09 January 2016. Vol.7 No.3
Figure. The effect of age on cortical thickness in healthy Ccontrols and Parkinson’s disease. Green highlighted regions represent those regions that follow a linear rate of atrophy. Red highlighted regions depict rates of early decline (decreasing quickly at first, then stabilizing), while regions in yellow depict regions that atrophy faster over time (stable at first, then decreasing quickly). Regions in orange depict early decline, stabilization, followed by late decline, which is notable in later decades of life (early-stable-late). PD patients show characteristic frontal cortical thinning with age.
Regions in yellow depict regions that atrophy faster over time (concave down, decreasing curve or late decline). Regions in blue shown in the right column are regions showing an interaction between age and disease.