Aging and disease

Table of Content

01 October 2017. VOL 8, ISSUE 5 Previous Issue Next Issue

Original Article

Aging Systemic Milieu Impairs Outcome after Ischemic Stroke in Rats
Mengxiong Pan, Peng Wang, Chengcai Zheng, Hongxia Zhang, Siyang Lin, Bei Shao, Qichuan Zhuge, Kunlin Jin

2017, 8 (5): 519-530 | DOI: 10.14336/AD.2017.0710

PDF (1568KB)
Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids
Mengfei Cai, Wenting Zhang, Zhongfang Weng, R. Anne Stetler, Xiaoyan Jiang, Yejie Shi, Yanqin Gao, Jun Chen

2017, 8 (5): 531-545 | DOI: 10.14336/AD.2017.0520

PDF (1663KB)
Parity History Determines a Systemic Inflammatory Response to Spread of Ovarian Cancer in Naturally Aged Mice
Ulises Urzua, Carlos Chacon, Luis Lizama, Sebastián Sarmiento, Pía Villalobos, Belén Kroxato, Katherine Marcelain, María-Julieta Gonzalez

2017, 8 (5): 546-557 | DOI: 10.14336/AD.2017.0110

PDF (820KB)
Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai
Sheng Peng, Ting Shen, Jie Liu, Brian Tomlinson, Huimin Sun, Xiaoli Chen, Paul Chan, YaShu Kuang, Liang Zheng, Hong Wu, Xugang Ding, Dingguang Qian, Yixin Shen, Pingjin Gao, Huimin Fan, Zhongmin Liu, Yuzhen Zhang

2017, 8 (5): 558-569 | DOI: 10.14336/AD.2016.1220

PDF (819KB)

Review

The Pathogenesis of Ossification of the Posterior Longitudinal Ligament
Liang Yan, Rui Gao, Yang Liu, Baorong He, Shemin Lv, Dingjun Hao

2017, 8 (5): 570-582 | DOI: 10.14336/AD.2017.0201

PDF (938KB)
Recognizing Degenerative Aging as a Treatable Medical Condition: Methodology and Policy
Ilia Stambler

2017, 8 (5): 583-589 | DOI: 10.14336/AD.2017.0130

PDF (789KB)
Age-related Impairment of Vascular Structure and Functions
Xianglai Xu, Brian Wang, Changhong Ren, Jiangnan Hu, David A. Greenberg, Tianxiang Chen, Liping Xie, Kunlin Jin

2017, 8 (5): 590-610 | DOI: 10.14336/AD.2017.0430

PDF (1248KB)
Cancer and Aging - the Inflammatory Connection
Adar Zinger, William C Cho, Arie Ben-Yehuda

2017, 8 (5): 611-627 | DOI: 10.14336/AD.2016.1230

PDF (852KB)
The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks
Jan R. Aunan, William C Cho, Kjetil Søreide

2017, 8 (5): 628-642 | DOI: 10.14336/AD.2017.0103

PDF (1005KB)
Skin Cancer Epidemics in the Elderly as An Emerging Issue in Geriatric Oncology
Simone Garcovich, Giuseppe Colloca, Pietro Sollena, Bellieni Andrea, Lodovico Balducci, William C. Cho, Roberto Bernabei, Ketty Peris

2017, 8 (5): 643-661 | DOI: 10.14336/AD.2017.0503

PDF (786KB)
Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect
Tia R. Tidwell, Kjetil Søreide, Hanne R. Hagland

2017, 8 (5): 662-676 | DOI: 10.14336/AD.2017.0713

PDF (1084KB)
Ovarian Cancer Management in the Oldest Old: Improving Outcomes and Tailoring Treatments
Lucia Tortorella, Giuseppe Vizzielli, Domenico Fusco, William C. Cho, Roberto Bernabei, Giovanni Scambia, Giuseppe Colloca

2017, 8 (5): 677-684 | DOI: 10.14336/AD.2017.0607

PDF (854KB)

Editorial

Molecular Connections of Aging and Cancer
William C. Cho

2017, 8 (5): 685-687 | DOI: 10.14336/AD.2017.0822

PDF (475KB)

Cover Illustration

01 October 2017. Vol.8 No.5
Figure 1. Administration of old plasma into young ischemic rats worsensyoungyoungwrosew were outcomeafter ischemic stroke . (A) Schematic illustrating intraperitonealinjection of young (2-month-old) or old (22-month-old) plasma into young ischemic rats 1 hr after onset of ischemia, twice per day for 3 days. (B) Infarct areas (white) in TTC-(red) stained coronal brain section from vehicle, young and old plasma-treated rats at 3 days after stroke.

[Detail]

Cover Illustration

Figure 1. Administration of old plasma into young ischemic rats worsensyoungyoungwrosew were outcomeafter ischemic stroke . (A) Schematic illustrating intraperitonealinjection of young (2-month-old) or old (22-month-old) plasma into young ischemic rats 1 hr after onset of ischemia, twice per day for 3 days. (B) Infarct areas (white) in TTC-(red) stained coronal brain section from vehicle, young and old plasma-treated rats at 3 days after stroke.

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