Please wait a minute...
 Home  About the Journal Editorial Board Aims & Scope Peer Review Policy Subscription Contact us
Early Edition  //  Current Issue  //  Open Special Issues  //  Archives  //  Most Read  //  Most Downloaded  //  Most Cited
Aging and disease    2018, Vol. 9 Issue (2) : 296-308     DOI: 10.14336/AD.2017.0309
Review |
Effects of Elastic Therapeutic Taping on Knee Osteoarthritis: A Systematic Review and Meta-analysis
Li Xin1, Zhou Xuan1, Liu Howe3, Chen Nan1, Liang Juping1, Yang Xiaoyan1, Zhao Guoyun1, Song Yanping2, Du Qing1,2,*
1Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
2Chongming Branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
3University of North Texas Health Science Center, Texas 76107, USA
Download: PDF(2401 KB)   HTML
Export: BibTeX | EndNote | Reference Manager | ProCite | RefWorks    

Elastic therapeutic taping (ET) has been widely used for a series of musculoskeletal diseases in recent years. However, there remains clinical uncertainty over its efficiency for knee osteoarthritis (knee OA) management. To assess the effects of ET on patients with knee OA, we investigated outcomes including self-reported pain, knee flexibility, knee-related health status, adverse events, muscle strength, and proprioceptive sensibility. Ten databases including PubMed, EMBASE, Cochrane Library, CINAHL, Web of Science, PEDro, Research Gate, CNKI, CBM, and Wanfang were systematically searched. Eleven randomized controlled trials (RCTs) with 168 participants with knee OA provided data for the meta-analysis. Statistical significance was reported in four from five outcomes, such as self-related pain (during activity, MD -0.85, 95% CI, -1.55 to -0.14; P =0.02), knee flexibility (MD 7.59, 95% CI, 0.61 to 14.57; P =0.03), knee-related health status (WOMAC scale, MD -4.10, 95% CI, -7.75 to -0.45; P =0.03), and proprioceptive sensibility (MD -4.69, 95% CI, -7.75 to -1.63; P =0.003), while no significant enhancement was reported regarding knee muscle strength (MD 1.25, 95% CI, -0.03 to 2.53; P =0.06). Adverse events were not reported in any of the included trials. The overall quality of evidence was from moderate to very low. In conclusion, there is underpowered evidence to suggest that ET is effective in the treatment of knee OA. Large, well-designed RCTs with better designs are needed.

Keywords Kinesiotape      Knee osteoarthritis      Systematic review      Meta-analysis     
Corresponding Authors: Du Qing   
About author:

These authors contributed equally to this work.

Issue Date: 01 April 2018
E-mail this article
E-mail Alert
Articles by authors
Li Xin
Zhou Xuan
Liu Howe
Chen Nan
Liang Juping
Yang Xiaoyan
Zhao Guoyun
Song Yanping
Du Qing
Cite this article:   
Li Xin,Zhou Xuan,Liu Howe, et al. Effects of Elastic Therapeutic Taping on Knee Osteoarthritis: A Systematic Review and Meta-analysis[J]. Aging and disease, 2018, 9(2): 296-308.
URL:     OR
Figure 1.  Review flow diagram
Figure 2.  Self-reported pain (evaluated by VAS or NPRS) for ET compared with other forms of treatment. (A) pain at rest; (B) pain at night; (C) pain during activity.
Patient Characteristics,
Sample Size
InterventionDuration of
trial period
Outcomes/Time point/Effectiveness
Yu (2012)
Source: 40 patients with
knee OA (G1=20,G2=20) Mean age (SD): G1=51.12y (4.29), G2=50.97y(5.01)
G1: Therapeutic KT with less than 10% tension
G1: 24-hour each time, daily taping for 7 days
G2: 20 min each time, daily treatment for 7 days
1. Pain intensity (VAS) / (Baseline, 3days*, 7days);
2. Functional disability (LI) / (Baseline, 3days*, 7days), (WOMAC) / (Baseline, 3days, 7days)
[24] Anandkumar (2014)Source: 40 outpatients
(G1=20, G2=20). Mean age (SD): G1=55.7y (5.8), G2=55.9y (5.0)
G1: Therapeutic KT with 50%-75% tension
G2: Sham taping
Taping for 30 min1. Peak isokinetic quadriceps torque (concentric and eccentric at angular velocities of 90° per second and 120° per second) / (Baseline, 30 min*);
2. Physical function (SSCT) / (Baseline, 30 min*); 3. Pain intensity (VAS) / (Baseline, 30 min*)
[25] Cho (2015)Source: 46 volunteer subjects with knee OA (G1=23, G2=23).
