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Just Accepted
The papers published below have been examined by the peer-review process and accepted for publication in Aging and Disease. A “Just Accepted” paper is published online shortly after its acceptance, which allows authors to make their results available to the research community as soon as possible after acceptance. When the final version appears, the version of early edition is replaced with the final version, and the paper is moved to the appropriate issue on the Aging and Disease website. The paper will no longer appear in the “Just Accepted”. However, all links (the URL) will not change. “Just Accepted” papers are citable from that date they are posted. To cite this manuscript please include its Digital Object Identifier (DOI), which is identical for all formats of publication.
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DNA Methylation Modulates Aging Process in Adipocytes
Hao Xie, Xin Liu, Qing Zhou, Teng Huang, Lu Zhang, Jia Gao, Yuhan Wang, Yanjun Liu, Tong Yan, Shu Zhang, Cong-Yi Wang
Aging and disease    DOI: 10.14336/AD.2021.0904
Accepted: 07 September 2021

The Therapeutic Potential of tRNA-derived Small RNAs in Neurodegenerative Disorders
Haihua Tian, Zhenyu Hu, Chuang Wang
Aging and disease    DOI: 10.14336/AD.2021.0903
Accepted: 06 September 2021

Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal
Alba M. Garcia-Serrano,Adélaïde A. Mohr,Juliette Philippe,Cecilia Skoug,Peter Spégel,João M.N. Duarte
Aging and disease    DOI: 10.14336/AD.2021.0720
Accepted: 03 September 2021

Role of Forkhead Box Protein O1 (FoxO1) in Stroke: A Literature Review
Sichao Guo, Ruchi Mangal, Chaitu Dandu, Xiaokun Geng, Yuchuan Ding
Aging and disease    DOI: 10.14336/AD.2021.0826
Accepted: 30 August 2021

Autophagy and Diabetic Encephalopathy: Mechanistic Insights and Potential Therapeutic Implications
Li-zhen Cheng, Wei Li, Yi-xin Chen, Yi-jia Lin, Ya Miao
Aging and disease    DOI: 10.14336/AD.2021.0823
Accepted: 27 August 2021

Synergistic Effects of Multiple Factors Involved in COVID-19-dependent Muscle Loss
Nicholas Cantu, Sagar Vyavahare, Sandeep Kumar, Jie Chen, Ravindra Kolhe, Carlos M. Isales, Mark Hamrick, Sadanand Fulzele
Aging and disease    DOI: 10.14336/AD.2021.0817
Accepted: 24 August 2021

Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells
Chiara de Lucia,Tytus Murphy,Aleksandra Maruszak,Paul Wright,Timothy R. Powell,Naomi Hartopp,Simone de Jong,Michael J O'Sullivan,Gerome Breen,Jack Price,Simon Lovestone,Sandrine Thuret
Aging and disease    DOI: 10.14336/AD.2021.0409
Accepted: 23 August 2021

Intrinsic Capacity in Older Adults: Recent Advances
Yaru Zhou, Lina Ma*
Aging and disease    DOI: 10.14336/AD.2021.0818
Accepted: 21 August 2021
Online available: 21 August 2021

ACE2 and COVID-19 Susceptibility and Severity
Ming Zheng
Aging and disease    DOI: 10.14336/AD.2021.0805
Accepted: 18 August 2021

Potential Effect of the Circadian Clock on Erectile Dysfunction
Tao Li, Yunjin Bai, Yiting Jiang, Kehua Jiang, Ye Tian, Zhen Wang, Yong Ban, Xiangyi Liang, Guangheng Luo, Fa Sun
Aging and disease    DOI: 10.14336/AD.2021.0728
Accepted: 13 August 2021

The Pathogenetic Dilemma of Post-COVID-19 Mucormycosis in India
Sankha Shubhra Chakrabarti, Upinder Kaur, Sushil Kumar Aggarwal, Ahalya Kanakan, Adesh Saini, Bimal Kumar Agrawal, Kunlin Jin, Sasanka Chakrabarti
Aging and disease    DOI: 10.14336/AD.2021.0811
Accepted: 12 August 2021

Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?
Chul-Kyu Kim, Perminder S. Sachdev, Nady Braidy
Aging and disease    DOI: 10.14336/AD.2021.0705
Accepted: 10 August 2021

