Alzheimer’s disease (AD) has been largely characterized by severe deterioration of cognitive functioning. Only recently has more attention been shifted to identifying the preserved capacity and functioning of AD patients. By reviewing the AD literature, we observe that despite the various cognitive impairment and deficits, early Alzheimer’s patients perform certain types of automatic emotion regulation and display a positivity effect in emotion recognition and emotional memory.Moreover, we argue that, like their healthy aged peers, the optimization of such preserved emotion-based capacities helps early AD patients increase positive emotions, which may counteract the negative effects of the disease, thus maintaining their socio-emotional functioning. Finally, we discuss the emotion-based capacities strategies that AD patients may use to facilitate their adjustment to a life with Alzheimer’s.
Zhang Fan,Ho YuanWan,Fung* Helene H.. Learning from Normal Aging:Preserved Emotional Functioning Facilitates Adaptation among Early Alzheimer’s Disease Patients[J]. Aging and disease,
2015, 6(3): 208-215.
Harris PB (2008). Another wrinkle in the debate about successful aging: the undervalued concept of resilience and the lived experience of dementia. Int J Aging Hum Dev, 67: 43-61.
Hildon Z, Montgomery S M, Blane D, Wiggins RD, Netuveli G (2010). Examining resilience of quality of life in the face of health-related and psychosocial adversity at older ages: What is “right” about the way we age?. Gerontologist, 50: 36-47.
Ong AD, Bergeman CS, Bisconti, TL (2006). Psychological resilience, positive emotions, and successful adaptation to stress in later life. J Pers Soc Psychol, 91: 730-749.
Ong, AD (2010). Pathways linking positive emotion and health in later life. Curr Dir Psychol Sci. 19: 358-362.
Ong AD, Bergeman, CS, Boker SM (2009). Resilience comes of Age: Deﬁning features in later adulthood. J Pers, 77: 1777-1804.
Uchino BN, Berg CA, Smith TW, Pearce G, Skinner M (2006). Age-related differences in ambulatory blood pressure during daily stress: Evidence for greater blood pressure reactivity with age. Psychol Aging, 21: 231-239.
Isaacowitz DM, Wadlinger HA, Goren D, Wilson HR. (2006). Is there an age-related positivity effect in visual attention? A comparison of two methodologies. Emotion 6: 511-516.
Mather M, Carstensen LL. (2003). Aging and attentional biases for emotional faces. Psychol.Sci. 14:409-415.
Carstensen LL, Pasupathi M, Mayr U, Nesselroade JR.2000. Emotional experience in everyday life across the adult life span. J.Personal. Soc. Psychol. 79:644-655.
Diener E., Suh ME. (1997). Subjective well-being and age: an international analysis. In: Schaie, KW, Lawton MP, editors. Annual Review of Gerontology and Geriatrics. New York: Springer, Vol.17, 304-323
Mroczek DK, Kolarz CM.1998. The effect of age on positive and negative affect: a developmental perspective on happiness. J.Pers. Soc. Psychol. 75:1333-1349.
Hay EL, Diehl M (2012). Emotion complexity and emotion regulation across adulthood. Eur J Ageing. 8:157-168.
Diener E, Sandvik E, Larsen RJ.1985. Age and sex effects for emotional intensity. Dev Psychol. 21:542-546
Lawton MP, Kleban MH, Rajagopal D, Dean J.1992. Dimensions of affective experience in three age groups. Psychol. Aging 7: 171-184.
Carver CS, Scheier MF (1993). Vigilant and avoidant coping in two patient samples. In: Krohne, HW, editor. Attention and avoidance: Strategies in coping with aversiveness. Kirkland, WA: Hogrefe & Huber Publishers, 295-319.
Kubzansky LD, Sparrow D, Vokonas P, Kawachi I (2001). Is the glass half empty or half full? A prospective study of optimism and coronary heart disease in the normative aging study. Psychosom Med, 63: 910-916.
