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2022
Impact Factor
7.4

Early Edition

The papers published below have been examined by the peer-review process and accepted for publication in Aging and Disease. A “Just Accepted” paper is published online shortly after its acceptance, which allows authors to make their results available to the research community as soon as possible after acceptance. When the final version appears, the version of early edition is replaced with the final version, and the paper is moved to the appropriate issue on the Aging and Disease website. The paper will no longer appear in the “Just Accepted”. However, all links (the URL) will not change. “Just Accepted” papers are citable from that date they are posted. To cite this manuscript please include its Digital Object Identifier (DOI), which is identical for all formats of publication.
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Total 146 results are found
Ocular delivery of Pigment Epithelium-Derived Factor (PEDF) as a neuroprotectant for Geographic Atrophy
Emily F. Warner, Laura Vaux, Kara Boyd, Peter S. Widdowson, Katie M. Binley, Andrew Osborne
| DOI: 10.14336/AD.2024.0216-1
A Neglected Gene: The Role of the ANG Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis
Yu Zhang, Yanan Li, Shen Bin, Xi Cheng, Qi Niu
| DOI: 10.14336/AD.2024.0107
Orthostatic Hypotension and Cognitive Function in Individuals 85 Years of Age: A Longitudinal Cohort Study in Sweden
Peder af Geijerstam, Katie Harris, Maria M. Johansson, John Chalmers, Katarina Nägga, Karin Rådholm
| DOI: 10.14336/AD.2024.0205
Supplement

1. Supplementary data.pdf (402KB)

Nanomaterials in Medicine: Understanding Cellular Uptake, Localization, and Retention for Enhanced Disease Diagnosis and Therapy
Yue Peng, Zhengshuang Yang, Hui Sun, Jinling Li, Xiuwan Lan, Sijia Liu
| DOI: 10.14336/AD.2024.0206-1
The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds
Wenjie He, Ming Tang, Rifang Gu, Xingqian Wu, Xinrui Mu, Xuqiang Nie
| DOI: 10.14336/AD.2024.0212
Mortality Outcomes in a Large Population with and without Covert Cerebrovascular Disease
Úna Clancy, Eric J. Puttock, Wansu Chen, William Whiteley, Ellen M. Vickery, Lester Y. Leung, Patrick H. Luetmer, David F. Kallmes, Sunyang Fu, Chengyi Zheng, Hongfang Liu, David M. Kent
| DOI: 10.14336/AD.2024.0211
Supplement

1. Supplementary data.pdf (589KB)

The Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression
Xiang Li, Yuchuan Ding, Yazeed W. Haddad, Xiaokun Geng
| DOI: 10.14336/AD.2024.0213
Cell Reprogramming Strategies for Treating Osteoarthritis and Intervertebral Disc Degeneration
Zhengfa Jiang, Chen Cao, Yuhao Zhang, Miaoheng Yan, Zongmian Song, Guowei Shang, Hongwei Kou, Hongjian Liu, Yusheng Li, Songfeng Chen
| DOI: 10.14336/AD.2023.1224
Elevated CD4+ T Cell Senescence Associates with Impaired Immune Responsiveness in Severe COVID-19
Jie Zhang, Chun Chang, Zhaoyuan Liang, Tingting Hu, Zhongnan Yin, Ying Liang, Ting Zhang, Yanling Ding, Xianlong Li, Xiaoyan Gai, Xiaoxue Yang, Xin Li, Xixuan Dong, Jiaqi Ren, Yafei Rao, Jun Wang, Jianling Yang, Lixiang Xue, Yongchang Sun
| DOI: 10.14336/AD.2024.0214-2
Supplement

1. Supplementary data.pdf (1269KB)

Physical Exercise Counteracts Aging-Associated White Matter Demyelination Causing Cognitive Decline
Tanya H. Butt, Makoto Tobiume, Diane B. Re, Shingo Kariya
| DOI: 10.14336/AD.2024.0216
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization
Tian Zeng, Yiqun Chen, Honghao Huang, Shengqi Li, Jiaqi Huang, Haobo Xie, Shenyi Lin, Siyao Chen, Guangyong Chen, Dehao Yang
| DOI: 10.14336/AD.2024.0131-1
Lipid Droplets Accumulation in the Brain of HIV Transgenic Rat: Implication in the Accelerated Aging of HIV Infected Individuals
Ming-Lei Guo, Yan Cheng, Damian Martinez Pineda, Rachael E. Dempsey, Lifang Yang
| DOI: 10.14336/AD.2024.0125
A Dual-Task Paradigm Combining Physical and Cognitive Training in Mice: Application to Aging
Elpidio Attoh-Mensah, Antoine Huret, Marianne Leger, Gilles Loggia, Gerald Nee, Stacy Largilliere, Daniel Zuba, Chantal Chavoix, Pascale Schumann-Bard, Thomas Freret
| DOI: 10.14336/AD.2024.0207-1
Inflammatory Pathogenesis of Post-stroke Depression
Xinyu Feng, Xiaojuan Ma, Juan Li, Qing Zhou, Yao Liu, Jingyi Song, Jiaqi Liu, Qingqing Situ, Lingyue Wang, Jingzhi Zhang, Facai Lin
| DOI: 10.14336/AD.2024.0203
Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke
Zhifang Li, Shuai Sun, Qinghui Xiao, Senwei Tan, Huijuan Jin, Bo Hu
| DOI: 10.14336/AD.2024.0204-1
Supplement

