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Aging and disease    2020, Vol. 11 Issue (3) : 465-469     DOI: 10.14336/AD.2020.0422
Editorial |
Adipose Stem Cells (ASCs) and Stromal Vascular Fraction (SVF) as a Potential Therapy in Combating (COVID-19)-Disease
Pietro Gentile1,*, Aris Sterodimas2
1Department of Surgical Science, University of Rome Tor Vergata, Rome, Italy
2Department of Plastic and Reconstructive Surgery, Metropolitan General Hospital, Athens, Greece
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Abstract  

A recent and interesting study reported improved respiratory activity after intravenous administration of mesenchymal stem cells (MSCs) into patients affected by coronavirus disease 2019 (COVID-19). These outcomes displayed that intravenous infiltration of MSCs is a safe and efficacy treatment for COVID-19 pneumonia, a severe acute respiratory illness caused by the coronavirus 2 (SARS-CoV-2). Only 7 patients were treated, but with extraordinary results, opening a new strategy in COVID-19 therapy. Currently, no specific therapies against SARS-CoV-2 are available. The MSCs therapy outcomes reported, are striking, as these cells inhibit the over-activation of the immune system, promoting endogenous repair, by improving the lung microenvironment after the SARS-CoV-2 infection. The MSCs could represent an effective, autologous and safe therapy, and therefore, sharing these published results, here is reported the potential use possibilities in COVID-19 of the most common MSCs represented by Adipose Stem Cells (ASCs).

Keywords coronavirus      mesenchymal stem cells      Covid-19      adipose derived stem cells      Adipocyte secreted exosomal microRNA     
Corresponding Authors: Gentile Pietro   
Just Accepted Date: 22 April 2020   Issue Date: 13 May 2020
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Gentile Pietro,Sterodimas Aris. Adipose Stem Cells (ASCs) and Stromal Vascular Fraction (SVF) as a Potential Therapy in Combating (COVID-19)-Disease[J]. Aging and disease, 2020, 11(3): 465-469.
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