Lefcourt, HM(2001). The humor solution. In: Snyder CR, editor. Coping with stress: Effective people and processes. London: Oxford University Press, 8-92.
Fredrickson BL, Mancuso RA, Branigan C, Tugade M M (2000). The Undoing Effect of Positive Emotion. Motiv Emot, 24: 237-258.
Wichers M, Jacobs N, Derom C, Thiery E, Os JV (2007). Depression: Too Much Negative Affect or Too Little Positive Affect? Twin Res Hum Genet, 10(S): 19-20.
Southwick SM, Charney, DS (2012). The Science of Resilience: Implications for the Prevention and Treatment of Depression. Science, 338: 79-82.
Fredrickson BL, Tugade MM, Waugh CE, Larkin GR (2003). What good are positive emotions in crisis? A prospective study of resilience and emotions following the terrorist attacks on the United States on September 11th, 2001. J Pers Soc Psychol, 84: 365-376.
Fredrickson, BL (2001). The Role of Positive Emotions in Positive Psychology: The Broaden-and-Build Theory of Positive Emotions. Am Psychol, 56: 218-226.
Tice DM, Baumeister RF, Shmueli D, Muraven, M (2007). Restoring the self: Positive aVect helps improve self-regulation following ego depletion. J Exp Soc Psychol. 43: 379-384.
Tugade MM (2011). Positive emotion and coping: Examining dual-process models of resilience. In: Folkman S, editor. Oxford Handbook of stress, health, and coping. New York: Oxford University Press, 186-199.
Bonanno GA (2004). Loss, trauma, and human resilience: Have we underestimated the human capacity to thrive after extremely aversive events? Am Psychol, 59: 20-28.
Carstensen LL (2006). The influence of a sense of time on human development. Science, 312:1913-1915.
Shallcross AJ, Ford BQ, Floerke VA, Mauss IB (2012). Getting better with age: the relationship between age, acceptance, and negative affect. J Pers Soc Psychol, 104: 734-749
Lamond AJ, Depp CA, Allison M, Langer R, Reichstadt J, Moore DJ,et al (2009). Measurement and predictors of resilience among community-dwelling older women. J of Psychiatr Res, 43: 148-154.
Kessler EM, Staudinger UM (2009). Affective Experience in Adulthood and Old Age: The Role of Affective Arousal and Perceived Affect Regulation. Psychol Aging: 24: 349-362.
Windle G (2011). What is Resilience? A Review and Concept Analysis. Rev Clin Gerontol, 21: 152-169.
Davis MC, Zautra AJ, Johnson LM, Murray KE, Okvat HA (2007). Psychosocial stress, emotion regulation, and resilience among older adults. In: Aldwin C, Park C, Spiro A, Abeles R, editors. Handbook of health psychology and aging. New York: Guilford, 250-266.
Wiles JL, Wild K, Kerse N, Allen RE (2012). Resilience from the point of view of older people: ‘There’s still life beyond a funny knee’. Soc Sci Med, 74: 416-424.
Nakashima M, Canda, ER. (2005). Positive dying and resiliency in later life: a qualitative study. J Aging Stud, 19: 109-125.
Takeda M, Hashimoto R, Kudo T, Okochi M, Tagami S, Morihara T (2010). Laughter and humor as complementary and alternative medicines for dementia patients. BMC Complement Altern Med, 10: 28.
Goodkind MS, Gyurak A, McCathy M, Miller BL, Levenson RW (2010). Emotion Regulation Deficits in Frontotemporal Lobar Degeneration and Alzheimer’s Disease. Psychol Aging, 25: 30-37.
Rosen HJ, Hartikainen, KM, Jagust W, Kramer JH, Reed, BR, Cummings JLet al (2002). Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD. Neurology, 58: 1608-1615.
Cohen D, Eisdorfer C. The Loss of self: A family resource for the care of Alzheimer’s disease and related disorders. New York: Norton; 1986.
