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Just Accepted
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A “Just Accepted” manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides “Just Accepted” as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these “Just Accepted” manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction
Hyun-Doo Song, Sang Nam Kim, Abhirup Saha, Sang-Yeop Ahn, Seun Akindehin, Yeonho Son, Yoon Keun Cho, MinSu Kim, Ji-Hyun Park, Young-Suk Jung, Yun-Hee Lee
Aging and disease    DOI: 10.14336/AD.2019.0810
Accepted: 14 August 2019

Renoprotective Effect of a Dipeptidyl Peptidase-4 Inhibitor on Aging Mice
Tae H. Ban, Eun N. Kim, Min Y. Kim, Ji H. Lim, Jong H. Lee, Hyung D. Kim, Hye E. Yoon, Cheol W. Park, Bum S. Choi
Aging and disease    DOI: 10.14336/AD.2019.0620
Accepted: 09 August 2019

A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology
Dinesh Upadhya, Maheedhar Kodali, Daniel Gitai, Olagide W. Castro, Gabriele Zanirati, Raghavendra Upadhya, Sahithi Attaluri, Eeshika Mitra, Bing Shuai, Bharathi Hattiangady, Ashok K. Shetty
Aging and disease    DOI: 10.14336/AD.2019.0720
Accepted: 07 August 2019

Lactulose Suppresses Osteoclastogenesis and Ameliorates Estrogen Deficiency-Induced Bone Loss in Mice
Xiao Chen, Zheng Zhang, Yan Hu, Jin Cui, Xin Zhi, Xiaoqun Li, Hao Jiang, Yao Wang, Zhengrong Gu, Zili Qiu, Xin Dong, Yuhong Li, Jiacan Su
Aging and disease    DOI: 10.14336/AD.2019.0613
Accepted: 05 August 2019

The Critical Role of Nurr1 as a Mediator and Therapeutic Target in Alzheimer’s Disease-related Pathogenesis
Seong Gak Jeon, Anji Yoo, Dong Wook Chun, Sang Bum Hong, Hyunju Chung, Jin-il Kim, Minho Moon, Moon Minho
Aging and disease    DOI: 10.14336/AD.2019.0718
Accepted: 01 August 2019
Online available: 02 August 2019

Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients
Janina Tiemann, Thomas Wagner, Olivier M. Vanakker, Matthias van Gils, José-Luis Bueno Cabrera, Bettina Ibold, Isabel Faust, Cornelius Knabbe, Doris Hendig
Aging and disease    DOI: 10.14336/AD.2019.0610
Accepted: 31 July 2019

Macrophages in Noise-Exposed Cochlea: Changes, Regulation and the Potential Role
Weiwei He, Jintao Yu, Yu Sun, Weijia Kong
Aging and disease    DOI: 10.14336/AD.2019.0723
Accepted: 29 July 2019

SRμCT Reveals 3D Microstructural Alterations of the Vascular and Neuronal Network in a Rat Model of Chronic Compressive Thoracic Spinal Cord Injury
Liyuan Jiang, Yong Cao, Zhen Liu, Shuangfei Ni, Jun Liu, Yoon Ha, Zixiang Luo, Chengjun Li, Shaohua Liu, Jingsong Li, Xianzhen Yin, Tianding Wu, Hongbin Lu, Jianzhong Hu
Aging and disease    DOI: 10.14336/AD.2019.0529
Accepted: 26 July 2019

Neuroprotective Effects of Endogenous Secretory Receptor for Advanced Glycation End-products in Brain Ischemia
Yu Shimizu, Ai Harashima, Seiichi Munesue, Masahiro Oishi, Tsuyoshi Hattori, Osamu Hori, Yasuko Kitao, Hiroshi Yamamoto, Nontaphat Leerach, Mitsutoshi Nakada, Yasuhiko Yamamoto, Yasuhiko Hayashi
Aging and disease    DOI: 10.14336/AD.2019.0715
Accepted: 26 July 2019

Role of Mitophagy in Cardiovascular Disease
Yibo Yang, Tianyi Li, Zhibo Li, Ning Liu, Youyou Yan, Bin Liu*
Aging and disease    DOI: 10.14336/AD.2019.0518
Accepted: 22 July 2019

The Paradoxical Effect of Deep Brain Stimulation on Memory
Shawn Zheng Kai Tan, Man-Lung Fung, Junhao Koh, Ying-Shing Chan, Lee Wei Lim*
Aging and disease    DOI: 10.14336/AD.2019.0511
Accepted: 21 July 2019

Divergent Effect of Tacalcitol (PRI-2191) on Th17 Cells in 4T1 Tumor Bearing Young and Old Ovariectomized Mice
Agata Pawlik, Artur Anisiewicz, Beata Filip-Psurska, Dagmara Klopotowska, Magdalena Maciejewska, Andrzej Mazur, Joanna Wietrzyk
Aging and disease    DOI: 10.14336/AD.2019.0618
Accepted: 21 July 2019

