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Aging and disease    2020, Vol. 11 Issue (6) : 1352-1362     DOI: 10.14336/AD.2020.0901
Commentary Article |
A Potential Role for Photobiomodulation Therapy in Disease Treatment and Prevention in the Era of COVID-19
Ann Liebert1,2,3,*, Brian Bicknell4,3, Wayne Markman5,3, Hosen Kiat6,7,8
1Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
2Research and Governance, Adventist Hospital Group, Wahroonga, Australia.
3SYMBYX Pty Ltd, Artarmon, Australia.
4Faculty of Health Science, Australian Catholic University, North Sydney, Australia.
5School of Business, University of Technology, Sydney, Australia.
6Cardiac Health Institute, Sydney, Australia.
7Faculty of Medicine, University of NSW, Kensington, Australia.
8Faculty of Medicine, health and Human Sciences, Macquarie University, Macquarie Park, Australia
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COVID-19 is an evolving pandemic that has far reaching global effects, with a combination of factors that makes the virus difficult to contain. The symptoms of infection can be devastating or at the least very debilitating for vulnerable individuals. It is clear that the elderly are at most risk of the adverse impacts of the virus, including hospitalization and death. Others at risk are those with comorbidities such as cardiovascular disease and metabolic conditions and those with a hyper-excitable immune response. Treatment options for those with acute responses to the virus are limited and there is an urgent need for potential strategies that can mitigate these severe effects. One potential avenue for treatment that has not been explored is the microbiome gut/lung axis. In addition to those severely affected by their acute reaction to the virus, there is also a need for treatment options for those that are slow to recover from the effects of the infection and also those who have been adversely affected by the measures put in place to arrest the spread of the virus. One potential treatment option is photobiomodulation (PBM) therapy. PBM has been shown over many years to be a safe, effective, non-invasive and easily deployed adjunctive treatment option for inflammatory conditions, pain, tissue healing and cellular energy. We have also recently demonstrated the effectiveness of PBM to alter the gut microbiome. PBM therapy is worthy of consideration as a potential treatment for those most vulnerable to COVID-19, such as the elderly and those with comorbidities. The treatment may potentially be advantageous for those infected with the virus, those who have a slow recovery from the effects of the virus and those who have been denied their normal exercise/rehabilitation programs due to the isolation restrictions that have been imposed to control the COVID-19 pandemic.

Keywords COVID-19      photobiomodulation      immunomodulation      mitochondrial dysfunction      microbiome     
Corresponding Authors: Liebert Ann   
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These authors contributed equally to this work.

Just Accepted Date: 08 September 2020   Issue Date: 19 November 2020
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Liebert Ann
Bicknell Brian
Markman Wayne
Kiat Hosen
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Liebert Ann,Bicknell Brian,Markman Wayne, et al. A Potential Role for Photobiomodulation Therapy in Disease Treatment and Prevention in the Era of COVID-19[J]. Aging and disease, 2020, 11(6): 1352-1362.
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Figure 1.  Conditions that have been shown to be successfully treated using photobiomodulation therapy.
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