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2022
Impact Factor
7.4

Early Edition

The papers published below have been examined by the peer-review process and accepted for publication in Aging and Disease. A “Just Accepted” paper is published online shortly after its acceptance, which allows authors to make their results available to the research community as soon as possible after acceptance. When the final version appears, the version of early edition is replaced with the final version, and the paper is moved to the appropriate issue on the Aging and Disease website. The paper will no longer appear in the “Just Accepted”. However, all links (the URL) will not change. “Just Accepted” papers are citable from that date they are posted. To cite this manuscript please include its Digital Object Identifier (DOI), which is identical for all formats of publication.
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Total 130 results are found
Mesenchymal Stem Cells-based Cell-free Therapy Targeting Neuroinflammation
Hongjie Xu, Bin Wang, Ang Li, Jing Wen, Huanxing Su, Dajiang Qin
| DOI: 10.14336/AD.2023.0904
Erratum to “NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice”
Annadurai Anandhan, Nhat Nguyen, Arjun Syal, Luke A Dreher, Matthew Dodson, Donna D. Zhang, Lalitha Madhavan
| DOI: 10.14336/AD.2023.10917
Autophagy in Disease Onset and Progression
Hao Wang, Xiushen Li, Qi Zhang, Chengtao Fu, Wenjie Jiang, Jun Xue, Shan Liu, Qingxue Meng, Lisha Ai, Xuejun Zhi, Shoulong Deng, Weizheng Liang
| DOI: 10.14336/AD.2023.0815
A new immunological index for the elderly: high proportion of multiple TCR T cells based on scRNA-seq
Li Jun, Zhu Lanwei, Wang Jiayi, Yao Xinsheng
| DOI: 10.14336/AD.2023.0509-1
Supplement

1. Supplementary data.pdf (130KB)

Semaphorins: Missing Signals in Age-dependent Alteration of Neuromuscular Junctions and Skeletal Muscle Regeneration
Damon Fard, Alessandra Barbiera, Gabriella Dobrowolny, Luca Tamagnone, Bianca Maria Scicchitano
| DOI: 10.14336/AD.2023.0801
Age-Related Alterations in Immune Function and Inflammation: Focus on Ischemic Stroke
Qiuxin Chen, Minmin Wu, Qiang Tang, Peiyu Yan, Luwen Zhu
| DOI: 10.14336/AD.2023.0721-1
Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection
Stefanie Deinhardt-Emmer, Sharvari Deshpande, Koji Kitazawa, Allison B. Herman, Joanna Bons, Jacob P. Rose, Prasanna Ashok Kumar, Carlos Anerillas, Francesco Neri, Serban Ciotlos, Kevin Perez, Nilay Köse-Vogel, Antje Häder, Kotb Abdelmohsen, Bettina Löffler, Myriam Gorospe, Pierre-Yves Desprez, Simon Melov, David Furman, Birgit Schilling, Judith Campisi
| DOI: 10.14336/AD.2023.0812
Supplement

