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ISSN 2152-5250
Since 2010
2016 impact factor: 4.648
5 year impact factor: 4.1
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Early edition
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A "Early edition" manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides "Early edition" as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the "Early edition" Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these "Early edition" manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program
Ilia Stambler, Kunlin Jin, Stephanie Lederman, Nir Barzilai, Olshansky S. Jay, Emem Omokaro, Jane Barratt, Vladimir N. Anisimov, Suresh Rattan, Shaohua Yang, Michael Forster, Julie Byles
Aging and Disease    DOI: 10.14336/AD.2017.1120
The Effect of Aquaporin-4 Knockout on Interstitial Fluid Flow and the Structure of the Extracellular Space in the Deep Brain
Teng Ze,Wang Aibo,Wang Peng,Wang Rui,Wang Wei,Han Hongbin
Aging and Disease    DOI: 10.14336/AD.2017.1115
SDF-1/CXCR7 Chemokine Signaling is Induced in the Peri-Infarct Regions in Patients with Ischemic Stroke
Zhang Yu,Zhang Hongxia,Lin Siyang,Chen Xudong,Yao Yu,Mao XiaoOu,Shao Bei,Zhuge Qichuan,Jin Kunlin
Aging and Disease    DOI: 10.14336/AD.2017.1112
The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson’s Disease
Zhao Yong-Fei,Qiong-Zhang,Zhang Jian-Feng,Lou Zhi-Yin,Zu Hen-Bing,Wang Zi-Gao,Zeng Wei-Cheng,Kai-Yao,Xiao Bao-Guo
Aging and Disease    DOI: 10.14336/AD.2017.1028
Effect of Rhythmic Auditory Cueing on Aging Gait: A Systematic Review and Meta-Analysis
Shashank Ghai, Ishan Ghai, Alfred O. Effenberg
Aging and Disease    DOI: 10.14336/AD.2017.1031
NLRC3: A Novel Noninvasive Biomarker for Pulmonary Hypertension Diagnosis
Zha Li-huang,Zhou Jun,Li Tang-zhiming,Luo Hui,He Jing-ni,Zhao Lin,Yu Zai-xin
Aging and Disease    DOI: 10.14336/AD.2017.1102
N-acetylcysteine Treatment Reduces Age-related Hearing Loss and Memory Impairment in the Senescence-Accelerated Prone 8 (SAMP8) Mouse Model
Marie Aurore,Meunier Johann,Brun Emilie,Malmstrom Susanna,Baudoux Veronique,Flaszka Elodie,Naert Gaëlle,Roman François,Cosnier-Pucheu Sylvie,Gonzalez-Gonzalez Sergio
Aging and Disease    DOI: 10.14336/AD.2017.0930
Alteration of Copper Fluxes in Brain Aging: A Longitudinal Study in Rodent Using 64CuCl2-PET/CT
Fangyu Peng, Fang Xie, Otto Muzik
Aging and Disease    DOI: 10.14336/AD.2017.1025
Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer’s Disease
H. Eckert Schamim,Gaca Janett,Kolesova Nathalie,Friedland Kristina,P. Eckert Gunter,E. Muller Walter
Aging and Disease    DOI: 10.14336/AD.2017.1014
Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages)
Yang Yao-Chih,Tsai Cheng-Yen,Chen Chien-Lin,Kuo Chia-Hua,Hou Chien-Wen,Cheng Shi-Yann,Aneja Ritu,Huang Chih-Yang,Kuo Wei-Wen
Aging and Disease    DOI: 10.14336/AD.2017.0924
Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson’s Disease
Federica De Lazzari, Luigi Bubacco, Alexander J Whitworth, Marco Bisaglia
Aging and Disease    DOI: 10.14336/AD.2017.1018
Removal of Chylomicron Remnants from the Bloodstream is Delayed in Aged Subjects
Carmen G. Vinagre, Fatima R. Freitas, Carlos H. de Mesquita, Juliana C Vinagre, Ana Carolina Mariani, Roberto Kalil-Filho, Raul C. Maranh?o
Aging and Disease    DOI: 10.14336/AD.2017.1003
Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation
Can Zhang, Nicole R. Brandon, Kerryann Koper, Pei Tang, Yan Xu, Huanyu Dou
Aging and Disease    DOI: 10.14336/AD.2017.0926
The Prevalence of Mild Cognitive Impairment in China: A Systematic Review
Xue Jiang,Li Jiarui,Liang Jiaming,Xie Luokun,Chen Shulin
Aging and Disease    DOI: 10.14336/AD.2017.0928
