Jinhui Wu
| DOI: 10.14336/AD.2024.0407
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice
Mengpei Zhu, Yumei Huang, Ziwen Wang, Ze Jin, Jiali Cao, Qiangqiang Zhong, Zhifan Xiong
| DOI: 10.14336/AD.2024.0321
Supplement

1. Supplementary data.pdf (500KB)

Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer
Guanhua Yi, Haixin Luo, Yalin Zheng, Wenjing Liu, Denian Wang, Yong Zhang
| DOI: 10.14336/AD.2024.0409
Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
| DOI: 10.14336/AD.2024.0331
Current Understanding of Marginal Grafts in Liver Transplantation
Ze Xiang, Jiarui Li, Huixuan Zeng, Xiaonan Xiang, Fengqiang Gao, Kai Wang, Xuyong Wei, Shusen Zheng, Xiao Xu
| DOI: 10.14336/AD.2024.0214