1. Supplementary data.pdf (531KB)

A Population-Based Scoring System to Assess the Impact of Individual Risk Factors on Vascular Health
Vanessa Gagliano, David Gehrig, Rosaria Del Giorno, Jvan Gianini, Luca Gabutti
| DOI: 10.14336/AD.2023.0823
Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals
Cyrus A. Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala
| DOI: 10.14336/AD.2023.0820
Astrocyte-Derived Extracellular Vesicles for Ischemic Stroke: Therapeutic Potential and Prospective
Xianghui Wang, Aihua Li, Huaju Fan, Yanyan Li, Nana Yang, Yaohui Tang
| DOI: 10.14336/AD.2023.0823-1
Perspectives on Osteoarthritis Treatment with Mesenchymal Stem Cells and Radix Achyranthis Bidentatae
Xingyan An, Jiao Wang, Ke Xu, Robert Chunhua Zhao, Jiacan Su
| DOI: 10.14336/AD.2023.0817
Pericyte Dysfunction Contributes to Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats
Siyang Lin, Benjamin Landon, Hongxia Zhang, Kunlin Jin
| DOI: 10.14336/AD.2023.0821-1
Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential
Linkai Qu, Yanwei Li, Fan Liu, Yimeng Fang, Jiaxuan He, Jiahui Ma, Ting Xu, Lei Wang, Pengyu Lei, Hao Dong, Libo Jin, Qinsi Yang, Wei Wu, Da Sun
| DOI: 10.14336/AD.2023.0823-2
Crosstalk among Reactive Oxygen Species, Autophagy and Metabolism in Myocardial Ischemia and Reperfusion Stages
Yajie Peng, Yachuan Tao, Lingxu Liu, Ji Zhang, Bo Wei
| DOI: 10.14336/AD.2023.0823-4
Glycometabolic Reprogramming of Microglia in Neurodegenerative Diseases: Insights from Neuroinflammation
Qi Huang, Yanfu Wang, Shanshan Chen, Fengxia Liang
| DOI: 10.14336/AD.2023.0807
Extracellular MicroRNAs as Potential Biomarkers for Frail Kidney Phenotype: Progresses and Precautions
Chia-Ter Chao, Chih-Kang Chiang, Kuan-Yu Hung
| DOI: 10.14336/AD.2023.0818
M2 Microglial Extracellular Vesicles Attenuated Blood-brain Barrier Disruption via MiR-23a-5p in Cerebral Ischemic Mice
Jia-Ji Pan, Lin Qi, Liping Wang, Chang Liu, Yaying Song, Muyassar Mamtilahun, Xiaowen Hu, Yongfang Li, Xiao Chen, Haroon Khan, Qun Xu, Yongting Wang, Yaohui Tang, Guo-Yuan Yang, Zhijun Zhang
| DOI: 10.14336/AD.2023.0714
State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease
Elizabeth M. Rhea, Manon Leclerc, Hussein N. Yassine, Ana W. Capuano, Han Tong, Vladislav A. Petyuk, Shannon L. Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis
| DOI: 10.14336/AD.2023.0814
Microglia Autophagy Mediated by TMEM166 Promotes Ischemic Stroke Secondary to Carotid Artery Stenosis
Li Li, Paul R. Krafft, Na Zeng, Ranran Duan, Xiang Qi, Anwen Shao, Fushan Xue, John H. Zhang
| DOI: 10.14336/AD.2023.0803
Supplement

1. Supplementary data.pdf (549KB)

Contribution of Direct Cerebral Vascular Transport in Brain Substance Clearance
Qiuting Wen, Haoyu Wang, E. Mark Haacke, Quan Jiang, Jiani Hu
| DOI: 10.14336/AD.2023.0426
Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency
Feiyan Zhao, Long Yan, Xuehan Zhao, Jiaqi Wu, Ying Fang, Zhimin Xin, Hongmei Wang, Xiaokui Yang
| DOI: 10.14336/AD.2023.0809
Supplement

1. Supplementary data.pdf (881KB)

Biomarkers of Aging and Relevant Evaluation Techniques: A Comprehensive Review
Xue Tao, Ziman Zhu, Liguo Wang, Chunlin Li, Liwei Sun, Wei Wang, Weijun Gong
| DOI: 10.14336/AD.2023.00808-1
The Importance of Venous Reflux Status Evaluation in the Intensive Care Unit
Hua Zhao, Beijun Gao, Hongmin Zhang, Xiaoting Wang, Critical Care Ultrasound Study Group*
| DOI: 10.14336/AD.2023.0731
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
| DOI: 10.14336/AD.2023.0707-1
Supplement

1. Supplementary data.pdf (2374KB)

Endogenous Alpha-Synuclein is Essential for the Transfer of Pathology by Exosome-Enriched Extracellular Vesicles, Following Inoculation with Preformed Fibrils in vivo
Katerina Melachroinou, Georgios Divolis, George Tsafaras, Mantia Karampetsou, Sotirios Fortis, Yannis Stratoulias, Gina Papadopoulou, Anastasios G. Kriebardis, Martina Samiotaki, Kostas Vekrellis
| DOI: 10.14336/AD.2023.0614
Supplement