Exogenous H2S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts
Miao Yu, Haining Du, Bingzhu Wang, Jian Chen, Fangping Lu, Shuo Peng, Yu Sun, Ning Liu, Xiaojiao Sun, Shiyun Dong, Yajun Zhao, Yan Wang, Dechao Zhao, Fanghao Lu, Weihua Zhang
Aging and disease    DOI: 10.14336/AD.2019.0530
Accepted: 21 July 2019

Impaired Frontoparietal Connectivity in Traumatic Individuals with Disorders of Consciousness: A Dynamic Brain Network Analysis
Min Wu, Fali Li, Yuehao Wu, Tieying Zhang, Jian Gao, Peng Xu, Benyan Luo
Aging and disease    DOI: 10.14336/AD.2019.0606
Accepted: 21 July 2019

Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice
Yu Sun, Fanghao Lu, Xiangjing Yu, Bingzhu Wang, Jian Chen, Fangping Lu, Shuo Peng, Xiaojiao Sun, Miao Yu, He Chen, Yan Wang, Linxue Zhang, Ning Liu, Haining Du, Dechao Zhao, Weihua Zhang
Aging and disease    DOI: 10.14336/AD.2019.0524
Accepted: 21 July 2019

T1-weighted MRI-driven Brain Age Estimation in Alzheimer’s Disease and Parkinson’s Disease
Iman Beheshti, Shiwangi Mishra, Daichi Sone, Pritee Khanna, Hiroshi Matsuda, for the Alzheimer's Disease Neuroimaging Initiative, Parkinson’s Progression Markers Initiative
Aging and disease    DOI: 10.14336/AD.2019.0617
Accepted: 21 July 2019

Disease Progression-Dependent Expression of CD200R1 and CX3CR1 in Mouse Models of Parkinson’s Disease
Le Wang, Yang Liu, Shuxin Yan, Tianshu Du, Xia Fu, Xiaoli Gong, Xinyu Zhou, Ting Zhang, Xiaomin Wang
Aging and disease    DOI: 10.14336/AD.2019.0615
Accepted: 05 July 2019

Association between Loss of Sleep-specific Waves and Age, Sleep Efficiency, Body Mass Index, and Apnea-Hypopnea Index in Human N3 Sleep
Weiguang Li, Ying Duan, Jiaqing Yan, He Gao, Xiaoli Li
Aging and disease    DOI: 10.14336/AD.2019.0420
Accepted: 02 July 2019

A Review of Exercise as Medicine in Cardiovascular Disease: Pathology and Mechanism
Piotr Gronek, Dariusz Wielinski, Piotr Cyganski, Andrzej Rynkiewicz, Adam Zając, Adam Maszczyk, Joanna Gronek, Robert Podstawski, Wojciech Czarny, Stefan Balko, Cain CT. Clark, Roman Celka
Aging and disease    DOI: 10.14336/AD.2019.0516
Accepted: 02 July 2019

Gut Microbiome and Osteoporosis
Kai Ding, Fei Hua, Wenge Ding
Aging and disease    DOI: 10.14336/AD.2019.0523
Accepted: 14 June 2019

Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice
Chun-Sheng Yang, Ai Guo, Yulin Li, Kaibin Shi, Fu-Dong Shi, Minshu Li
Aging and disease    DOI: 10.14336/AD.2019.0608
Accepted: 13 June 2019

Remote Ischemic Conditioning Improves Attention Network Function and Blood Oxygen Levels in Unacclimatized Adults Exposed to High Altitude
Sijie Li, Cong Han, Karam Asmaro, Shanyi Quan, Ming Li, Changhong Ren, Jun Zhang, Wenbo Zhao, Jiali Xu, Zhiwen Liu, Peng Zhang, Lingling Zhu, Yuchuan Ding, Kai Wang, Xunming Ji, Lian Duan
Aging and disease    DOI: 10.14336/AD.2019.0605
Accepted: 12 June 2019

Aging, Alzheimer’s Disease and Dysfunctional Glycolysis; Similar Effects of Too Much and Too Little
Alan R. Hipkiss
Aging and disease    DOI: 10.14336/AD.2019.0611
Accepted: 12 June 2019

Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction
Ming Dong, Ziyi Yang, Hongcheng Fang, Jiaqing Xiang, Cong Xu, Yanqing Zhou, Qianying Wu, Jie Liu
Aging and disease    DOI: 10.14336/AD.2019.0522
Accepted: 10 June 2019

Caveolin as a Novel Potential Therapeutic Target in Cardiac and Vascular Diseases: A Mini Review
Jinfan Tian, Mohammad Sharif Popal, RongChong Huang, Min Zhang, Xin Zhao, Mingduo Zhang, Xiantao Song
Aging and disease    DOI: 10.14336/AD.2019.09603
Accepted: 09 June 2019

Alteration in the Function and Expression of SLC and ABC Transporters in the Neurovascular Unit in Alzheimer’s Disease and the Clinical Significance
Yongming Jia, Na Wang, Yingbo Zhang, Di Xue, Haoming Lou, Xuewei Liu
Aging and disease    DOI: 10.14336/AD.2019.0519
Accepted: 05 June 2019

Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated Disorders
Sunil S. Adav, Siu Kwan Sze
Aging and disease    DOI: 10.14336/AD.2019.0604
Accepted: 05 June 2019