Mean age(SD):G1=58.2y(4.5), G2=57.5y (4.4)
G1: Therapeutic KT with 15%-25% tension
G2: Sham taping
Taping for 60 min1. Pain-free ROM of the knee joint (Active ROM) / (Baseline, 60 min*)
2. Pain intensity at rest (VAS), (PPT in quadriceps), (PPT in tibialis anterior) / (Baseline, 60 min); 3. Pain intensity during walking (VAS), (PPT in quadriceps), (PPT in tibialis anterior) / (Baseline, 60 min*); 4. Proprioceptive acuity (AJPR at 15, 30, and 45 degrees) / (Baseline, 60 min*)
[26] Kocyigit (2015)Source: 41 outpatients with knee OA (G1=21, G2=20).
Mean age(SD):G1=52y(7.5), G2=52y (10)
G1: Therapeutic KT with 25% tension
G2: Sham taping
Taping was repeated every 4 days, 3 times in total1. Functional disability (LI) / (Baseline, 12 days);
2. Quality of life (NHP pain score, NHP physical activity score, NHP sleep score, NHP social isolation score, NHP total score) / (Baseline, 12 days); 3. Quality of life (NHP energy score) / (Baseline, 12 days*);4. Pain intensity with activity and at night (VAS) / (Baseline, 12 days);
[27] Wageck (2016)Source: 76 outpatients with knee OA (G1=38, G2=38).
Mean age(SD):G1=69.6y(6.9), G2=68.6y (6.3)
G1: A multi-layer KT application
G2: Sham taping
Taping for 4 days, follow
-up for extra 15 days
1. Muscle strength (Knee extensor and flexor isokinetic concentric strength)/ (Baseline, 4 days, 19 days);
2. Pain intensity (PPT) / (Baseline, 4 days, 19 days); 3. Functional disability (WOMAC) / (Baseline, 4 days, 19 days); 4. Lower limb volume/ (Baseline, 4 days, 19 days); 5. Perimeter of the limb/ (Baseline, 4 days, 19 days); 6. Physical function (LKSS) / (Baseline, 4 days, 19 days)
Lee (2016)
Source: 30 elderly patients with knee OA (G1=15, G2=15).
Mean age(SD):G1=72.0y(4.0), G2=73.1y (5.8)
G1: KT
3 times/week for 4 weeks.1. Pain intensity (VAS) / (Baseline, 4 weeks*);
2. Functional disability (K-WOMAC) / (Baseline, 4 weeks*); 3. Pain-free ROM of the knee joint (Passive ROM) / (Baseline, 4 weeks*);
[29] Dhanakotti (2016)Source: 30 patients with
knee OA(G1=15, G2=15). Mean age(SD):G1=51.73y(5.10), G2=51.26y (4.86)
G1: KT with 40% stretch of its maximal length+ CPT
3 times/week for 3 weeks1. Pain intensity (NPRS) / (Baseline, 3 weeks*);
2. Muscle strength (Maximum isometric force of quadriceps) / (Baseline, 3 weeks*); 3. Functional disability (m.WOMAC) / (Baseline, 3 weeks*);
Kaya (2016)
Source: 39 outpatients with
knee OA (G1=20, G2=19). Mean age(SD): G1=52y (7.5), G2=52y (10)
G1: Therapeutic KT with 25% tension
G2: Placebo KT
12 to 16 days in total1. Pain intensity (VAS during activity), Functional disability (ALF-walking) / (Baseline, after the initial KT, after the third KT*, 1 month follow-up*),
2. Pain intensity (VAS at night), Pain-free ROM of the knee flexion (Active ROM) / (Baseline, after the initial KT, after the third KT, 1 month follow-up*), 3. Pain intensity (VAS at rest), Functional disability (WOMAC), Pain-free ROM of the knee and hip joints (Active ROM except knee flexion), Muscle strength (Maximum isometric force of iliopsoas, gluteus medius, quadriceps, and hamstring muscles)/ (Baseline, after the initial KT, after the third KT, 1 month follow-up)
Atya (2015)
Source: 60 outpatients with knee OA (G1=20, G2=20, G3=20)
