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Just Accepted
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A “Just Accepted” manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides “Just Accepted” as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these “Just Accepted” manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?
Sankha Shubhra Chakrabarti, Upinder Kaur, Anindita Banerjee, Upasana Ganguly, Tuhina Banerjee, Sarama Saha, Gaurav Parashar, Suvarna Prasad, Suddhachitta Chakrabarti, Amit Mittal, Bimal Kumar Agrawal, Ravindra Kumar Rawal, Robert Chunhua Zhao, Indrajeet Singh Gambhir, Rahul Khanna, Ashok K Shetty, Kunlin Jin, Sasanka Chakrabarti
Aging and disease    DOI: 10.14336/AD.2020.0402
Accepted: 03 April 2020

Mesenchymal Stem Cells for Coronavirus (COVID-19)-Induced Pneumonia: Revisiting the Paracrine Hypothesis with New Hopes?
Selçuk Öztürk, Ayşe Eser Elçin, Yaşar Murat Elçin
Aging and disease    DOI: 10.14336/AD.2020.0403
Accepted: 03 April 2020

Rationale and Methodology of The PopulatION HEalth and Eye Disease PRofile in Elderly Singaporeans Study [PIONEER]
Preeti Gupta, Ryan Eyn Kidd Man, Eva K. Fenwick, Amudha Aravindhan, Alfred TL Gan, Sahil Thakur, Bao Lin Pauline Soh, Joanne M Wood, Alex A Black, Angelique Chan, David Ng, Teoh Khim Hean, Edwin Goh, Chong Foong-Fong Mary, Jenny Loo, Ciaran Gerard Forde, Charumathi Sabanayagam, Ching-Yu Cheng, Tien Yin Wong, Ecosse L. Lamoureux
Aging and disease    DOI: 10.14336/AD.2020.0206
Accepted: 02 April 2020

Ischemic Conditioning Ameliorated Hypertension and Vascular Remodeling of Spontaneously Hypertensive Rat via Inflammatory Regulation
Yu Gao, Changhong Ren, Xiaohua Li, Wantong Yu, Sijie Li, Haiyan Li, Yan Wang, Dong Li, Ming Ren, Xunming Ji
Aging and disease    DOI: 10.14336/AD.2020.0320
Accepted: 02 April 2020

Rodent Models of Amyloid-Beta Feature of Alzheimer’s Disease: Development and Potential Treatment Implications
Chi Him Poon, Yingyi Wang, Man-Lung Fung, Chengfei Zhang, Lee Wei Lim
Aging and disease    DOI: 10.14336/AD.2019.1026
Accepted: 31 March 2020

Relationships between Mitochondrial Dysfunction and Neurotransmission Failure in Alzheimer’s Disease
Kan Yin Wong, Jaydeep Roy, Man Lung Fung, Boon Chin Heng, Chengfei Zhang, Lee Wei Lim
Aging and disease    DOI: 10.14336/AD.2019.1125
Accepted: 31 March 2020

Roles of the MYST Family in the Pathogenesis of Alzheimer’s Disease via Histone or Non-histone Acetylation
Yuhong Li, Hui Huang, Man Zhu, Hua Bai, Xiaowei Huang
Aging and disease    DOI: 10.14336/AD.2020.0329
Accepted: 30 March 2020

Intra-arterial Cold Saline Infusion in Stroke: Historical Evolution and Future Prospects
Longfei Wu, Mitchell Huber, Di Wu, Jian Chen, Ming Li, Yuchuan Ding, Xunming Ji
Aging and disease    DOI: 10.14336/AD.2020.0325
Accepted: 28 March 2020

Serine and Metabolism Regulation: A Novel Mechanism in Antitumor Immunity and Senescence
Qi Wu, Xinyue Chen, Juanjuan Li, Shengrong Sun
Aging and disease    DOI: 10.14336/AD.2020.0314
Accepted: 25 March 2020

The Mechanism of Downregulated Interstitial Fluid Drainage Following Neuronal Excitation
Yuanyuan Li, Hongbin Han, Kuangyu Shi, Dehua Cui, Jun Yang, Ian Leigh Alberts, Lan Yuan, Guomei Zhao, Rui Wang, Xianjie Cai, Ze Teng
Aging and disease    DOI: 10.14336/AD.2020.0224
Accepted: 21 March 2020

TGF-β Signaling: A Therapeutic Target to Reinstate Regenerative Plasticity in Vascular Dementia?
Mahesh Kandasamy, Muthuswamy Anusuyadevi, Kiera M Aigner, Michael S Unger, Kathrin M Kniewallner, Diana M Bessa de Sousa, Barbara Altendorfer, Heike Mrowetz, Ulrich Bogdahn, Ludwig Aigner
Aging and disease    DOI: 10.14336/AD.2020.0222
Accepted: 18 March 2020

The Application of Artificial Intelligence in the Genetic Study of Alzheimer’s Disease
Rohan Mishra, Bin Li
Aging and disease    DOI: 10.14336/AD.2020.0312
Accepted: 16 March 2020

