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ISSN 2152-5250
Since 2010
2016 impact factor: 4.648
5 year impact factor: 4.1
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Early edition
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A "Early edition" manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides "Early edition" as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the "Early edition" Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these "Early edition" manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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CLARITY for High-resolution Imaging and Quantification of Vasculature in the Whole Mouse Brain
Zhang Lin-Yuan,Lin *Pan,Pan Jiaji,Ma Yuanyuan,Wei Zhenyu,Jiang Lu,Wang Liping,Song Yaying,Wang Yongting,Zhang Zhijun,Jin Kunlin,Wang Qian,Yang Guo-Yuan
Aging and Disease    DOI: 10.14336/AD.2017.0613
Association of ApoE Genetic Polymorphism and Type 2 Diabetes with Cognition in Non-Demented Aging Chinese Adults: A Community Based Cross-Sectional Study
Zhen Jie,Lin Tong,Huang Xiaochen,Zhang Huiqiang,Dong Shengqi,Wu Yifan,Song Linlin,Xiao Rong,Yuan Linhong
Aging and Disease    DOI: 10.14336/AD.2017.0715
Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson’s Disease
Zhang Li,Hao Junwei,Zheng Yan,Su Ruijun,Liao Yajin,Gong Xiaoli
Aging and Disease    DOI: 10.14336/AD.2017.0831
BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders
Shen Ting,You Yuyi,Joseph Chitra,Mirzaei Mehdi,Klistorner Alexander,L. Graham Stuart,Gupta Vivek
Aging and Disease    DOI: 10.14336/AD.2017.0717
Synergistically Induced Hypothermia and Enhanced Neuroprotection by Pharmacological and Physical Approaches in Stroke
Zhang Jun,Liu Kaiyin,Elmadhoun Omar,Ji Xunming,Duan Yunxia,Shi Jingfei
Aging and Disease    DOI: 10.14336/AD.2017.08167
Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes
Tang Feng,Pan Meng-Hao,Lu Yujie,Wan Xiang,Zhang Yu,Sun Shao-Chen
Aging and Disease    DOI: 10.14336/AD.2017.0901
Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) on 3-tesla Normal Database: Diagnostic Accuracy in Two Independent Cohorts with Early Alzheimer’s Disease
Sone Daichi,Imabayashi Etsuko,Maikusa Norihide,Ogawa Masayo,Sato Noriko,Matsuda Hiroshi,Disease Neuroimaging Initiative Japanese-Alzheimer’s
Aging and Disease    DOI: 10.14336/AD.2017.0818
Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
Liu Ping,Zhao Haiping,Luo Yumin
Aging and Disease    DOI: 10.14336/AD.2017.0816
Repetitive Element DNA Methylation is Associated with Menopausal Age
Lu Sha,Niu Zheng,Chen Yueming,Tu Qiaofeng,Zhang Yue,Chen Wenli,Tong Wenjuan,Zhang Zhifen
Aging and Disease    DOI: 10.14336/AD.2017.0810
Anserine/Carnosine Supplementation Preserves Blood Flow in the Prefrontal Brain of Elderly People Carrying APOE e4
Ding Qiong,Tanigawa Kitora,Kaneko Jun,Totsuka Mamoru,Katakura Yoshinori,Imabayashi Etsuko,Matsuda Hiroshi,Hisatsune Tatsuhiro
Aging and Disease    DOI: 10.14336/AD.2017.0809
Progression of White Matter Hyperintensities Contributes to Lacunar Infarction
Xu Xin,Gao Yuanyuan,Liu Renyuan,Qian Lai,Chen Yan,Wang Xiaoying,Xu Yun
Aging and Disease    DOI: 10.14336/AD.2017.0808
Causes of Death in Chinese Patients with Multiple System Atrophy
Zhang LingYu,Cao Bei,Zou Yutong,Wei Qian-Qian,Ou RuWei,Liu Wanglin,Zhao Bi,Yang Jing,Wu Ying,Shang HuiFang
Aging and Disease    DOI: 10.14336/AD.2017.0711
Aging Systemic Milieu Impairs Outcome after Ischemic Stroke in Rats
Pan Mengxiong,Wang Peng,Zheng Chengcai,Zhang Hongxia,Lin Siyang,Shao Bei,Zhuge Qichuan,Jin Kunlin
Aging and Disease    DOI: 10.14336/AD.2017.0710
