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ISSN 2152-5250
Since 2010
2016 impact factor: 4.648
5 year impact factor: 4.1
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Early edition
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A "Early edition" manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides "Early edition" as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the "Early edition" Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these "Early edition" manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity
Yaiza Potes, Zulema Perez-Martinez, Juan C. Bermejo-Millo Juan, Adrian Rubio-Gonzalez, Maria Fernandez-Fernandez, Manuel Bermudez, et al.
Aging and Disease    DOI: 10.14336/AD.2018.0430
Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?
Michael G. Flynn, Melissa M. Markofski, Andres E. Carrillo
Aging and Disease    DOI: 10.14336/AD.2018.0326
Traditional Oriental Medicines and Alzheimer’s Disease
Seong Gak Jeon, Eun Ji Song, Dongje Lee, Junyong Park, Yunkwon Nam, Jin-il Kim, Minho Moon
Aging and Disease    DOI: 10.14336/AD.2018.0328
Quantitative Evaluation of Gait Disturbance on an Instrumented Timed Up-and-go Test
Shigeki Yamada, Yukihiko Aoyagi, Kazuo Yamamoto, Masatsune Ishikawa
Aging and Disease    DOI: 10.14336/AD.2018.0426
Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease
Christopher Bi, Stephanie Bi, Bin Li
Aging and Disease    DOI: 10.14336/AD.2018.0425
Prospective Study of Glycated Hemoglobin and Trajectories of Depressive Symptoms: The China Health and Retirement Longitudinal Study
Haibin Li, Anxin Wang, Wei Feng, Deqiang Zheng, Qi Gao, Lixin Tao, Jin Guo, Xiaonan Wang, Xia Li, Wei Wang, Xiuhua Guo
Aging and Disease    DOI: 10.14336/AD.2018.0410
MicroRNAs and the Genetic Nexus of Brain Aging, Neuroinflammation, Neurodegeneration, and Brain Trauma
Saumyendra N. Sarkar, Ashley E. Russell, Elizabeth B. Engler-Chiurazzi, Keyana N. Porter, James W. Simpkins
Aging and Disease    DOI: 10.14336/AD.2018.0409
Influence of Environment and Lifestyle on Incidence and Progress of Amyotrophic Lateral Sclerosis in A German ALS Population
Korner Sonja, Kammeyer Johanna, Zapf Antonia, Kuzma-Kozakiewicz Magdalena, Piotrkiewicz Maria, Kuraszkiewicz Bo , enna, Goszczynska Hanna, Gromicho Marta, Grosskreutz Julian, M. Andersen Peter, de Carvalho Mamede, Petri Susanne
Aging and Disease    DOI: 10.14336/AD.2018.0327
Age-Related Changes in Femoral Head Trabecular Microarchitecture
Charlene Greenwood, John Clement, Anthony Dicken, Paul Evans, Iain Lyburn, Richard M. Martin, Nick Stone, Peter Zioupos, Keith Rogers
Aging and Disease    DOI: 10.14336/AD.2018.0124
Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept
Young Chung Hae, Hyun Kim Dae, Kyeong Lee Eun, Wung Chung Ki, Chung Sangwoon, Lee Bonggi, Y. Seo Arnold, Heun Chung Jae, Suk Jung Young, Im Eunok, Lee Jaewon, Deuk Kim Nam, Ja Choi Yeon, Soon Im Dong, Pal Yu Byung
Aging and Disease    DOI: 10.14336/AD.2018.0324
Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population
Geraldo Rubens Ramos Freitas, Maria da Luz Fernandes, Fabiana Agena, Omar Jaluul, Sergio Colenci Silva, Francine Brambate Carvalhinho Lemos, Veronica Coelho, Elias David-Neto, Nelson Zocoler Galante
Aging and Disease    DOI: 10.14336/AD.2018.0318
Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia
Yuxiao Liao, Zhao Peng, Liangkai Chen, Yan Zhang, Qian Cheng, Andreas K. Nussler, Wei Bao, Liegang Liu, Wei Yang
Aging and Disease    DOI: 10.14336/AD.2018.0325
miRNA-10b Reciprocally Stimulates Osteogenesis and Inhibits Adipogenesis Partly Through the TGF-β/SMAD2 Signaling Pathway
Hongling Li, Junfen Fan, Linyuan Fan, Tangping Li, Yanlei Yang, Haoying Xu, Luchan Deng, Jing Li, Tao Li, Xisheng Weng, Shihua Wang, Chunhua Robert Zhao
Aging and Disease    DOI: 10.14336/AD.2018.0214
Relationship between Hypothyroidism and Endometrial Cancer
Wang Yiqin,Zhou Rong,Wang Jianliu
Aging and Disease    DOI: 10.14336/AD.2018.0224
Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection
Manuel Scimeca, Federica Centofanti, Monica Celi, Elena Gasbarra, Giuseppe Novelli, Annalisa Botta, Umberto Tarantino