Pretreatment Geriatric Assessments of Elderly Patients with Glioma: Development and Implications
Yaning Wang, Binghao Zhao, Wanqi Chen, Lei Liu, Wenlin Chen, Lizhou Zhou, Ziren Kong, Congxin Dai, Yu Wang, Wenbin Ma
Aging and disease    DOI: 10.14336/AD.2019.0527
Accepted: 02 June 2019

Ketogenic Diet Ameliorates Cardiac Dysfunction via Balancing Mitochondrial Dynamics and Inhibiting Apoptosis in Type 2 Diabetic Mice
Yongzheng Guo, Cheng Zhang, Minghao Luo, Yuehua You, Qiming Zhai, Feifei Shang, Yong Xia, Suxin Luo
Aging and disease    DOI: 10.14336/AD.2019.0510
Accepted: 01 June 2019
Online available: 01 June 2019

Understanding the Physiological Links Between Physical Frailty and Cognitive Decline
Lina Ma, Piu Chan
Aging and disease    DOI: 10.14336/AD.2019.0521
Accepted: 30 May 2019

Astragalus Polysaccharide Extends Lifespan via Mitigating Endoplasmic Reticulum Stress in the Silkworm, Bombyx mori
Jiangbo Song, Min Chen, Zhiquan Li, Jianfei Zhang, Hai Hu, Xiaoling Tong, Fangyin Dai
Aging and disease    DOI: 10.14336/AD.2019.0515
Accepted: 22 May 2019

Statins Induce a DAF-16/Foxo-dependent Longevity Phenotype via JNK-1 through Mevalonate Depletion in C. elegans
Andreas Jahn, Bo Scherer, Gerhard Fritz, Sebastian Honnen
Aging and disease    DOI: 10.14336/AD.2019.0416
Accepted: 19 May 2019

Angelica Sinensis Polysaccharide Suppresses Epithelial-Mesenchymal Transition and Pulmonary Fibrosis via a DANCR/AUF-1/FOXO3 Regulatory Axis
Weibin Qian, Xinrui Cai, Qiuhai Qian, Dongli Wang, Lei Zhang
Aging and disease    DOI: 10.14336/AD.2019.0512
Accepted: 13 May 2019

Neuropsychological Deficits Chronically Developed after Focal Ischemic Stroke and Beneficial Effects of Pharmacological Hypothermia in the Mouse
Weiwei Zhong, Yan Yuan, Xiaohuan Gu, Samuel In-young Kim, Ryan Chin, Modupe Loye, Thomas A Dix, Ling Wei, Shan Ping Yu
Aging and disease    DOI: 10.14336/AD.2019.0507
Accepted: 13 May 2019

Combined Antioxidant, Anti-inflammaging and Mesenchymal Stem Cell Treatment: A Possible Therapeutic Direction in Elderly Patients with Chronic Obstructive Pulmonary Disease
Shijin Xia, Changxi Zhou, Bill Kalionis, Xiaoping Shuang, Haiyan Ge, Wen Gao
Aging and disease    DOI: 10.14336/AD.2019.0508
Accepted: 11 May 2019

The Clinical Efficacy and Safety of Stem Cell Therapy for Diabetes Mellitus: A Systematic Review and Meta-Analysis
Yazhen Zhang, Wenyi Chen, Bing Feng, Hongcui Cao
Aging and disease    DOI: 10.14336/AD.2019.0421
Accepted: 10 May 2019

Type 2 Myocardial Infarction: A Geriatric Population-based Model of Pathogenesis
Alain Putot, Melanie Jeanmichel², Frederic Chague, Patrick Manckoundia, Yves Cottin, Marianne Zeller
Aging and disease    DOI: 10.14336/AD.2019.0405
Accepted: 08 May 2019

Metastasis Patterns and Prognosis of Octogenarians with NSCLC: A Population-based Study
Yu Gu, Junhua Zhang, Zhirui Zhou, Di Liu, Hongcheng Zhu, Junmiao Wen, Xinyan Xu, Tianxiang Chen, Min Fan
Aging and disease    DOI: 10.14336/AD.2019.0414
Accepted: 07 May 2019

Predictive Value of Pin1 in Cervical Low-Grade Squamous Intraepithelial Lesions and Inhibition of Pin1 Exerts Potent Anticancer Activity against Human Cervical Cancer
Yan-Tong Guo, Yan Lu, Yi-Yang Jia, Hui-Nan Qu, Da Qi, Xin-Qi Wang, Pei-Ye Song, Xiang-Shu Jin, Wen-Hong Xu, Yuan Dong, Ying-Ying Liang, Cheng-Shi Quan*
Aging and disease    DOI: 10.14336/AD.2019.0415
Accepted: 07 May 2019

AmpliSeq Transcriptome of Laser Captured Neurons from Alzheimer Brain: Comparison of Single Cell Versus Neuron Pools
Wenjun Deng, Changhong Xing, Rob David, Diego Mastroeni, MingMing Ning, Eng H. Lo, Paul D. Coleman
Aging and disease    DOI: 10.14336/AD.2019.0225
Accepted: 12 April 2019

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