Perspective
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Epigenetic Regulation of Regulated Cell Death in Aging-Related Diseases: Clinical Perspectives
Le Liu, Chen Li, Youshuo Liu
Erratum
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Erratum to “Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency”
Feiyan Zhao, Long Yan, Xuehan Zhao, Jiaqi Wu, Ying Fang, Zhimin Xin, Hongmei Wang, Xiaokui Yang
Short Communication
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The HLA-B*57:01 Haplotype, Genetic Key Linking Innate Immunity and Longevity
Myriam Rahmouni, Cristina Giuliani, Daniela Colucci, Nicolás Mendoza-Mejía, Samuel Hiet, Marco Lamanda, Jean-Louis Spadoni, Sigrid Le Clerc, Taoufik Labib, Matilde Manetti, Maxime Tison, Raissa Medina-Santos, Paolo Garagnani, Alexandre How-Kit, Armand Bensussan, Marianne Nygaard, Kaare Christensen, Almut Nebel, Jean-François Deleuze, Jean-François Zagury
Review
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The Impact of Young and/or Exercised Plasma Transfusions in Neurodegenerative Conditions: A Scoping Review
Michael J. Kirton, Emily R. Cox, Ulrik Wisløff, Atefe R. Tari, Lance C. Dalleck, Claire Drummond, Belinda Lange, Ranjay Chakraborty, Kym Williams, Norma Bulamu, Alline Beleigoli, Joyce S. Ramos
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Correlations between Aging, Telomeres, and Natural Compounds
Katarzyna Rakoczy, Laura Wojdyło, Sara Suwała, Karolina Klasen, Jacek Kuźnicki, Marek Ziętek, Julita Kulbacka
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Aging-Related Mechanisms Underlying Carcinogenesis: Therapeutic Opportunities
Ana Guijarro, Giulia Allavena, Livia Pisciotta, Alessio Nencioni, Irene Caffa
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Aβ Deposition in Extracellular Space Disrupts Glial-Neuron Communication and Triggers Alzheimer's Disease
Ying Chen, Ling Ding, Ziqi Gu, Zixi Tian, Tingting Gao, Feiyan Zhou, Shouzi Zhang, Zhiqian Tong
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Hexokinase as a Central Hub in Neurodegeneration: From Metabolic Dysfunction to Therapeutic Innovation
Shiyuan Cai, Yanjun Liu, Bo Liu, Hongli Liao, Ke Li
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Late Onset Rheumatoid Arthritis
Zhao Peng, Wenjing Liu, BinYu Huang, Qian Wang, Xinping Tian, Sean X. Leng, Lin Kang
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Multi-Omics Advances in Major Depressive Disorder for Molecular Insights, Biomarker Discovery, and Therapeutic Development
Abdelbaset Mohamed Elasbali, Mohd Adnan, Ahmed S. Ali, Anas Shamsi, Md. Imtaiyaz Hassan
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Annexin A5 in Ischemic Stroke: Molecular Mechanisms and Translational Therapy Strategies
Zhanwei Zhu, Jiachen He, Qi Liu, Jiaqi Guo, Jingbei Liu, Shuaili Xu, Xi Chen, Di Wu
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Cellular Characterization and Neural Electrophysiology in Cerebral Organoid Models of Neurological Disorders
Quankun Zhou, Ling Ma, Bangming Guo, Peng Li, Ye Song
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Immunosenescence: Driver of Cardiac Aging
Simeng Zhu, Guofang Xia, Yifan Shi, Congfeng Xu
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Emerging Perspectives in Anti-aging Treatments Using Anti-Fibrotic Strategies
Yu Wang, Chenshi Xi, Jiangli Yang, Mingye Wang, Linghui Zeng, Lingxiao Zhang, Chong Gao
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Immunosenescence: Shaping the Hematological Narrative in the Era of Aging
Yajie Wu, Ji Luo, Jiaoya Lin, Shuai Zheng, Yingmiao Wu, Yifei Gao, Jiao Chen, Feifei Che, Ling Zhong
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SIRT1-Mediated Mitochondrial Homeostasis in Cardiac Aging: Molecular Mechanisms and Therapeutic Implications
Sitong Chen, Hanying Xu, Xiaonan Li, Xiaolei Tang, Lan Yang, Jing Lu, Jun Li
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Optimal Evaluation and Treatment of Cardiac Rehabilitation for Patients Following TAVR: A Personalized Program Based on The Five Prescriptions
Xue-Song Han, Gang Wang, Yong Miao, Zhi-Yuan Tian, Yong-Chao Zhang, Zong-Yan Li, Xiao-Jia Sun, Qiang Hu
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Metabolic-Inflammatory Syndrome: Decoding the Metabolic-Immune Axis for Precision Intervention
Simin Li, Yawei Shi, Chongge You
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Advancing Single-Cell Transcriptomic Analysis to Reveal Age-Related Skeletal Muscle Changes: A Systematic Review
Chaoran Liu, Hei Yuet Wong, Ranyang Tao, Baoqi Li, Pui Yan Wong, Chun Ho Tam, Ning Zhang, Ling Qin, Jiankun Xu, Gustavo Duque, Christoph Brochhausen, Wing Hoi Cheung, Ronald Man Yeung Wong
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Potential Risk to Brain Health after Surgical Interventions: Biomarkers to Predict the Occurrence of Cognitive Decline