1. Supplementary data.pdf (624KB)

Association of Inflammatory Mediators with Mitochondrial DNA Variants in Geriatric COVID-19 Patients
Tiziana Casoli, Anna Rita Bonfigli, Mirko Di Rosa, Belinda Giorgetti, Marta Balietti, Robertina Giacconi, Maurizio Cardelli, Francesco Piacenza, Francesca Marchegiani, Fiorella Marcheselli, Rina Recchioni, Roberta Galeazzi, Salvatore Vaiasicca, Adrianapia Maria Lamedica, Alessia Fumagalli, Letizia Ferrara, Fabrizia Lattanzio
| DOI: 10.14336/AD.2023.1123
Supplement

1. Supplementary data.pdf (428KB)

Inhibiting Glutaminase Exerts Opposite Effects on Ovariectomy-Induced and Age-Related Reductions in Murine Bone Mass
Qian Guo, Hongjian Zhao, Zijian Dong, Haozhe Cheng, Meipeng Zhu, Zhong Fang
| DOI: 10.14336/AD.2024.0201
Supplement

1. Supplementary data.pdf (2780KB)

Over-the-Counter Anti-inflammatory Supplements for Adjunctive Rheumatoid Arthritis Therapy: A Comprehensive Narrative Review
Saliba Fares, Mourad Omar, Aoun Laurence, Saif Abu-Baker, Almardini Shaza, Haddadin Fadi, Mina Jonathan, Khattar Georges, Sangaraju Koushik, Bou Sanayeh Elie, Morcos Zeina, Habib Toni, Al Saidi Ibrahim, Slobodnick Anastasia
| DOI: 10.14336/AD.2024.0131
Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions
Xiang-Chun Huang, Yi-Nan Jiang, Hai-Juan Bao, Jie-Lin Wang, Rong-Jin Lin, Jing Yuan, Jing-Yuan Xian, Yang Zhao, Shuo Chen
| DOI: 10.14336/AD.2024.0126
Glutamate Provides Cytoprotective Effect for Astrocytes Against Ischemic Insult and Promotes Astrogliosis
Shao-Hua Yang, Yuanhong Sun, Raymond Berry, Gourav Roy Choudhury, Ali Winters, Kiran Chaudhari, Ran Liu
| DOI: https://dx.doi.org/10.14336/AD.2023.0726
From Insight to Eyesight: Unveiling the Secrets of the Insulin-Like Growth Factor Axis in Retinal Health
Raju V. S. Rajala, Ammaji Rajala
| DOI: 10.14336/AD.2024.0128
Machine Learning-Based Decision-Making in Geriatrics: Aging Phenotype Calculator and Survival Prognosis
Mamchur Aleksandra, Sharashkina Natalia, Erema Veronika, Kashtanova Daria, Ivanov Mikhail, Bruttan Maria, Zelenova Elena, Shelly Eva, Ostapenko Valentina, Dzhumaniiazova Irina, Matkava Lorena, Yudin Vladimir, Akopyan Anna, Strazhesko Irina, Maytesyan Lilit, Tarasova Irina, Beloshevskaya Olga, Keskinov Anton, Tkacheva Olga, Yudin Sergey
| DOI: 10.14336/AD.2024.0120
Supplement

1. Supplementary data.pdf (684KB)

Isthmin-1 Improves Aging-Related Cardiac Dysfunction in Mice through Enhancing Glycolysis and SIRT1 Deacetylase Activity
Min Hu, Xin Zhang, Yi-Peng Gao, Yu-Xin Hu, Teng Teng, Sha-Sha Wang, Qi-Zhu Tang
| DOI: 10.14336/AD.2024.0113
Supplement