Evaluation of Hyperbaric Oxygen Treatment in Acute Traumatic Spinal Cord Injury in Rats Using Diffusion Tensor Imaging
Sun Wenzhi,Li Zhuo,Lu Shibao,Tan Jiewen,Li Man,Kong Chao,Hai Yong,Gao Chunjin,Liu Xuehua
Aging and Disease    DOI: 10.14336/AD.2017.0726
Lycium Barbarum: A Traditional Chinese Herb and A Promising Anti-Aging Agent
Gao Yanjie,Wei Yifo,Wang Yuqing,Gao Fang,Chen Zhigang
Aging and Disease    DOI: 10.14336/AD.2017.0725
Ginseng: An Nonnegligible Natural Remedy for Healthy Aging
Yang Yong,Ren Changhong,Zhang Yuan,Wu XiaoDan
Aging and Disease    DOI: 10.14336/AD.2017.07067
Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases
Zhao Haiping,Han Ziping,Li Guangwen,Zhang Sijia,Luo Yumin
Aging and Disease    DOI: 10.14336/AD.2017.0724
Herba Cistanches: Anti-aging
Wang Ningqun,Ji Shaozhen,Zhang Hao,Mei Shanshan,Qiao Lumin,Jin Xianglan
Aging and Disease    DOI: 10.14336/AD.2017.0720
Prehospital Notification Procedure Improves Stroke Outcome by Shortening Onset to Needle Time in Chinese Urban Area
Zhang Sheng,Zhang Jungen,Zhang Meixia,Zhong Genlong,Chen Zhicai,Lin Longting,Lou Min
Aging and Disease    DOI: 10.14336/AD.2017.0601
The Value of Contrast-Enhanced Ultrasonography Combined with Real-Time Strain Elastography in the Early Diagnosis of Prostate Cancer
Chang Ying, Yang Jingchun, Hong Hua, Ma Huijuan, Cui Xin, Chen Li
Aging and Disease    DOI: 10.14336/AD.2017.0704
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain
Chen Yali,Yin Mengmei,Cao Xuejin,Hu Gang,Xiao Ming
Aging and Disease    DOI: 10.14336/AD.2017.0706
Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP
Liu Xiangrong,Wen Shaohong,Zhao Shunying,Yan Feng,Zhao Shangfeng,Wu Di,Ji Xunming
Aging and Disease    DOI: 10.14336/AD.2017.0703
Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect
Tia R. Tidwell, Kjetil S?reide, Hanne R. Hagland
Aging and Disease    DOI: 10.14336/AD.2017.0713
Glucocerebrosidase mRNA is Diminished in Brain of Lewy Body Diseases and Changes with Disease Progression in Blood
Perez-Roca Laia,Adame-Castillo Cristina,Campdelacreu Jaume,Ispierto Lourdes,Vilas Dolores,Rene Ramon,Alvarez Ramiro,Gascon-Bayarri Jordi,A. Serrano-Munoz Maria,Ariza Aurelio,Beyer Katrin
Aging and Disease    DOI: 10.14336/AD.2017.0505
Effects of Therapeutic Hypothermia Combined with Other Neuroprotective Strategies on Ischemic Stroke: Review of Evidence
Zhang Zheng,Zhang Linlei,Ding Yuchuan,Han Zhao,Ji Xunming
Aging and Disease    DOI: 10.14336/AD.2017.0628
The Short-term Prognostic Value of the Triglyceride-to-high-density Lipoprotein Cholesterol Ratio in Acute Ischemic Stroke
Qi-Wen Deng, Shuo Li, Huan Wang, Lei Zuo, Han-Qing Zhang, Zheng-Tian Gu, Fang-Lan Xing, Fu-Ling Yan
Aging and Disease    DOI: 10.14336/AD.2017.0629
Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology
Lu Jiao,Duan Xuefeng,Zhao Wenming,Wang Jing,Wang Haoyu,Zhou Kai,Fang Min
Aging and Disease    DOI: 10.14336/AD.2017.0701
Mammalian Sterile20-like Kinases: Signalings and Roles in Central Nervous System
Chen Sheng,Fang Yuanjian,Xu Shenbin,Reis Cesar,Zhang Jianmin
Aging and Disease    DOI: 10.14336/AD.2017.0702
Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction
Pedro Carrera-Bastos, óscar Picazo, Maelán Fontes-Villalba, Helios Pareja-Galeano, Staffan Lindeberg, Manuel Martínez-Selles, Alejandro Lucia, Enzo Emanuele
Aging and Disease    DOI: 10.14336/AD.2017.0630
Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-related Diseases via Anti-oxidation and AMPK Activation
Xu Zhifang,Feng Wei,Shen Qian,Yu Nannan,Yu Kun,Wang Shenjun,Chen Zhigang,Seiji Shioda,Guo Yi
Aging and Disease    DOI: 10.14336/AD.2016.0620
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