Editorial
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Vascular Contributions to Healthy Aging and Dementia
Yulin Ge
Perspectives
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Cerebral Small Vessel Disease in Population-Based Research: What are We Looking at - and What not?
Sanne S Mooldijk, M. Arfan Ikram
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N6-Methyladenosine in Vascular Aging and Related Diseases: Clinical Perspectives
Chen Li, Le Liu, Shuang Li, You-Shuo Liu
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Extracellular MicroRNAs as Potential Biomarkers for Frail Kidney Phenotype: Progresses and Precautions
Chia-Ter Chao, Chih-Kang Chiang, Kuan-Yu Hung
Opinion
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Literacy for Frailty among Undergraduate Medical Education: An Under-Recognized Opportunity to Improve Geriatric Care
Chia-Ter Chao
Commentary
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Lactic Acid Bacteria and Aging: Unraveling the Interplay for Healthy Longevity
Rui Liu, Bo Sun
Short Communications
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Senolytic Treatment Improve Small Intestine Regeneration in Aging
Qing-Tian Luo, Yuan-Chun Ye, Wei-Ming Guo, Qing Zhu, Sa-Shuang Wang, Nan Li, Lei Wang, Chun-Sheng Cheng, Gang Fan
Review
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Farnesoid X receptor: From Structure to Function and Its Pharmacology in Liver Fibrosis
Chuan Ding, Zeping Wang, Xinyue Dou, Qiao Yang, Yan Ning, Shi Kao, Xianan Sang, Min Hao, Kuilong Wang, Mengyun Peng, Shuosheng Zhang, Xin Han, Gang Cao
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Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
Qianting Deng, Chongyun Wu, Emily Parker, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
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The Role of Circadian Rhythm in Neurological Diseases: A Translational Perspective
Wanbin Huang, Jiabin Zong, Yu Zhang, Yanjie Zhou, Lily Zhang, Yajuan Wang, Zhengming Shan, Qingfang Xie, Ming Li, Songqing Pan, Zheman Xiao
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Immune Remodeling during Aging and the Clinical Significance of Immunonutrition in Healthy Aging
Lei Dou, Yang Peng, Bin Zhang, Huiyuan Yang, Kai Zheng
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Geriatric Breast Cancer: Staging, Molecular Surrogates, and Treatment. A Review & Meta-analysis
Vasco C Fonseca, Zacharoula Sidiropoulou
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Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia
Ashish Ranjan Sharma, Srijan Chatterjee, Yeon-Hee Lee, Sang-Soo Lee
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Autophagy in Disease Onset and Progression
Hao Wang, Xiushen Li, Qi Zhang, Chengtao Fu, Wenjie Jiang, Jun Xue, Shan Liu, Qingxue Meng, Lisha Ai, Xuejun Zhi, Shoulong Deng, Weizheng Liang
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Arterial Aging and Cerebrovascular Function: Impact of Aerobic Exercise Training in Older Adults
Tsubasa Tomoto, Rong Zhang
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State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease
Elizabeth M Rhea, Manon Leclerc, Hussein N Yassine, Ana W Capuano, Han Tong, Vladislav A Petyuk, Shannon L Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis
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Neuroinflammaging: A Tight Line Between Normal Aging and Age-Related Neurodegenerative Disorders
Luca Soraci, Andrea Corsonello, Ersilia Paparazzo, Alberto Montesanto, Francesco Piacenza, Fabiola Olivieri, Maria Elsa Gambuzza, Edlin Villalta Savedra, Silvia Marino, Fabrizia Lattanzio, Leonardo Biscetti
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Dysregulation of Ion Channels and Transporters and Blood-Brain Barrier Dysfunction in Alzheimer’s Disease and Vascular Dementia
Ruijia Liu, Jenelle M Collier, Nana-Hawwa Abdul-Rahman, Okan Capuk, Zhongling Zhang, Gulnaz Begum
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Effects of Pilates Training on Cardiorespiratory Functions in Medical Conditions - Comprehensive Approach: A Narrative Review
Maria Tarnas, Andrzej Marszałek, Joanna Kufel-Grabowska, Sławomir Marszałek, Dariusz Wieliński, Jacek Zieliński
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The Emerging Role of the Mitochondrial Respiratory Chain in Skeletal Aging
Huaqiang Tao, Pengfei Zhu, Wenyu Xia, Miao Chu, Kai Chen, Qiufei Wang, Ye Gu, Xiaomin Lu, Jiaxiang Bai, Dechun Geng
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Biomarkers of Parkinson’s Disease: From Basic Research to Clinical Practice
Zi-lu Ma, Zhang-li Wang, Fei-yue Zhang, Hong-xun Liu, Li-hong Mao, Lin Yuan
Original Article
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Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals
Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, Rajpaul Attariwala
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Alzheimer Disease Pathology and Neurodegeneration in Midlife Obesity: A Pilot Study
Mahsa Dolatshahi, Paul K Commean, Farzaneh Rahmani, Jingxia Liu, LaKisha Lloyd, Caitlyn Nguyen, Nancy Hantler, Maria Ly, Gary Yu, Joseph E Ippolito, Claude Sirlin, John C Morris, Tammie L.S Benzinger, Cyrus A Raji
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Prospective Longitudinal Perfusion in Probable Alzheimer’s Disease Correlated with Atrophy in Temporal Lobe
Tony D Zhou, Zongpai Zhang, Arvind Balachandrasekaran, Cyrus A Raji, James T Becker, Lewis H Kuller, Yulin Ge, Oscar L Lopez, Weiying Dai, H. Michael Gach
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Association of Arterial Stiffness Index and Brain Structure in the UK Biobank: A 10-Year Retrospective Analysis
Elric Y Allison, Baraa K Al-Khazraji
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Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function
Xiaodan Liu, Giuseppe Barisano, Xingfeng Shao, Kay Jann, John M Ringman, Hanzhang Lu, Konstantinos Arfanakis, Arvind Caprihan, Charles DeCarli, Brian T Gold, Pauline Maillard, Claudia L Satizabal, Elyas Fadaee, Mohamad Habes, Lara Stables, Herpreet Singh, Bruce Fischl, Andre van der Kouwe, Kristin Schwab, Karl G Helmer, Steven M Greenberg, Danny J.J Wang, for the MarkVCID Consortium
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Edge Density Imaging Identifies White Matter Biomarkers of Late-Life Obesity and Cognition
Maxwell Bond Wang, Farzaneh Rahmani, Tammie L. S Benzinger, Cyrus A Raji
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In Vivo Detection of Age-Related Tortuous Cerebral Small Vessels using Ferumoxytol-enhanced 7T MRI
Zhe Sun, Chenyang Li, Thomas W Wisniewski, E. Mark Haacke, Yulin Ge
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PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia
Christina Hoyer-Kimura, Meredith Hay, John P Konhilas, Helena W Morrison, Methawasin Methajit, Joshua Strom, Robin Polt, Victoria Salcedo, Joshua P Fricks, Anjna Kalya, Paulo W Pires
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Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency
Yuxiao Yao, Chenchen Jin, Yilie Liao, Xiang Huang, Ziying Wei, Yahong Zhang, Dongwei Li, Huanxing Su, Weiping Han, Dajiang Qin
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P2Y1R silencing in Astrocytes Protected Neuroinflammation and Cognitive Decline in a Mouse Model of Alzheimer's Disease
Shan Luo, Ami Tamada, Yuichi Saikawa, Yifei Wang, Qing Yu, Tatsuhiro Hisatsune