Mean age (SD): G1=38.7y (7.7), G2=38.6y (7.5), G3=37.6y(5.6)
TEP/ST: 3 times /week for 8 weeks
KT: wear tape for 2 days and return for review after 24 hours removing tape
1. Pain intensity (VNS) / (Baseline, 8 weeks*);
2. Proprioceptive acuity (AJPR) / (Baseline, 8 weeks); 3. Physical function (AIFAS) / (Baseline, 8 weeks)
Sedhom (2016)
Source: 40 females with knee OA from outpatient (G1=20, G2=20)
Mean age(SD): G1=48.7y (5.82), G2=49.25y (5.82)
G2: HP+SEP+Aescin and Diethylamine Salicylate gel PH with PUT
3 times /week for 4 weeks1. Pain intensity (VAS) / (Baseline, 4 weeks)
2. Proprioceptive accuracy (AJPR) / (Baseline, 4 weeks) 3. Pain-free ROM of the knee joint (Active ROM) / (Baseline, 8 weeks)
[33] Malgaonkar (2014)Source: 40 subjects with knee OA (G1=20, G=20).
Mean age(SD): G1=53.5y (2.21), G2=52.95y (2.25)
G1: Therapeutic KT with 25% tension
3 times/week for 2 weeks1. Pain intensity (VAS) / (Baseline, 2 weeks)
2. Functional disability (WOMAC) / (Baseline, 2 weeks)
Table 1  Characteristics of studies reporting the effectiveness of ET in knee OA and controls.
Figure 3.  The funnel plot regarding self-reported pain during activity.
Author, YearRandom sequence generationAllocation
Blinding of Participants and personnelBlinding of outcome assessmentsIncomplete outcome dataSelective reportingOther bias
[23] Yu, 2012LowUnclearUnclearUnclearLowLowLow
Anandkumar, 2014
[25] Cho, 2015LowLowLowLowHighLowHigh
[26] Kocyigit, 2015LowLowLowLowLowLowLow
[27] Wageck, 2016LowLowLowLowHighLowHigh
[28] Lee, 2016HighUnclearUnclearUnclearLowLowHigh
[29] Dhanakotti, 2016LowLowHighLowLowLowLow
[30] Kaya, 2016LowLowLowLowHighLowHigh
[31] Atya, 2015LowLowLowLowUnclearLowUnclear
[32] Sedhom, 2016LowUnclearUnclearUnclearLowLowHigh
[33] Malgaonkar, 2014LowLowUnclearUnclearLowLowUnclear
Table 2  The Cochrane Collaboration’s tool of assessing risk of bias for methodological assessment.
Figure 4.  Knee flexibility (evaluated by knee ROM) for ET compared with other forms of treatment.
Figure 5.  Knee-related health status (evaluated by WOMAC or LI scales) for ET compared with other forms of treatment. (A) WOMAC; (B) LI.
Figure 6.  Knee muscle strength (evaluated by maximum isometric force of quadriceps) for ET compared with other forms of treatment.
Figure 7.  Proprioceptive Sensibility for ET compared with other forms of treatment.
[1] Johnson VL, Hunter DJ (2014). The epidemiology of osteoarthritis. Best Pract Res Clin Rheumatol, 28(1): 5-15.
[2] Litwic A, Edwards MH, Dennison EM, Cooper C (2013). Epidemiology and burden of osteoarthritis. Br Med Bull, 105: 185-99.
[3] Fahlman L, Sangeorzan E, Chheda N (2013). Older subjects without radiographic knee osteoarthritis: weight, height, and body mass index. Aging Dis, 4(4): 201-9.
[4] Felson DT, Niu J, McClennan C, Sack B, Aliabadi P, Hunter DJ, et al (2007). Knee buckling: prevalence, risk factors, and associated limitations in function. Ann Intern Med, 147(8): 534-40.
[5] Skou ST, Wrigley TV, Metcalf BR, Hinman RS, Bennell KL (2014). Association of knee confidence with pain, knee instability, muscle strength, and dynamic varus-valgus joint motion in knee osteoarthritis. Arthrit Care Res, 66(5): 695-701.