Harris PB, Durkin D (2002). Building resilience through coping and adapting. In: Harris PB, editor. The person with Alzheimer's Disease, Baltimore: The Johns Hopkins University Press, 165-184.
Thompson R, Gross JJ (2007). Emotion regulation. In: Gross JJ, editor. Handbook of Emotion Regulation, New York: Guilford Press; 3-24.
Royall DR, Lauterbach EC, Cummings JL, Reeve A, Rummans TA, Kaufer DI,et al (2002). Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association. J Neuropsychiatry Clin Neurosci, 14: 377-405.
Gyurak A, Goodkind MS, Kramer JH, Miller B L, Levenson RW (2012). Executive functions and the down-regulation and up-regulation of emotion. Cogn Emot, 26: 103-118.
Schmeichel BJ, Volokhov RN, Demaree HA (2008). Working-memory capacity and the self-regulation of emotional expression and experience. J Pers Soc Psychol, 95: 1526-1540.
Henry J D, Rendell PG, Scicluna A, Jackson MM, Phillips LH (2009). Emotion Experience, Expression, and Regulation in Alzheimer’s Disease. Psychol Aging. 24: 252-257.
McLellan T, Johnston L, Dalrymple-Alford J, Porter R (2008). The recognition of facial expressions of emotion in Alzheimer’s disease: A review of ﬁndings. Acta Neuropsychiatr, 20: 236-250.
Kensigner EA, Anderson A, Growdon JH, Corkin S (2004). Effects of Alzheimer disease on memory for verbal emotional information. Neuropsychologia, 42: 791-800.
Burton KW, Kaszniak AW (2006). Emotional experience and facial expression in Alzheimer’s disease. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 13: 636-651.
Nash S, Henry JD, McDonald S, Martin I, Brodaty H, Peek-O’Leary MA (2007). Cognitive disinhibition and siocioemotional functioning in Alzheimer’s Disease. J Int Neuropsychol Soc, 13: 1060-1064.
Amieva H, Phillips LH, Della Sala S, Henry JD (2004). Inhibitory functioning in Alzheimer’s disease. Brain, 127: 949-964.
Rankin KP, Gorno-Tempini ML, Allison SC, Stanley CM, Glenn S, Weiner MW,et al (2006). Structural anatomy of empathy in neurogenerative disease. Brain, 129: 2945-2956.
Reynaud E, Guedj E, Souville M, Trousselard M, Zendjidjian X, Khoury-Malhame ME,et al. (2013). Relationship between emotional experience and resilience: An fMRI study in fire-fighters. Neuropsychologia, 51: 845-849.
Tugade MM, Fredrickson BL (2007). Regulation of Positive Emotions: Emotion Regulation Strategies that Promote Resilience. J Happiness Stud, 8: 311-333.
Sands LP, Ferreira P, Stewart AL, Brod M, Yaffe K (2004). What explains differences between dementia patients’ and their caregivers’ ratings of patient’s quality of life? Am J Geriatr Psychiatry, 12: 272-280.
Ready RE, Carvalho JO, Green RC, Gavett BE, Stern RA (2011). The structure and validity of self-reported affect in mild cognitive impairment and mild Alzheimer’s disease. Int Psychogeriatr. 23: 887-898.
Forsell Y, Wingblad B (1998). Major Depression in a Population of Demented and Nondemented Older People: Prevalence and Correlates. J Am Geriatr Soc, 46: 27-30.
Manthorpe J, Iliffe S.Depression in later life. London and Philadelphia: Jessica Kingsley Publisher; 2005.
Feinstein JS, Duff MC, Tranel, D (2010). Sustained experience of emotion after loss of memory in patients with amnesia. Proc Natl Acad Sci (USA), 107: 7674-7679.
Sin NL, Lyubomirsky S (2009). Enhancing well-being and alleviating depressive symptoms with positive psychology interventions: A practice-friendly meta-analysis. J Clin Psychol, 65: 467-487.
