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Aging and Disease    2017, Vol. 8 Issue (5) : 558-569     DOI: 10.14336/AD.2016.1220
Original Article |
Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
Sheng Peng1,Ting Shen1,Jie Liu1,Brian Tomlinson2,Huimin Sun1,Xiaoli Chen1,Paul Chan3,YaShu Kuang1,Liang Zheng1,Hong Wu4,Xugang Ding4,Dingguang Qian4,Yixin Shen1,Pingjin Gao5,Huimin Fan1,Zhongmin Liu1,*,Yuzhen Zhang1,*
1Key Laboratory of Arrhythmias, Ministry of Education, Research Center for Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China
2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
3Division of Cardiology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
4Gaohang Community Medical Center, Shanghai, 201208, China
5Shanghai Hypertension Institute, Rui Jin Hospital, JiaoTong Univeristy School of Medicine, Shanghai, 200120, China
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Abstract  

We determined the prevalence of hypertension, medication usage and attainment of blood pressure goals in older (≥65 to <80 years and ≥80 years) urban community-dwelling Chinese subjects. Data were obtained in 3950 subjects (mean age 72.0 years, 1745 male) including 609 subjects aged ≥80 years in the Shanghai Elderly Cardiovascular Health Study (SHECHS). Established cardiovascular disease was present in 7.7% of participants. The prevalence of hypertension was 74.8% overall and it was more than 80% in individuals considered to be in moderate and higher cardiovascular disease risk categories. In hypertensive subjects, 67.1% were on treatment and treatment was more frequent in high and very high cardiovascular risk individuals. Attainment of the systolic blood pressure goal <150 mmHg was 62.9% and was greater in the ≥65 to <80 years group than in the ≥80 years group. The most commonly used antihypertensive treatments were calcium channel blockers (54.2%), followed by angiotensin receptor blockers (43.1%). Diuretics were used in 2.6%. Fixed-dose combination antihypertensive tablets were used in some of the ≥65 to <80 years group (12.4%) and more of the ≥80 years group (18.2%) and 70.9% of the ≥65 to <80 years group and 80.2% of the ≥80 years group were on monotherapy. There were high prevalence and high treatment rates of hypertension, but poor attainment of the systolic blood pressure goal of <150 mmHg, especially in the ≥80 years group of community-dwelling Chinese. Considering that more intensive treatment of hypertension in older subjects may be warranted after recent studies, this might be achieved by more frequent use of combinations of effective therapies and diuretics.

Keywords hypertension      prevalence      cardiovascular disease      older Chinese community population     
Corresponding Authors: Zhongmin Liu,Yuzhen Zhang   
Issue Date: 01 October 2017
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Sheng Peng
Ting Shen
Jie Liu
Brian Tomlinson
Huimin Sun
Xiaoli Chen
Paul Chan
YaShu Kuang
Liang Zheng
Hong Wu
Xugang Ding
Dingguang Qian
Yixin Shen
Pingjin Gao
Huimin Fan
Zhongmin Liu
Yuzhen Zhang
Cite this article:   
Sheng Peng,Ting Shen,Jie Liu, et al. Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai[J]. A&D, 2017, 8(5): 558-569.
URL:  
http://www.aginganddisease.org/EN/10.14336/AD.2016.1220     OR     http://www.aginganddisease.org/EN/Y2017/V8/I5/558
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