[6] Knoop J, van der LM, van der EM, Thorstensson CA, Gerritsen M, Voorneman RE, et al (2012). Association of lower muscle strength with self-reported knee instability in osteoarthritis of the knee: results from the Amsterdam Osteoarthritis cohort. Arthrit Care Res, 64(1): 38-45.
[7] Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, et al (2008). OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage, 16(2): 137-62.
[8] Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, et al (2010). OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage, 18(4): 476-99.
[9] Ahn IK, Kim YL, Bae Y-H, Lee SM (2015). Immediate effects of kinesiology taping of quadriceps on motor performance after muscle fatigued induction. Evid Based Complement Alternat Med, 2015: 1-7.
[10] Kase K WJ, Kase T (2003), editors. Clinical therapeutic applications of the kinesio taping method 3rd edition. Tokyo: Ken Clin Co., Ltd.
[11] Kamper SJ, Henschke N (2013). Kinesio taping for sports injuries. Br J Sports Med, 47(17): 1128-9.
[12] Williams S, Whatman C, Hume PA, Sheerin K (2012). Kinesio taping in treatment and prevention of sports injuries: a meta-analysis of the evidence for its effectiveness. Sports Med, 42(2): 153-64.
[13] Kalron A, Bar-Sela S (2013). A systematic review of the effectiveness of Kinesio Taping--fact or fashion? Eur J Phys Rehabil Med, 49(5): 699-709.
[14] Montalvo AM, Cara EL, Myer GD (2014). Effect of kinesiology taping on pain in individuals with musculoskeletal injuries: systematic review and meta-analysis. Phys Sportsmed, 42(2): 48-57.
[15] Lim EC, Tay MG (2015). Kinesio taping in musculoskeletal pain and disability that lasts for more than 4 weeks: is it time to peel off the tape and throw it out with the sweat? A systematic review with meta-analysis focused on pain and also methods of tape application. Br J Sports Med, 49(24): 1558-66.
[16] de Oliveira MM, Aragao FA, Vaz MA (2013). Neuromuscular electrical stimulation for muscle strengthening in elderly with knee osteoarthritis- a systematic review. Complement Ther Clin Pract, 19(1): 27-31.
[17] Brown GA (2013). AAOS clinical practice guideline: treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition. J Am Acad Orthop Surg, 21(9): 577-9.
[18] Moher D, Liberati A, Tetzlaff J, Altman DG (2010). Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg, 8(5): 336-41.
[19] Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, et al (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ, 343: d5928.
[20] Hopp L (2015). Risk of bias reporting in Cochrane systematic reviews. Int J Nurs Pract, 21(5): 683-6.
[21] Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003). Measuring inconsistency in meta-analyses. BMJ, 327(7414): 557-60.
[22] Balshem H, Helfand M, Schünemann HJ (2011). GRADE guidelines: 3. Rating the quality of evidence (confidence in the estimates of effect). Z Evid Fortbild Qual Gesundhwes, J Clin Epidemiol. 64(4): 401-6
[23] Yu B, Feng N, Qi Q, He JS, Li YH, Zhai Q, et al (2012). Short-term effects of kinesio taping on knee osteoarthritis relief. Chin J Rehabil Med, 27: 56-8.
[24] Anandkumar S, Sudarshan S, Nagpal P (2014). Efficacy of kinesio taping on isokinetic quadriceps torque in knee osteoarthritis: a double blinded randomized controlled study. Physiother Theor Pr, 30(6): 375-83.
[25] Cho HY, Kim EH, Kim J, Yoon YW (2015). Kinesio taping improves pain, range of motion, and proprioception in older patients with knee osteoarthritis: a randomized controlled trial. Am J Phys Med Rehabil, 94(3): 192-200.
[26] Kocyigit F, Turkmen MB, Acar M, Guldane N, Kose T, Kuyucu E, et al (2015). Kinesio taping or sham taping in knee osteoarthritis? A randomized, double-blind, sham-controlled trial. Complement Ther Clin Pract, 21(4): 262.
[27] Wageck B, Nunes GS, Bohlen NB, Santos GM, de Noronha M (2016). Kinesio taping does not improve the symptoms or function of older people with knee osteoarthritis: a randomised trial. J Physiother, 62(3): 153-8.