Julio Rey-Picazo, Jimena Pita, Lucía Peña, Marta Ferraz-Torres, Oscar Martínez-García, Marina Ávila-Villanueva, Gloria Santos-Pérez, David López-Sanz, M. Victoria Moreno-Arribas, Carlos González Perrino, Vicente Muedra, Alfredo Jesús Miñano-Molina, Vicente Hernández-Rabaza, Ulises Gómez-Pinedo, Gonzalo León-Espinosa
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Diversity of Brain Microvascular Endothelial Cell Functions: Physiology, Ischemia/Hypoxia, and Underlying Protection
Mingxuan Cao, Jia Liu, Xunming Ji
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Stroke-Induced Retinal Dysfunction: Mechanisms, Diagnostics, and Future Directions
Ting Wang, Zirun Feng, Jin Yang, Cuiying Liu, Heng Zhao, Sheng Huang
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The Role of Mitochondria-Associated Endoplasmic Reticulum Membranes in Fibrotic Diseases
Fei Wang, Han Wang, Yun chao Zhang, Cao Dan, Yi Ming Qin, Mei Juan Xie, Xiao Yan Lyu
Original Article
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Neuropsychological Diagnostic Tools in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
Nuria Jerez-Garrido, Ana M. Jiménez-García, David Sánchez-Borda, Natalia Arias
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Sphingosine Kinase 2 Inhibition Ameliorates Neuroinflammation in Diet-Induced Obese Mice
Lotte Vanherle, Cecilia Skoug, Lisa Teresa Porschen, Fátima Gimeno-Ferrer, Frank Matthes, João M. N. Duarte, Anja Meissner
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A Signature of Senescence Based on An Analysis of Selected Markers in Primary Vascular Smooth Muscle Cells Cultured In Vitro and Derived from Atherosclerotic Plaque
Agata Głuchowska, Krzysztof Bojakowski, Dorota Janiszewska, Karolina Staniak, Magdalena Dudkowska, Grażyna Mosieniak
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Early-Life Red Light Exposure Extends Lifespan in C. elegans through ROS-AMPK-Driven Mitochondrial Reprogramming
Yao Zhu, Xin Lin, Huiting Wang, Mingming Song, Tao Yang, Yi Jiao, Chang Liu
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Neuronal Necroptosis Drives Neuroinflammation and Cognitive Decline Independent of Neuronal Cell Death
Nidheesh Thadathil, Nicholas A Wolf, Roman Wolf, Carlos Manlio Díaz-García, Sreemathi Logan, Daniel B Owen, Kevin Pham, Willard M Freeman, Arlan Richardson
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Central Obesity Disrupts Brain Network Organization in Aging via Metabolic and Structural Pathways
Marina Fernandez-Alvarez, Karel M. Lopez-Vilaret, Jose L. Cantero, Mercedes Atienza
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Lamotrigine Restores Impairments in Theta Rhythms and LTP as Early Biomarkers of Aβ1-42-Induced Hippocampal Network Dysfunction
Maciej Studzian, Bartosz Bobula, M. Bruce MacIver, Renata Bocian, Anna Kobrzycka, Bartosz Caban, Tomasz Kowalczyk, Jacek Grebowski, Sylwia Michlewska, Maciej M. Jankowski, Krzysztof Tokarski, Paulina Kazmierska-Grebowska
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Cisternostomy Facilitates Clearance of Metabolic Waste from Cerebrospinal Fluid in Patients with Severe Brain Injury
Weiwei He, Shuai Gao, Lulu Du, Tangrui Han, Di Yao, Hao Wu, Qiang Li, Feixiang Li, Woo-ping Ge, Yonghong Wang
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Microglial Replacement Reverses Age-Associated Epigenetic Modifications Despite Accelerating Epigenetic Age
Maria Arbaizar-Rovirosa, Raúl F. Pérez, Alfonso Peñarroya, Mattia Gallizioli, Mario F. Fraga, Anna M. Planas
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Histone H4 Lysine 12 Lactylation Promotes the Senescence of Alveolar Epithelial Type II Cells in Chronic Obstructive Pulmonary Disease by Modulating the CD38-NAD+ Signaling Pathway
Chunxiao Yang, Qi Wang, Yuhan Xiong, Nan Ruan, Jun Yu, Yi Huang, Yu Liu, Cuntai Zhang, Weiwei Yu
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Multimodal In Vivo Imaging Reveals BZBS Capsules Enhance Brain Function and Delay Aging in the Mouse Models
Jiwei Xing, Xiufei Gu, Xin Chen, Guangxing Wang, Huiling Wu, Fengxian Du, Peishan Li, Heng Zhang, Ronghui Li, Yunlong Hou, Qingliang Zhao
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The Ability of Activity and Cognition in Old Mice to Predict Age of Death
Sreemathi Logan, Kavitha Kurup, Michael Chan, Michelle Ranjo-Bishop, Anthony Masingale, Daniel Owen, William E. Sonntag, Arlan Richardson, Archana Unnikrishnan
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Global Burden of Chronic Obstructive Pulmonary Disease and Heart Failure Comorbidity in Older Adults: An Analysis of the Global Burden of Disease Study
Jian Kang, Huiqing Xu, Xiaojing Deng, Yeping Bian, Tianrui Deng, Yunting Xu, Guofeng Ao, Jian Xu, Fei Xu
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IRG1/Itaconate Inhibits Microglial Senescence-Like Transition by Modulating Mitochondrial Dynamics through Rhoa Alkylation in Subarachnoid Hemorrhage
Zeyu Zhang, Yanlin Chen, Weizhen Gao, Fengchen Zhang, Yichao Jin, Jie Li, Jiaqi Wang, Tao Lv, Feng Jia, Xiaohua Zhang