Comparative Analysis of Aducanumab, Zagotenemab and Pioglitazone as Targeted Treatment Strategies for Alzheimer’s Disease
Morteza Abyadeh, Vivek Gupta, Veer Gupta, Nitin Chitranshi, Yunqi Wu, Ardeshir Amirkhani, Anna Meyfour, Samran Sheriff, Ting Shen, Kunal Dhiman, Ghasem H. Salekdeh, Paul A Haynes, Stuart L Graham, Mehdi Mirzaei
Aging and disease    DOI: 10.14336/AD.2021.0719
Accepted: 09 August 2021

Supercentenarians that Survived COVID-19
George Siopis
Aging and disease    DOI: 10.14336/AD.2021.0806
Accepted: 07 August 2021

Aquaporin-4 and Cognitive Disorders
Yifan Wang, Chuyi Huang, Qihao Guo, Heling Chu
Aging and disease    DOI: 10.14336/AD.2021.0731
Accepted: 04 August 2021

Animal Models of Epilepsy: A Phenotype-oriented Review
Yilin Wang, Penghu Wei, Feng Yan, Yumin Luo, Guoguang Zhao
Aging and disease    DOI: 10.14336/AD.2021.0723
Accepted: 03 August 2021

Irreversibility of Pulmonary Fibrosis
Qing Yang Yu, Xiao Xiao Tang
Aging and disease    DOI: 10.14336/AD.2021.0730
Accepted: 03 August 2021

Mammalian AKT, the Emerging Roles on Mitochondrial Function in Diseases
Xiaoxian Xie, Ruonan Shu, Chunan Yu, Zhengwei Fu, Zezhi Li
Aging and disease    DOI: 10.14336/AD.2021.0729
Accepted: 02 August 2021

Emerging Roles of Ceramide in Cardiovascular Diseases
Hongyang Shu, Yizhong Peng, Weijian Hang, Na Li, Ning Zhou, Dao Wen Wang
Aging and disease    DOI: 10.14336/AD.2021.0710
Accepted: 26 July 2021

Regulatory T cells in COVID-19
Huan Wang, Zhao Wang, Wen Cao, Qianqian Wu, Yujia Yuan, Xiangjian Zhang
Aging and disease    DOI: 10.14336/AD.2021.0709
Accepted: 26 July 2021

Effect of COVID-19 on Geriatric Medical Services in China
Qingqing Yin, Xueying Liu, Chengcheng Huang, Wenkai Bi, Runfa Zhou, Renjun Lv
Aging and disease    DOI: 10.14336/AD.2021.0703
Accepted: 17 July 2021

Pharmacological Blockade of NLRP3 Inflammasome/IL-1β-Positive Loop Mitigates Endothelial Cell Senescence and Dysfunction
Alejandra Romero, Pilar Dongil, Inés Valencia, Susana Vallejo, Álvaro San Hipólito-Luengo, Guillermo Díaz-Araya, José L. Bartha, María M. González-Arlanzón, Fernando Rivilla, Fernando de la Cuesta, Carlos F. Sánchez-Ferrer, Concepción Peiró
Aging and disease    DOI: 10.14336/AD.2021.0617
Accepted: 16 July 2021

Review on Laser Technology in Intravascular Imaging and Treatment
Jing Li, Ce Shang, Yao Rong, Jingxuan Sun, Yuan Cheng, Boqu He, Zihao Wang, Ming Li, Jianguo Ma, Bo Fu, Xunming Ji
Aging and disease    DOI: 10.14336/AD.2021.0711
Accepted: 14 July 2021

Coagulation Disorders and Thrombosis in COVID-19 Patients and a Possible Mechanism Involving Endothelial Cells: A Review
An-tian Chen, Chen-yu Wang, Wen-ling Zhu, Wei Chen
Aging and disease    DOI: 10.14336/AD.2021.0704
Accepted: 11 July 2021

EP3 Receptor Deficiency Improves Vascular Remodeling and Cognitive Impairment in Cerebral Small Vessel Disease
Na Liu, Jie Tang, Yang Xue, Vincent Mok, Miaoyi Zhang, Xue Ren, Yilong Wang, Jianhui Fu
Aging and disease    DOI: 10.14336/AD.2021.0627
Accepted: 04 July 2021