Glibenclamide Enhances the Therapeutic Benefits of Early Hypothermia after Severe Stroke in Rats
Zhu Shuzhen,Gao Xiaoya,Huang Kaibin,Gu Yong,Hu Yafang,Wu Yongming,Ji Zhong,Wang Qing,Pan Suyue
Aging and Disease    DOI: 10.14336/AD.2017.0927
Effect of Aging and Glucagon-like Peptide 2 on Intestinal Microbiota in SD Rats
Wu Jiayu,Ren Weiying,Li Li,Luo Man,Xu Kan,Shen Jiping,Wang Jia,Chang Guilin,Lu Yi,Qi Yiming,Xu Binger,He Yuting,Hu Yu
Aging and Disease    DOI: 10.14336/AD.2017.1001
Gait Analyses in Mice: Effects of Age and Glutathione Deficiency
Thomas Mock J.,G. Knight Sherilynn,H. Vann Philip,M. Wong Jessica,L. Davis Delaney,J. Forster Michael,Sumien* Nathalie
Aging and Disease    DOI: 10.14336/AD.2017.0925
The Role of Pulmonary and Systemic Immunosenescence in Acute Lung Injury
Christina Brandenberger, Katharina Maria Kling, Marius Vital, Christian Mühlfeld
Aging and Disease    DOI: 10.14336/AD.2017.0902
The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review
Liang Wei,Huang Xiaobo,Chen Wenqiang
Aging and Disease    DOI: 10.14336/AD.2017.0829
Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer's Disease Involves Nrf2/HO-1 Pathway
Fabiana Morroni, Giulia Sita, Agnese Graziosi, Eleonora Turrini, Carmela Fimognari, Andrea Tarozzi, Patrizia Hrelia
Aging and Disease    DOI: 10.14336/AD.2017.0903
CLARITY for High-resolution Imaging and Quantification of Vasculature in the Whole Mouse Brain
Zhang Lin-Yuan,Lin *Pan,Pan Jiaji,Ma Yuanyuan,Wei Zhenyu,Jiang Lu,Wang Liping,Song Yaying,Wang Yongting,Zhang Zhijun,Jin Kunlin,Wang Qian,Yang Guo-Yuan
Aging and Disease    DOI: 10.14336/AD.2017.0613
Association of ApoE Genetic Polymorphism and Type 2 Diabetes with Cognition in Non-Demented Aging Chinese Adults: A Community Based Cross-Sectional Study
Zhen Jie,Lin Tong,Huang Xiaochen,Zhang Huiqiang,Dong Shengqi,Wu Yifan,Song Linlin,Xiao Rong,Yuan Linhong
Aging and Disease    DOI: 10.14336/AD.2017.0715
Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson’s Disease
Zhang Li,Hao Junwei,Zheng Yan,Su Ruijun,Liao Yajin,Gong Xiaoli
Aging and Disease    DOI: 10.14336/AD.2017.0831
BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders
Ting Shen, Yuyi You, Chitra Joseph, Mehdi Mirzaei, Alexander Klistorner, Stuart L. Graham, Vivek Gupta
Aging and Disease    DOI: 10.14336/AD.2017.0717
Synergistically Induced Hypothermia and Enhanced Neuroprotection by Pharmacological and Physical Approaches in Stroke
Zhang Jun,Liu Kaiyin,Elmadhoun Omar,Ji Xunming,Duan Yunxia,Shi Jingfei
Aging and Disease    DOI: 10.14336/AD.2017.08167
Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes
Tang Feng,Pan Meng-Hao,Lu Yujie,Wan Xiang,Zhang Yu,Sun Shao-Chen
Aging and Disease    DOI: 10.14336/AD.2017.0901
Voxel-based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) on 3-tesla Normal Database: Diagnostic Accuracy in Two Independent Cohorts with Early Alzheimer’s Disease
Sone Daichi,Imabayashi Etsuko,Maikusa Norihide,Ogawa Masayo,Sato Noriko,Matsuda Hiroshi,Disease Neuroimaging Initiative Japanese-Alzheimer’s
Aging and Disease    DOI: 10.14336/AD.2017.0818
Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
Liu Ping,Zhao Haiping,Luo Yumin
Aging and Disease    DOI: 10.14336/AD.2017.0816
Repetitive Element DNA Methylation is Associated with Menopausal Age
Lu Sha,Niu Zheng,Chen Yueming,Tu Qiaofeng,Zhang Yue,Chen Wenli,Tong Wenjuan,Zhang Zhifen
Aging and Disease    DOI: 10.14336/AD.2017.0810
Anserine/Carnosine Supplementation Preserves Blood Flow in the Prefrontal Brain of Elderly People Carrying APOE e4
Ding Qiong,Tanigawa Kitora,Kaneko Jun,Totsuka Mamoru,Katakura Yoshinori,Imabayashi Etsuko,Matsuda Hiroshi,Hisatsune Tatsuhiro
Aging and Disease    DOI: 10.14336/AD.2017.0809
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