Circular RNAs: Promising Biomarkers for Age-related Diseases
Yan-hong Pan, Wei-peng Wu, Xing-dong Xiong
Aging and disease    DOI: 10.14336/AD.2020.0309
Accepted: 13 March 2020

Oxidative Stress at the Crossroads of Aging, Stroke and Depression
Anwen Shao, Danfeng Lin, Lingling Wang, Sheng Tu, Cameron Lenahan, Jianmin Zhang
Aging and disease    DOI: 10.14336/AD.2020.0225
Accepted: 01 March 2020

Prevalence of High Jugular Bulb across Different Stages of Adulthood in A Chinese Population
Jingjing Wang, Yanmei Feng, Hui Wang, Chunyan Li, Yaqin Wu, Haibo Shi, Zhengnong Chen, Shankai Yin
Aging and disease    DOI: 10.14336/AD.2020.0215
Accepted: 17 February 2020

Alteration of Metabolic Profile and Potential Biomarkers in the Plasma of Alzheimer’s Disease
Yaping Shao, Yang Ouyang, Tianbai Li, Xinyao Liu, Xiaojiao Xu, Song Li, Guowang Xu, Weidong Le
Aging and disease    DOI: 10.14336/AD.2020.0217
Accepted: 17 February 2020

The Critical Role of SIRT1 in Parkinson’s Disease: Mechanism and Therapeutic Considerations
Xuan Li, Ya Feng, Xi-Xi Wang, Daniel Truong, Yun-Cheng Wu
Aging and disease    DOI: 10.14336/AD.2020.0216
Accepted: 16 February 2020

A Perspective on Roles Played by Immunosenescence in the Pathobiology of Alzheimer's Disease
Yan Zhao, Jun-Kun Zhan, Youshuo Liu
Aging and disease    DOI: 10.14336/AD.2020.0205
Accepted: 13 February 2020

Premature CD4+ T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary Syndrome
Ming Cao, Lei Ruan, Yi Huang, Jinli Wang, Jinhua Yan, Yu Sang, Shanshan Li, Guan Wang, Xiaofen Wu
Aging and disease    DOI: 10.14336/AD.2020.0203
Accepted: 12 February 2020

Reparative Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor in Aged APP/PS1 Mice
Xingzhi Guo, Yanying Liu, David Morgan, Li-Ru Zhao
Aging and disease    DOI: 10.14336/AD.2020.0201
Accepted: 11 February 2020

Emotional Lability at Disease Onset Is an Independent Prognostic Factor of Faster Disease Progression in Amyotrophic Lateral Sclerosis
Krzysztof Barć, Katarzyna Szacka, Krzysztof Nieporęcki, Mamede de Carvalho, Marta Gromicho, Julian Grosskreutz, Susanne Petri, Annekathrin Rödiger, Robert Steinbach, Hilmi Uysal, Magdalena Kuźma-Kozakiewicz
Aging and disease    DOI: 10.14336/AD.2019.1120
Accepted: 04 February 2020

Serum Occludin as a Biomarker to Predict the Severity of Acute Ischemic Stroke, Hemorrhagic Transformation, and Patient Prognosis
Weili Li, Zhifeng Qi, Huining Kang, Xuzhen Qin, Haiqing Song, Xueqin Sui, Yi Ren, Xunming Ji, Qingfeng Ma, Ke Jian Liu
Aging and disease    DOI: 10.14336/AD.2020.0119
Accepted: 04 February 2020

Molecular Aging Markers in Patients with Klinefelter Syndrome
Eva Pohl, Sina Muschal, Sabine Kliesch, Michael Zitzmann, Julia Rohayem, Jörg Gromoll, Sandra Laurentino
Aging and disease    DOI: 10.14336/AD.2019.0801
Accepted: 27 January 2020

Targeting AMP-Activated Protein Kinase in Aging-Related Cardiovascular Diseases
Tian Li, Nan Mu, Yue Yin, Lu Yu, Heng Ma
Aging and disease    DOI: 10.14336/AD.2019.0901
Accepted: 27 January 2020

Pathological Mechanisms and Potential Therapeutic Targets of Pulmonary Arterial Hypertension: A Review
Ying Xiao, Pei-Pei Chen, Rui-Lin Zhou, Yang Zhang, Zhuang Tian, Shu-Yang Zhang
Aging and disease    DOI: 10.14336/AD.2020.0111
Accepted: 16 January 2020

A Glimmer of Hope: Maintain Mitochondrial Homeostasis to Mitigate Alzheimer’s Disease
Wenbo Li, Ling Kui, Tsirukis Demetrios, Xun Gong, Min Tang
Aging and disease    DOI: 10.14336/AD.2020.0105
Accepted: 10 January 2020