1. Supplementary data.pdf (2330KB)

Hypoxic Conditioning: A Potential Perioperative Strategy to Reduce Abdominal Aortic Occlusion-Related Injury in Mouse Proximal and Distal Organs
Changhong Ren, Ning Li, Jun Xu, Yong Yang, Linhui Qin, Linpei Jia, Shuangfeng Huang, Kunlin Jin, Fengyong Liu, Xunming Ji, Sijie Li
| DOI: 10.14336/AD.2024.0121
Judith Campisi (1950-2024) - A Pioneering Geroscientist in Senescence and SASP
Kunlin Jin
| DOI: 10.14336/AD.2024.0123
Choroid Plexus Volume, Amyloid Burden, and Cognition in the Alzheimer’s Disease Continuum
Seong Ho Jeong, Chae Jung Park, Jungho Cha, Sang-Young Kim, Seung-Koo Lee, Yun Joong Kim, Young H. Sohn, Seok Jong Chung, Phil Hyu Lee
| DOI: 10.14336/AD.2024.0118
Optical Coherence Tomography Angiography: Revolutionizing Clinical Diagnostics and Treatment in Central Nervous System Disease
Zeqi Shen, Sheng Zhang, Weitao Yu, Mengmeng Yue, Chaoyang Hong
| DOI: 10.14336/AD.2024.0112
A Systematic Review of Intervention Trials Utilizing Biomarkers Among Informal Caregivers of People with Alzheimer's Disease & Related Dementias
Adam O’Riordan, Michelle A. Chen, Valentina Maza, Nyla Vela, Lydia Wu-Chung, Alexandria Henderson, Olivia L. Carney, Angie S. LeRoy
| DOI: 10.14336/AD.2024.0115
Aging Increases Hypoxia-Induced Endothelial Permeability and Blood-Brain Barrier Dysfunction by Upregulating Arginase-II
Xin Cheng, Duilio M. Potenza, Andrea Brenna, Guillaume Ajalbert, Zhihong Yang, Xiu-Fen Ming
| DOI: 10.14336/AD.2023.1225
Neuroinflammaging: A Tight Line Between Normal Aging and Age-Related Neurodegenerative Disorders
Luca Soraci, Andrea Corsonello, Ersilia Paparazzo, Alberto Montesanto, Francesco Piacenza, Fabiola Olivieri, Maria Elsa Gambuzza, Edlin Villalta Savedra, Silvia Marino, Fabrizia Lattanzio, Leonardo Biscetti
| DOI: 10.14336/AD.2023.1001
DNA Demethylation of Promoter Region Facilitates Atoh-1-Induced Interleukin-19 Expression Activation in Bone Marrow Monocytes of Old Mice
Yanan Chen, Longshuai Lin, Shengzhe Ruan, Jianxin Ye, Zhicheng Dai, Guangzhen Mao, Yongming Xi, Changping Wang, Qinghua Zhao
| DOI: 10.14336/AD.2024.0108
Fighting with Aging: The Secret for Keeping Health and Longevity of Naked Mole Rats
Wenjing Yang, Yifan Hu, Shufang Cui
| DOI: 10.14336/AD.2024.0109
A Potential “Anti-Warburg Effect” in Circulating Tumor Cell-mediated Metastatic Progression?
Zhuofeng Jiang, Jiapeng He, Binyu Zhang, Liping Wang, Chunhao Long, Boxi Zhao, Yufan Yang, Longxiang Du, Weiren Luo, Jianyang Hu, Xin Hong
| DOI: 10.14336/AD.2023.1227
Association of Plasma Markers of Alzheimer’s Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging
Mustapha Bouhrara, Keenan A. Walker, Joseph S. R. Alisch, Zhaoyuan Gong, Caio H. Mazucanti, Alexandria Lewis, Abhay R. Moghekar, Lisa Turek, Victoria Collingham, Nader Shehadeh, Giovanna Fantoni, Mary Kaileh, Christopher M. Bergeron, Jan Bergeron, Susan M. Resnick, Josephine M. Egan
| DOI: 10.14336/AD.2023.1226
Deregulation of the Glymphatic System in Alzheimer’s Disease: Genetic and Non-Genetic Factors
Yan-Hong Hu, Ting Su, Lin Wu, Jun-Fang Wu, Dan Liu, Ling-Qiang Zhu, Mei Yuan
| DOI: 10.14336/AD.2023.1229
Dysregulation of Ion Channels and Transporters and Blood-Brain Barrier Dysfunction in Alzheimer’s Disease and Vascular Dementia
Ruijia Liu, Jenelle M. Collier, Nana-Hawwa Abdul-Rahman, Okan Capuk, Zhongling Zhang, Gulnaz Begum
| DOI: 10.14336/AD.2023.1201
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke
Xiaosong He, Xin Wang, Hui Wang, Tao Wang, Fuhan Yang, Yuchen Chen, Zifei Pei, Yuting Bai, Wen Li, Zheng Wu, Gong Chen
| DOI: 10.14336/AD.2023.1213
Supplement

1. Supplementary data.pdf (1075KB)

Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders
Ashish Kumar, Fred Kim, Dong-Keun Song, Jai Jun Choung
| DOI: 10.14336/AD.2023.1129
Arterial Aging and Cerebrovascular Function: Impact of Aerobic Exercise Training in Older Adults
Tsubasa Tomoto, Rong Zhang
| DOI: 10.14336/AD.2023.1109-1
Current Advances and Future Perspectives on Mesenchymal Stem Cell-Derived Extracellular Vesicles in Alzheimer's Disease
Wenjing Zhang, Russell Uyemura, Kun Zhong, Rui Guo, Li Zhong
| DOI: 10.14336/AD.2023.1206