[28] Lee K, Yi CW, Lee S (2016). The effects of kinesiology taping therapy on degenerative knee arthritis patients’ pain, function, and joint range of motion. J Phys Ther Sci, 28(1): 63-6.
[29] Dhanakotti S, Samuel RK, Thakar M, Doshi S, Vadsola K (2016). Effects of additional kinesiotaping over the conventional physiotherapy exercise on pain, quadriceps strength and knee functional disability in knee osteoarthritis participants: a randomized controlled study. IJHSR, 6(1): 221-9.
[30] Kaya ME, Mustafaoglu R, Birinci T, Razak OA (2016). Does Kinesio taping of the knee improve pain and functionality in patients with knee osteoarthritis?: a randomized controlled clinical trial. Am J Phys Med Rehabil, 96: 25-33.
[31] Atya ARI, Azza M (2015). Kinesio taping versus sensorymotor training for patients with knee osteoarthritis. IJTRR, 4(3): 9-14.
[32] Sedhom MG (2016). Efficacy of kinesio-taping versus phonophoresis on knee osteoarthritis: an experimental study. Int J Physiother, 3(4): 494-99.
[33] Malgaonkar PP, Sai KN, Vinod BK, Rizvi SR (2014). Short term effect of Mulligan’s mobilization versus kinesio taping on knee pain and disability for osteoarthritis of knee. International J Physiother, 1(4): 233-240.
[34] Larroy C (2002). Comparing visual-analog and numeric scales for assessing menstrual pain. Behav Med, 27(4): 179-181.
[35] Nelson NL (2016). Kinesio taping for chronic low back pain: A systematic review. J Bodyw Mov Ther, 20(3): 672-81.
[36] Mostafavifar M, Wertz J, Borchers J (2012). A systematic review of the effectiveness of kinesio taping for musculoskeletal injury. Phys Sportsmed, 40(4): 33-40.
[37] Furlan AD, Malmivaara A, Chou R, Maher CG, Deyo RA, Schoene M, et al (2015). 2015 Updated Method Guideline for Systematic Reviews in the Cochrane Back and Neck Group. Spine (Phila Pa 1976), 40(21): 1660-73.
[38] Costa LO, Lin CW, Grossi DB, Mancini MC, Swisher AK, Cook C, et al (2013). Clinical trial registration in physiotherapy journals: recommendations from the international society of physiotherapy journal editors. Physiother Can, 65(2): 109-15.
[39] Bellamy N, Carette S, Ford PM, Kean WF, le Riche NG, Lussier A, et al (1992). Osteoarthritis antirheumatic drug trials. III. Setting the delta for clinical trials: results of a consensus development (Delphi) exercise. J Rheumatol, 19: 451-7.
[40] Angst F, Aeschlimann A, Stucki G (2001). Smallest detectable and minimal clinically important differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower extremities. Arthritis Rheum. Aug, 45(4): 384-91.
[1] Jiang Xue,Jiarui Li,Jiaming Liang,Shulin Chen. The Prevalence of Mild Cognitive Impairment in China: A Systematic Review[J]. A&D, 2018, 9(4): 706-715.
[2] Jing-Zhan Zhang,Xiang Xie,Yi-Tong Ma,Ying-Ying Zheng,Yi-Ning Yang,Xiao-Mei Li,Zhen-Yan Fu,Chuan-Fang Dai,Ming-Ming Zhang,Guo-Ting Yin,Fen Liu,Bang-Dang Chen,Min-Tao Gai. Association between Apolipoprotein C-III Gene Polymorphisms and Coronary Heart Disease: A Meta-analysis[J]. A&D, 2016, 7(1): 36-44.
[3] Judit Takacs,Mark G. Carpenter,S. Jayne Garland,Michael A. Hunt. The Role of Neuromuscular Changes in Aging and Knee Osteoarthritis on Dynamic Postural Control[J]. Aging and Disease, 2013, 4(2): 84-99.
Full text



Copyright © 2014 Aging and Disease, All Rights Reserved.
Address: Aging and Disease Editorial Office 3400 Camp Bowie Boulevard Fort Worth, TX76106 USA
Fax: (817) 735-0408 E-mail:
Powered by Beijing Magtech Co. Ltd