Bakker AB, Schaufeli WB, Sixma HJ, Bosveld W, van Dierendonck D (2000). Patient demands lack of reciprocity, and burnout: A ﬁve-year longitudinal study among general practitioners. J Organ Behav, 21: 425-441.
Takahashi K, Iwase M, Yamashita K, Tatsumoto Y, Ue H, Kuratsune H,et al. (2001). The elevation of natural killer cell activity induced by laughter in a crossover designed study. Int J Mol Med, 8:645-50.
Hayashi K, Hayashi T, Iwanaga S, Kawai K, Ishii H, Shoji S,et al (2003). Laughter lowered the increase in postprandial blood glucose. Diabetes Care. 26:1651-1652.
Stuber M, Hilber SD, Mintzer LL, Castaneda M, Glover D, Zeltzer L (2009). Laughter, humor and pain perception in children: A pilot study. Evid-Based Compl Alt, 6:271-276.
Mather M, Carstensen LL (2005). Aging and motivated cognition: the positivity effect in attention and memory. Trends Cogn Sci, 9: 496-502.
Phillips LH, Scott C, Henry JD, Mowat D, Bell, JS (2010). Emotion perception in Alzheimer’s disease and mood disorder in old age. Psychol Aging, 25: 38-47.
Wiechetek OM, Schenk F, Baenziger T, von Gunten A. (2011). An exploratory study on facial emotion recognition capacity in beginning Alzheimer’s disease. Eur Neurol 65: 361-367.
Maki Y, Yoshida H, Yamaguchi T, Yamaguchi H (2013). Relative preservation of the recognition of positive facial expression “happiness” in Alzheimer’s disease. Int Psychogeriatr. 25: 105-110.
Carton JS, Kessler EA, Pape CL (1999). Nonverbal decoding skills and relationship well-being in adults. J Nonverbal Behav, 23:91-100.
Addington J, Saeedi H, Addington D (2006). Facial affect recognition: Amediator between cognitive and social functioning in psychosis? Schizophr Res, 85: 142-150.
Bornhofen C, McDonald S (2008). Emotion perception deficits following traumatic brain injury: A review of the evidence and rationale for intervention. J Int Neuropsychol Soc, 14: 511-525.
Werheid K, McDonald RS, Simmons-Stern N, Ally BA, Budson AE (2011). Familiar smiling faces in Alzheimer’s disease: Understanding the positivity-related recognition bias. Neuropsychologia. 49: 2935-2940.
Schacter DL, Addis DR (2007). Constructive memory: The ghosts of past and future. Nature, 455: 27.
Schacter DL, Addis DR, Buckner RL (2007). Remembering the past to imagine the future: the prospective brain. Nat Rev Neurosci, 8: 657-661.
Budson AE, Desikan R, Daffner KR, Schacter DL (2000). When false recognition is unopposed by true recognition: Gist-based memory distortion in Alzheimer’s disease. Neuropsychology, 14: 277-287
Zhang F, Geng HY (2010). What can false memory tell us about memory impairments in Alzheimer’s disease? Chin Sci Bull, 55: 3989-3997.
Klein-Koerkamp Y, Baciu M, Hot P (2012). Preserved and impaired emotional memory in Alzheimer’s disease. Front Psychology, 3: 331.
Dixon RA, Gould ON (1998). Younger and Older Adults Collaborating on Retelling Everyday Stories. Appl Dev Sci, 2: 160-171.
Isaacowitz DM, Choi Y (2011). The Malleability of Age-Related Positive Gaze Preferences: Training To Change Gaze and Mood. Emotion, 11: 90-100.
Wadlinger HA, Isaacowitz DM (2010). Fixing Our Focus: Training attention to regulate rmotion. Pers Soc Psychol Rev, 15: 75-102.
Hot P, Klein-Koerkamp Y, Borg C, Richard-Mornas A, Adeline AP, Zsoldos I,et al (2013). Fear recognition impairment in early-stage Alzheimer’s disease: When focusing on the eyes region improves performance. Brain Cognition, 82: 25-34.