Prebiotics Regulation of Intestinal Microbiota Attenuates Cognitive Dysfunction Induced by Surgery Stimulation in APP/PS1 Mice
Dengyang Han, Zhengqian Li, Taotao Liu, Ning Yang, Yue Li, Jindan He, Min Qian, Zhongshen Kuang, Wen Zhang, Cheng Ni, Xiangyang Guo
Aging and disease    DOI: 10.14336/AD.2020.0106
Accepted: 08 January 2020

Age-related CCL12 Aggravates Intracerebral Hemorrhage-induced Brain Injury via Recruitment of Macrophages and T Lymphocytes
Jiacheng Huang, Guoqiang Yang, Xiaoyi Xiong, Maolin Wang, Junjie Yuan, Qing Zhang, Changxiong Gong, Zhongming Qiu, Zhaoyou Meng, Rui Xu, Qiong Chen, Ru Chen, Lexing Xie, Qi Xie, Wenjie Zi, Guohui Jiang, Yu Zhou, Qingwu Yang
Aging and disease    DOI: 10.14336/AD.2019.1229
Accepted: 07 January 2020

Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage
Li Tan, Thomas C. Register, Raghunatha R. Yammani
Aging and disease    DOI: 10.14336/AD.2019.1130
Accepted: 07 January 2020

Chondroprotective Effects of Combination Therapy of Acupotomy and Human Adipose Mesenchymal Stem Cells in Knee Osteoarthritis Rabbits via the GSK3β-Cyclin D1-CDK4/CDK6 Signaling Pathway
Xingyan An, Tong Wang, Wei Zhang, Hongliang Yu, Robert Chunhua Zhao, Yan Guo, Chunjiu Wang, Luxue Qin, Changqing Guo
Aging and disease    DOI: 10.14336/AD.2019.1104
Accepted: 04 January 2020
Online available: 04 January 2020

Infrapatellar Fat Pad and Knee Osteoarthritis
Ni Zeng, Zhi-Peng Yan, Xin-Yuan Chen, Guo-Xin Ni
Aging and disease    DOI: 10.14336/AD.2019.1116
Accepted: 06 December 2019

An updated review of the epigenetic mechanism underlying the pathogenesis of age-related macular degeneration
Xiaohua Li, Shikun He, Mingwei Zhao
Aging and disease    DOI: 10.14336/AD.2019.1126
Accepted: 05 December 2019

Pyroptosis Plays a Role in Osteoarthritis
Senbo An, Huiyu Hu, Yusheng Li, Yihe Hu
Aging and disease    DOI: 10.14336/AD.2019.1127
Accepted: 30 November 2019

Influence of Frailty on Outcome in Older Patients Undergoing Non-Cardiac Surgery - A Systematic Review and Meta-Analysis
Elke K.M. Tjeertes, Joris M.K. van Fessem, Francesco U.S. Mattace-Raso, Anton G.M. Hoofwijk, Robert Jan Stolker, Sanne E. Hoeks
Aging and disease    DOI: 10.14336/AD.2019.1024
Accepted: 26 November 2019

Management of The Elderly Cancer Patients Complexity: The Radiation Oncology Potential
Giuseppe Colloca, Luca Tagliaferri, Beatrice Di Capua, Maria Antonietta Gambacorta, Vito Lanzotti, Andrea Bellieni, Silvio Monfardini, Lodovico Balducci, Roberto Bernabei, William C. Cho, Vincenzo Valentini
Aging and disease    DOI: 10.14336/AD.2019.0616
Accepted: 19 November 2019

Trends in LDL-C and Non-HDL-C Levels with Age
Peng Zhang, Qian Su, Xiaomiao Ye, Ping Guan, Chengjun Chen, Yanwen Hang, Jian Dong, Zhongjie Xu, Wei Hu
Aging and disease    DOI: 10.14336/AD.2019.1025
Accepted: 19 November 2019

Six Visual Rating Scales as A Biomarker for Monitoring Atrophied Brain Volume in Parkinson's Disease
Yu Lin, Ying Fu, Yi-Fang Zeng, Jian-Ping Hu, Xiao-Zhen Lin, Nai-Qing Cai, Qiang Weng, Yi-Jing Zhao, Yi Lin, Dai-Rong Cao, Ning Wang
Aging and disease    DOI: 10.14336/AD.2019.1103
Accepted: 12 November 2019

The Significance of 8-oxoGsn in Age-Related Diseases
Xinmu Zhang, Lin Li
Aging and disease    DOI: 10.14336/AD.2019.1021
Accepted: 07 November 2019

A Novel Individual-based Determination of Postoperative Cognitive Dysfunction in Mice
Jing Zhong, Jun Li, Changhong Miao, Zhiyi Zuo
Aging and disease    DOI: 10.14336/AD.2019.1029
Accepted: 31 October 2019

Practical Approaches to Treat ED in PDE5i Nonresponders
Zhonglin Cai, Xiaoqing Song, Jianzhong Zhang, Bin Yang, Hongjun Li
Aging and disease    DOI: 10.14336/AD.2019.1028
Accepted: 29 October 2019

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