Aging and disease

Transplantation of ACE2^- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia Zikuan Leng, Rongjia Zhu, Wei Hou, Yingmei Feng, Yanlei Yang, Qin Han, Guangliang Shan, Fanyan Meng, Dongshu Du, Shihua Wang, Junfen Fan, Wenjing Wang, Luchan Deng, Hongbo Shi, Hongjun Li, Zhongjie Hu, Fengchun Zhang, Jinming Gao, Hongjian Liu, Xiaoxia Li, Yangyang Zhao, Kan Yin, Xijing He, Zhengchao Gao, Yibin Wang, Bo Yang, Ronghua Jin, Ilia Stambler, Lee Wei Lim, Huanxing Su, Alexey Moskalev, Antonio Cano, Sasanka Chakrabarti, Kyung-Jin Min, Georgina Ellison-Hughes, Calogero Caruso, Kunlin Jin, Robert Chunhua Zhao: 2020, 11 (2): 216-228 | DOI: 10.14336/AD.2020.0228; PDF (1473KB)
Supplement; 1. Supplementary data.pdf (1202KB)

Five-Minute Cognitive Test as A New Quick Screening of Cognitive Impairment in The Elderly Jie Zhang, Lijun Wang, Xia Deng, Guoqiang Fei, Lirong Jin, Xiaoli Pan, Liuhan Cai, Anthony D Albano, Chunjiu Zhong: 2019, 10 (6): 1258-1269 | DOI: 10.14336/AD.2019.0115; PDF (1314KB)

The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress Boris Decourt, Gary X D’Souza, Jiong Shi, Aaron Ritter, Jasmin Suazo, Marwan N Sabbagh: 2022, 13 (1): 37-60 | DOI: 10.14336/AD.2021.0529; PDF (1536KB)

Dopamine Receptors and Neurodegeneration: 2015, 6 (5): 349-368 | DOI: 10.14336/AD.2015.0330; PDF (1415KB)

Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals Cyrus A. Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala: | DOI: 10.14336/AD.2023.0820; PDF (1477KB)

NF-κB in Aging and Disease Jeremy S. Tilstra, Cheryl L. Clauson, Laura J. Niedernhofer, Paul D. Robbins: 2011, 2 (6): 449-465; PDF (1175KB)

Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination Sankha Shubhra Chakrabarti, Ashutosh Tiwari, Sumit Jaiswal, Upinder Kaur, Ishan Kumar, Amit Mittal, Anup Singh, Kunlin Jin, Sasanka Chakrabarti: 2022, 13 (3): 633-636 | DOI: 10.14336/AD.2021.1102; PDF (363KB)

Dizziness and Imbalance in the Elderly: Age-related Decline in the Vestibular System Shinichi Iwasaki, Tatsuya Yamasoba: 2015, 6 (1): 38-47 | DOI: 10.14336/AD.2014.0128; PDF (457KB)

Modern Biological Theories of Aging Kunlin Jin: 2010, 1 (2): 72-74; PDF (291KB)

COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile Sadanand Fulzele, Bikash Sahay, Ibrahim Yusufu, Tae Jin Lee, Ashok Sharma, Ravindra Kolhe, Carlos M Isales: 2020, 11 (3): 509-522 | DOI: 10.14336/AD.2020.0428; PDF (793KB)
Supplement; 1. Supplementary data.pdf (970KB)

DeepMAge: A Methylation Aging Clock Developed with Deep Learning Fedor Galkin, Polina Mamoshina, Kirill Kochetov, Denis Sidorenko, Alex Zhavoronkov: 2021, 12 (5): 1252-1262 | DOI: 10.14336/AD.2020.1202; PDF (742KB)
Supplement; 1. Supplementary data.pdf (2088KB)

Metabolic Syndrome, Aging and Involvement of Oxidative Stress Francesca Bonomini, Luigi Fabrizio Rodella, Rita Rezzani: 2015, 6 (2): 109-120 | DOI: 10.14336/AD.2014.0305; PDF (571KB)

Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic Ping Liu, Haiping Zhao, Yumin Luo: 2017, 8 (6): 868-886 | DOI: 10.14336/AD.2017.0816; PDF (1198KB)

The Critical Need to Promote Research of Aging and Aging-related Diseases to Improve Health and Longevity of the Elderly Population Kunlin Jin, James W. Simpkins, Xunming Ji, Miriam Leis, Ilia Stambler: 2015, 6 (1): 1-5 | DOI: 10.14336/AD.2014.1210; PDF (734KB)

Phenylketonuria Pathophysiology: on the Role of Metabolic Alterations: 2015, 6 (5): 390-399 | DOI: 10.14336/AD.2015.0827; PDF (874KB)

Mechanism of Ferroptosis: A Potential Target for Cardiovascular Diseases Treatment Jie Ju, Ya-nan Song, Kun Wang: 2021, 12 (1): 261-276 | DOI: 10.14336/AD.2020.0323; PDF (962KB)

Low level of Vitamin C and dysregulation of Vitamin C transporter might be involved in the severity of COVID-19 Infection Taylor Patterson, Carlos M Isales, Sadanand Fulzele: 2021, 12 (1): 14-26 | DOI: 10.14336/AD.2020.0918; PDF (555KB)

New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases Yu-Qing Ni, You-Shuo Liu: 2021, 12 (8): 1948-1963 | DOI: 10.14336/AD.2021.0603; PDF (645KB)

Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia Ashok K Shetty: 2020, 11 (2): 462-464 | DOI: 10.14336/AD.2020.0301; PDF (212KB)

Sleep Disorders in Stroke: An Update on Management Hongxia Cai, Xiao-Ping Wang, Guo-Yuan Yang: 2021, 12 (2): 570-585 | DOI: 10.14336/AD.2020.0707; PDF (528KB)

Hypoglycemia in Older People - A Less Well Recognized Risk Factor for Frailty Ahmed H Abdelhafiz, Leocadio Rodríguez-Mañas, John E. Morley, Alan J Sinclair: 2015, 6 (2): 156-167 | DOI: 10.14336/AD.2014.0330; PDF (698KB)

The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks Jan R. Aunan, William C Cho, Kjetil Søreide: 2017, 8 (5): 628-642 | DOI: 10.14336/AD.2017.0103; PDF (1005KB)

Insulin, IGF-1 and longevity Diana van Heemst: 2010, 1 (2): 147-157; PDF (637KB)

Aging and Cardiac Fibrosis Anna Biernacka, Nikolaos G Frangogiannis: 2011, 2 (2): 158-173; PDF (830KB)

The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease: 2015, 6 (5): 331-341 | DOI: 10.14336/AD.2015.0825; PDF (849KB)

Emerging Anti-Aging Strategies - Scientific Basis and Efficacy Ashok K. Shetty, Maheedhar Kodali, Raghavendra Upadhya, Leelavathi N. Madhu: 2018, 9 (6): 1165-1184 | DOI: 10.14336/AD.2018.1026; PDF (481KB)
Supplement; 1. .pdf (553KB)

Metabolic Strategies in Healthcare: A New Era Matthew CL Phillips: 2022, 13 (3): 655-672 | DOI: 10.14336/AD.2021.1018; PDF (855KB)

Depression in the Elderly: Clinical Features and Risk Factors Gülfizar Sözeri-Varma: 2012, 3 (6): 465-471; PDF (398KB)

Hyperglycemic Stress and Carbon Stress in Diabetic Glucotoxicity Xiaoting Luo, Jinzi Wu, Siqun Jing, Liang-Jun Yan: 2016, 7 (1): 90-110 | DOI: 10.14336/AD.2015.0702; PDF (1213KB)

Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: An Update Feng Zhang, Long Niu, Xinyao Liu, Yufei Liu, Song Li, Huan Yu, Weidong Le: 2020, 11 (2): 315-326 | DOI: 10.14336/AD.2019.0324; PDF (608KB)

Reactive Astrocytes in Neurodegenerative Diseases Kunyu Li, Jiatong Li, Jialin Zheng, Song Qin: 2019, 10 (3): 664-675 | DOI: 10.14336/AD.2018.0720; PDF (730KB)

Relationship between Hypothyroidism and Endometrial Cancer Yiqin Wang, Rong Zhou, Jianliu Wang: 2019, 10 (1): 190-196 | DOI: 10.14336/AD.2018.0224; PDF (317KB)

Transcranial Near Infrared Light Stimulations Improve Cognition in Patients with Dementia Damir Nizamutdinov, Xiaoming Qi, Marvin H Berman, Gordon Dougal, Samantha Dayawansa, Erxi Wu, S. Stephen Yi, Alan B Stevens, Jason H Huang: 2021, 12 (4): 954-963 | DOI: 10.14336/AD.2021.0229; PDF (459KB)

Sirtuins and their Biological Relevance in Aging and Age-Related Diseases Lijun Zhao, Jianzhong Cao, Kexin Hu, Xiaodong He, Dou Yun, Tanjun Tong, Limin Han: 2020, 11 (4): 927-945 | DOI: 10.14336/AD.2019.0820; PDF (655KB)

Herba Cistanches: Anti-aging Ningqun Wang, Shaozhen Ji, Hao Zhang, Shanshan Mei, Lumin Qiao, Xianglan Jin: 2017, 8 (6): 740-759 | DOI: 10.14336/AD.2017.0720; PDF (1134KB)

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology of Alzheimer’s Disease Carolyn C. Rudy, Holly C. Hunsberger, Daniel S. Weitzner, Miranda N. Reed: 2015, 6 (2): 131-148 | DOI: 10.14336/AD.2014.0423; PDF (915KB)

Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment Sasanka Chakrabarti, Vineet Kumar Khemka, Anindita Banerjee, Gargi Chatterjee, Anirban Ganguly, Atanu Biswas: 2015, 6 (4): 282-299 | DOI: 10.14336/AD.2014.002; PDF (1071KB)

Eating Disorders in Late-life Antonina Luca, Maria Luca, Carmela Calandra2: 2015, 6 (1): 48-55 | DOI: 10.14336/AD.2014.0124; PDF (492KB)

The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases Wenjun Tu, Hong Wang, Song Li, Qiang Liu, Hong Sha: 2019, 10 (3): 637-651 | DOI: 10.14336/AD.2018.0513; PDF (478KB)

Cell Cycle Deficits in Neurodegenerative Disorders: Uncovering Molecular Mechanisms to Drive Innovative Therapeutic Development Chitra Joseph, Abubakar Siddiq Mangani, Veer Gupta, Nitin Chitranshi, Ting Shen, Yogita Dheer, Devaraj KB, Mehdi Mirzaei, Yuyi You, Stuart L Graham, Vivek Gupta: 2020, 11 (4): 946-966 | DOI: 10.14336/AD.2019.0923; PDF (710KB)

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