Aging and Disease    DOI: 10.14336/AD.2018.0215
Increased Inflammatory Response in Old Mice is Associated with More Severe Neuronal Injury at the Acute Stage of Ischemic Stroke
Shen Fanxia,Jiang Lidan,Han Frank,Degos Vincent,Chen Shengdi,Su Hua
Aging and Disease    DOI: 10.14336/AD.2018.0205
DRAM is Involved in Hypoxia/Ischemia-Induced Autophagic Apoptosis in Hepatocytes
Xu Jianji,Zang Yunjin,Liu Dongjie,Yang Tongwang,Wang Jieling,Wang Yanjun,Liu Xiaoni,Chen Dexi
Aging and Disease    DOI: 10.14336/AD.2018.0210
A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder
Yu-Wen Huang, Ming-Fu Chiang, Che-Sheng Ho, Pi-Lien Hung, Mei-Hsin Hsu, Tsung-Han Lee, Julie Lichieh Chu, Hsuan Liu, Petrus Tang, Victor Wailap Ng, Dar-Shong Lin
Aging and Disease    DOI: 10.14336/AD.2018.0222
Intracranial Atherosclerosis Burden and Stroke Recurrence for Symptomatic Intracranial Artery Stenosis (sICAS)
Sun Ping, Liu Liping, Pan Yuesong, Wang Xianwei, Mi Donghua, Pu Yuehua, Liu Xin, Duan Wanying, Yan Hongyi, Wang Chunxue, Zhao Xingquan, Wang Yilong, Wang Yongjun, on behalf of CICAS investigators
Aging and Disease    DOI: 10.14336/AD.2018.0301
Omi/HtrA2 Participates in Age-Related Autophagic Deficiency in Rat Liver
Xu Jiahui,Jiao Kun,Liu Xin,Sun Qi,Wang Ke,Xu Haibo,Zhang Shangyue,Wu Ye,Wu Linguo,Liu Dan,Wang Wen,Liu Huirong
Aging and Disease    DOI: 10.14336/AD.2018.0221
Kidney Disease in Elderly: Importance of Collaboration between Geriatrics and Nephrology
Faheemuddin Azher Ahmed
Aging and Disease    DOI: 10.14336/AD.2018.0223
Splenectomy Fails to Provide Long-Term Protection Against Ischemic Stroke
Yuanyuan Ran, Zongjian Liu, Shuo Huang, Jiamei Shen, Fengwu Li, Wenxiu Zhang, Chen Chen, Xiaokun Geng, Zhili Ji, Huishan Du, Xiaoming Hu
Aging and Disease    DOI: 10.14336/AD.2018.0130
Chronic Kidney Disease Is Linked to Carotid Nodular Calcification, An Unstable Plaque Not Correlated to Inflammation
Cardellini Marina, Rovella Valentina, Scimeca Manuel, Anemona Lucia, Bischetti Simone, Casella Sara, Saggini Andrea, Bonanno Elena, Ballanti Marta, Davato Francesca, Menghini Rossella, Ippoliti Arnaldo, Santeusanio Giuseppe, Di Daniele Nicola, Federici Massimo, Mauriello Alessandro
Aging and Disease    DOI: 10.14336/AD.2018.0117
Glycation Damage: A Possible Hub for Major Pathophysiological Disorders and Aging
Maxime Fournet, Frederic Bontee, Alexis Desmouliere
Aging and Disease    DOI: 10.14336/AD.2017.1121
REST rs3796529 Genotype and Rate of Functional Deterioration in Alzheimer's Disease
Poyin Huang, Cheng-Sheng Chen, Yuan-Han Yang, Mei-Chuan Chou, Ya-Hsuan Chang, Chiou-Lian Lai, Hsuan-Yu Chen, Ching-Kuan Liu
Aging and Disease    DOI: 10.14336/AD.2018.0116
LMNA-mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy
Sui Tingting,Liu Di,Liu Tingjun,Deng Jichao,Chen Mao,Xu Yuanyuan,Song Yuning,Ouyang Hongsheng,Lai Liangxue,Li Zhanjun
Aging and Disease    DOI: 10.14336/AD.2018.0209
Stronger Association between Insomnia Symptoms and Shorter Telomere Length in Old HIV-infected Patients Compared with Uninfected Individuals
Yingying Ding, Haijiang Lin, Sujuan Zhou, Keran Wang, Lingling Li, Yucheng Zhang, Yuan Yao, Meiyang Gao, Xing Liu, Na He
Aging and Disease    DOI: 10.14336/AD.2018.0204
Relationship Between Cortical Thickness and Neuropsychological Performance in Normal Older Adults and Those with Mild Cognitive Impairment
Calvin Pak-Wing Cheng, Sheung-Tak Cheng, Cindy Woon-Chi Tam, Wai-Chi Chan, Winnie Chiu-Wing Chu, Linda Chiu-Wa Lam
Aging and Disease    DOI: 10.14336/AD.2018.0125
Is Dementia More Fatal Than Previously Estimated? A Population-based Prospective Cohort Study
Jong Bin Bae, Ji Won Han, Kyung Phil Kwak, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Tae Kim Kim, Seung-Ho Ryu, Seok Woo Moon, Joon Hyuk Park, Jong Chul Youn, Dong Yong Lee, et al.
Aging and Disease    DOI: 10.14336/AD.2018.0123
Molecular Bases of Alzheimer’s Disease and Neurodegeneration: The Role of Neuroglia
Antonina Luca , Carmela Calandra, Maria Luca
Aging and Disease    DOI: 10.14336/AD.2018.0201
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