1. Supplementary data.pdf (3194KB)

Shedding Light on the Interaction Between Rif1 and Telomeres in Ovarian Cancer
Paweł Kordowitzki, Szymon Graczyk, Sylvia Mechsner, Jalid Sehouli
| DOI: 10.14336/AD.2023.0716
Alzheimer Disease Pathology and Neurodegeneration in Midlife Obesity: A Pilot Study
Mahsa Dolatshahi, Paul K. Commean, Farzaneh Rahmani, Jingxia Liu, LaKisha Lloyd, Caitlyn Nguyen, Nancy Hantler, Maria Ly, Gary Yu, Joseph E. Ippolito, Claude Sirlin, John C. Morris, Tammie L.S. Benzinger, Cyrus A. Raji
| DOI: 10.14336/AD.2023.0707
Supplement

1. Supplementary data.pdf (178KB)

Synergistically Acting on Myostatin and Agrin Pathways Increases Neuromuscular Junction Stability and Endurance in Old Mice
Roberta Schellino, Marina Boido, Jan W. Vrijbloed, Ruggero G. Fariello, Alessandro Vercelli
| DOI: 10.14336/AD.2023.0713-1
Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia
Wenze Deng, Pengcheng Yi, Yanhong Xiong, Jun Ying, Yue Lin, Yao Dong, Gen Wei, Xifeng Wang, Fuzhou Hua
| DOI: 10.14336/AD.2023.0727
Mitochondria-mediated Ferroptosis in Diseases Therapy: From Molecular Mechanisms to Implications
Fuhai Feng, Shasha He, Xiaoling Li, Jiake He, Lianxiang Luo
| DOI: 10.14336/AD.2023.0717
Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Sajid Ur Rahman, Abdul Qadeer, Ziyun Wu
| DOI: 10.14336/AD.2023.0519-1
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung
Claudia F. Garcia Castro, Claudio Nardiello, Stefan Hadzic, Baktybek Kojonazarov, Simone Kraut, Mareike Gierhardt, Julia Schäffer, Mariola Bednorz, Karin Quanz, Jacqueline Heger, Martina Korfei, Jochen Wilhelm, Matthias Hecker, Marek Bartkuhn, Stefan Arnhold, Andreas Guenther, Werner Seeger, Rainer Schulz, Norbert Weissmann, Natascha Sommer, Oleg Pak
| DOI: 10.14336/AD.2023.0715
Supplement

1. Supplementary data.pdf (698KB)

The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Yang Yu, Ran Chen, Kaiyue Mao, Maoyan Deng, Zhigang Li
| DOI: 10.14336/AD.2023.0718
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway
Ruoyan Xue, Mengyao Xie, Zhiyuan Wu, Shu Wang, Yongli Zhang, Zhijin Han, Chen Li, Qi Tang, Liping Wang, Di Li, Shihua Wang, Hua Yang, Robert Chunhua Zhao
| DOI: 10.14336/AD.2023.0719-1
Supplement

1. Supplementary data.pdf (505KB)

Myelin Pathology in Alzheimer's Disease: Potential Therapeutic Opportunities
Zhihai Huang, J. Dedrick Jordan, Quanguang Zhang
| DOI: 10.14336/AD.2023.0628
“Post-Protean” Public Health and the Geroscience Hypothesis
Colin Farrelly
| DOI: 10.14336/AD.2023.0721
Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation
Yu Chen, Junren Chen, Ziwei Xing, Cheng Peng, Dan Li
| DOI: 10.14336/AD.2023.0718-1
Altered Osteoblast Metabolism with Aging Results in Lipid Accumulation and Oxidative Stress Mediated Bone Loss
Ananya Nandy, Alison Richards, Santosh Thapa, Alena Akhmetshina, Nikita Narayani
| DOI: 10.14336/AD.2023.0510
Supplement

1. Supplementary data.pdf (1526KB)

Differential Effects of Endurance Exercise on Musculoskeletal and Hematopoietic Modulation in Old Mice
Zilin Wang, Hyun-Jaung Sim, Wenduo Liu, Jae Cheol Kim, Jeong-Chae Lee, Sung-Ho Kook, Sang Hyun Kim
| DOI: 10.14336/AD.2023.0713
Aging, Cellular Senescence, and Glaucoma
Yumeng Zhang, Shouyue Huang, Bing Xie, Yisheng Zhong
| DOI: 10.14336/AD.2023.0631