Aging and disease

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05 June 2018. VOL 9, ISSUE 3 Previous Issue Next Issue

Orginal Article

Anserine/Carnosine Supplementation Preserves Blood Flow in the Prefrontal Brain of Elderly People Carrying APOE e4
Qiong Ding, Kitora Tanigawa, Jun Kaneko, Mamoru Totsuka, Yoshinori Katakura, Etsuko Imabayashi, Hiroshi Matsuda, Tatsuhiro Hisatsune

2018, 9 (3): 334-345 | DOI: 10.14336/AD.2017.0809

PDF (789KB)
Association of ApoE Genetic Polymorphism and Type 2 Diabetes with Cognition in Non-Demented Aging Chinese Adults: A Community Based Cross-Sectional Study
Jie Zhen, Tong Lin, Xiaochen Huang, Huiqiang Zhang, Shengqi Dong, Yifan Wu, Linlin Song, Rong Xiao, Linhong Yuan

2018, 9 (3): 346-357 | DOI: 10.14336/AD.2017.0715

PDF (649KB)
Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology
Jiao Lu, Xuefeng Duan, Wenming Zhao, Jing Wang, Haoyu Wang, Kai Zhou, Min Fang

2018, 9 (3): 358-373 | DOI: 10.14336/AD.2017.0701

PDF (1553KB)
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain
Yali Chen, Mengmei Yin, Xuejin Cao, Gang Hu, Ming Xiao

2018, 9 (3): 374-390 | DOI: 10.14336/AD.2017.0706

PDF (1562KB)
Evaluation of Hyperbaric Oxygen Treatment in Acute Traumatic Spinal Cord Injury in Rats Using Diffusion Tensor Imaging
Wenzhi Sun, Jiewen Tan, Zhuo Li, Shibao Lu, Man Li, Chao Kong, Yong Hai, Chunjin Gao, Xuehua Liu

2018, 9 (3): 391-400 | DOI: 10.14336/AD.2017.0726

PDF (987KB)
Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP
Xiangrong Liu, Shaohong Wen, Shunying Zhao, Feng Yan, Shangfeng Zhao, Di Wu, Xunming Ji

2018, 9 (3): 401-411 | DOI: 10.14336/AD.2017.0703

PDF (1012KB)
Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation
Can Zhang, Nicole R. Brandon, Kerryann Koper, Pei Tang, Yan Xu, Huanyu Dou

2018, 9 (3): 412-425 | DOI: 10.14336/AD.2017.0926

PDF (1450KB)
Prehospital Notification Procedure Improves Stroke Outcome by Shortening Onset to Needle Time in Chinese Urban Area
Sheng Zhang, Jungen Zhang, Meixia Zhang, Genlong Zhong, Zhicai Chen, Longting Lin, Min Lou

2018, 9 (3): 426-434 | DOI: 10.14336/AD.2017.0601

PDF (728KB)
Repetitive Element DNA Methylation is Associated with Menopausal Age
Sha Lu, Zheng Niu, Yueming Chen, Qiaofeng Tu, Yue Zhang, Wenli Chen, Wenjuan Tong, Zhifen Zhang

2018, 9 (3): 435-443 | DOI: 10.14336/AD.2017.0810

PDF (697KB)
Progression of White Matter Hyperintensities Contributes to Lacunar Infarction
Xin Xu, Yuanyuan Gao, Renyuan Liu, Lai Qian, Yan Chen, Xiaoying Wang, Yun Xu

2018, 9 (3): 444-452 | DOI: 10.14336/AD.2017.0808

PDF (747KB)
APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats
Tao Yan, Poornima Venkat, Michael Chopp, Alex Zacharek, Peng Yu, Ruizhuo Ning, Xiaoxi Qiao, Mark R. Kelley, Jieli Chen

2018, 9 (3): 453-466 | DOI: 10.14336/AD.2017.1130

PDF (1718KB)
Splenectomy Fails to Provide Long-Term Protection Against Ischemic Stroke
Yuanyuan Ran, Zongjian Liu, Shuo Huang, Jiamei Shen, Fengwu Li, Wenxiu Zhang, Chen Chen, Xiaokun Geng, Zhili Ji, Huishan Du, Xiaoming Hu

2018, 9 (3): 467-479 | DOI: 10.14336/AD.2018.0130

PDF (2135KB)
The Value of Contrast-Enhanced Ultrasonography Combined with Real-Time Strain Elastography in the Early Diagnosis of Prostate Cancer
Ying Chang, Jingchun Yang, Hua Hong, Huijuan Ma, Xin Cui, Li Chen

2018, 9 (3): 480-488 | DOI: 10.14336/AD.2017.0704

PDF (1434KB)
Frailty in Older Adults with Cardiovascular Disease: Cause, Effect or Both?
Emma EF. Kleipool, Emiel O. Hoogendijk, Marijke C. Trappenburg, M. Louis Handoko, Martijn Huisman, Mike JL. Peters, Majon Muller

2018, 9 (3): 489-497 | DOI: 10.14336/AD.2017.1125

PDF (411KB)
The Short-term Prognostic Value of the Triglyceride-to-high-density Lipoprotein Cholesterol Ratio in Acute Ischemic Stroke
Qi-Wen Deng, Shuo Li, Huan Wang, Leix Lei, Han-Qing Zhang, Zheng-Tian Gu, Fang-Lan Xing, Fu-Ling Yan

2018, 9 (3): 498-506 | DOI: 10.14336/AD.2017.0629

PDF (799KB)

Review Article

Effects of Therapeutic Hypothermia Combined with Other Neuroprotective Strategies on Ischemic Stroke: Review of Evidence
Zheng Zhang, Linlei Zhang, Yuchuan Ding, Zhao Han, Xunming Ji

2018, 9 (3): 507-522 | DOI: 10.14336/AD.2017.0628

PDF (506KB)
BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders
Ting Shen, Yuyi You, Chitra Joseph, Mehdi Mirzaei, Alexander Klistorner, Stuart L. Graham, Vivek Gupta

2018, 9 (3): 523-536 | DOI: 10.14336/AD.2017.0717

PDF (469KB)
Mammalian Sterile20-like Kinases: Signalings and Roles in Central Nervous System
Sheng Chen, Yuanjian Fang, Shenbin Xu, Cesar Reis, Jianmin Zhang

2018, 9 (3): 537-552 | DOI: 10.14336/AD.2017.0702

PDF (807KB)

Cover Illustration

05 June 2018. Vol.9 No.3
ACS preserves blood flow in the prefrontal brain of elderly people. Location of differential longitudinal changes in brain perfusion (red) in the active and placebo groups, on a brain montage from the SPM platform based on equivalent calculations to those in Fig. 3. In the active group, blood flow in these areas was elevated in the follow-up MRI scan.

[Detail]

Cover Illustration

ACS preserves blood flow in the prefrontal brain of elderly people. Location of differential longitudinal changes in brain perfusion (red) in the active and placebo groups, on a brain montage from the SPM platform based on equivalent calculations to those in Fig. 3. In the active group, blood flow in these areas was elevated in the follow-up MRI scan.