Atrial Fibrillation Underlies Cardiomyocyte Senescence and Contributes to Deleterious Atrial Remodeling during Disease Progression
Ailiya Adili, Xiyu Zhu, Hailong Cao, Xinlong Tang, Yali Wang, Junxia Wang, Jian Shi, Qing Zhou, Dongjin Wang
Aging and disease    DOI: 10.14336/AD.2021.0619
Accepted: 29 June 2021

Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents
Benson OA. Botchway, Favour C. Okoye, Yili Chen, William E. Arthur, Marong Fang
Aging and disease    DOI: 10.14336/AD.2021.0616
Accepted: 18 June 2021

The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress
Boris Decourt, Gary X. D’Souza, Jiong Shi, Aaron Ritter, Jasmin Suazo, Marwan N. Sabbagh
Aging and disease    DOI: 10.14336/AD.2021.0529
Accepted: 18 June 2021

Challenges in Establishing Vaccine Induced Herd Immunity through Age Specific Community Vaccinations
Barsha Dassarma, Satyajit Tripathy, Matimbha Chabalala, Motlalepula Gilbert Matsabisa
Aging and disease    DOI: 10.14336/AD.2021.0611
Accepted: 16 June 2021

Chronic Limb Remote Ischemic Conditioning may have an Antihypertensive Effect in Patients with Hypertension
Wenting Guo, Changhong Ren, Bowei Zhang, Wenbo Zhao, Yu Gao, Wantong Yu, Xunming Ji
Aging and disease    DOI: 10.14336/AD.2021.0604
Accepted: 12 June 2021

The Effect of COVID-19-related Lockdowns on Diet and Physical Activity in Older Adults: A Systematic Review
Elisabeth Anne Larson, Karlen Stade Bader-Larsen, Faidon Magkos
Aging and disease    DOI: 10.14336/AD.2021.0606
Accepted: 08 June 2021

Bioenergetic Impairment in the Neuro-Glia-Vascular Unit: An Emerging Physiopathology during Aging
Minghao Yuan, Yangyang Wang, Shengyuan Wang, Zhenting Huang, Feng Jin, Qian Zou, Jing Li, Yinshuang Pu, Zhiyou Cai
Aging and disease    DOI: 10.14336/AD.2021.04017
Accepted: 07 June 2021

New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases
Yu-Qing Ni, You-Shuo Liu
Aging and disease    DOI: 10.14336/AD.2021.0603
Accepted: 07 June 2021

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors
Jing She, Rui Sheng, Zheng-Hong Qin
Aging and disease    DOI: 10.14336/AD.2021.0523
Accepted: 31 May 2021
Online available: 31 May 2021

Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level
Ying Liu, Lu Li, Khalid Timani, Carl White, Johnny J. He
Aging and disease    DOI: 10.14336/AD.2021.0528
Accepted: 30 May 2021

Depression and Dementia in Older Adults: A Neuropsychological Review
Syuichi Tetsuka
Aging and disease    DOI: 10.14336/AD.2021.0526
Accepted: 29 May 2021

A Unique Type of Highly-Activated Microglia Evoking Brain Inflammation via Mif/Cd74 Signaling Axis in Aged Mice
Chenghao Jin, Yijie Shao, Xiaotao Zhang, Jiani Xiang, Ruize Zhang, Zeyu Sun, Shuhao Mei, Jingyi Zhou, Jianmin Zhang, Ligen Shi
Aging and disease    DOI: 10.14336/AD.2021.0520
Accepted: 26 May 2021

A Systematic Review of Parkinson’s Disease Cluster Analysis Research
Renee M. Hendricks, Mohammad T. Khasawneh
Aging and disease    DOI: 10.14336/AD.2021.0519
Accepted: 23 May 2021

A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics Approach
Manojit Bhattacharya, Ashish Ranjan Sharma, Pratik Ghosh, Sang-Soo Lee, Chiranjib Chakraborty
Aging and disease    DOI: 10.14336/AD.2021.0518
Accepted: 22 May 2021

Dysfunction of the Blood-brain Barrier in Cerebral Microbleeds: from Bedside to Bench
Hai-ling Wang, Chun-lin Zhang, Yan-mei Qiu, An-qi Chen, Ya-nan Li, Bo Hu
Aging and disease    DOI: 10.14336/AD.2021.0514
Accepted: 20 May 2021

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