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Just Accepted
The manuscripts published below have been examined by the peer-review process and have been accepted for publication. A “Just Accepted” manuscript is published online shortly after its acceptance, which is prior to technical editing and formatting and author proofing. Higher Education Press (HEP) provides “Just Accepted” as an optional and free service which allows authors to make their results available to the research community as soon as possible after acceptance. After a manuscript has been technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an Online First article. Please note that technical editing may introduce minor changes to the manuscript text and/or graphics which may affect the content, and all legal disclaimers that apply to the journal pertain. In no event shall HEP be held responsible for errors or consequences arising from the use of any information contained in these “Just Accepted” manuscripts. To cite this manuscript please use its Digital Object Identifier (DOI(r)), which is identical for all formats of publication.
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Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
Jinfan Tian, Mohammad Sharif Popal, Yingke Zhao, Yanfei Liu, Keji Chen, Yue Liu
Aging and disease    DOI: 10.14336/AD.2018.1020
Accepted: 20 November 2018

Health and Aging: Unifying Concepts, Scores, Biomarkers and Pathways
Georg Fuellen, Ludger Jansen, Alan A. Cohen, Walter Luyten, Manfred Gogol, Andreas Simm, Nadine Saul, Francesca Cirulli, Alessandra Berry, Peter Antal, Rüdiger Köhling, Brecht Wouters, Steffen Möller
Aging and disease    DOI: 10.14336/AD.2018.1030
Accepted: 19 November 2018

Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson’s Disease with Mild Cognitive Impairment
Xiuqin Jia, Zhijiang Wang, Tao Yang, Ying Li, Shuai Gao, Guorong Wu, Tao Jiang, Peipeng Liang
Aging and disease    DOI: 10.14336/AD.2018.1116
Accepted: 18 November 2018
Online available: 18 November 2018

MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway
Junfen Fan, Xingyan An, Yanlei Yang, Haoying Xu, Linyuan Fan, Luchan Deng, Tao Li, Xisheng Weng, Jianmin Zhang, Hongling Li, Robert Chunhua Zhao
Aging and disease    DOI: 10.14336/AD.2018.1110
Accepted: 18 November 2018

Role of Regulatory T cells in Atorvastatin Induced Absorption of Chronic Subdural Hematoma in Rats
Wei Quan, Zhifei Zhang, Pan Li, Qilong Tian, Jinhao Huang, Yu Qian, Chuang Gao, Wanqiang Su, Zengguang Wang, Jianning Zhang, Alex Zacharek, Poornima Venkat, Jieli Chen, Rongcai Jiang
Aging and disease    DOI: 10.14336/AD.2018.0926
Accepted: 16 November 2018

TNF𝛼-induced Up-regulation of Ascl2 Affects the Differentiation and Proliferation of Neural Stem Cells
Zhongfeng Liu, Xuan Wang, Kewen Jiang, Xunming Ji, Y. Alex Zhang, Zhiguo Chen
Aging and disease    DOI: 10.14336/AD.2018.1028
Accepted: 16 November 2018

The Potential Markers of Circulating microRNAs and long non-coding RNAs in Alzheimer's Disease
Yanfang Zhao, Yuan Zhang, Lei Zhang, Yanhan Dong, Ji Hongfang, Shen Liang
Aging and disease    DOI: 10.14336/AD.2018.1105
Accepted: 13 November 2018

Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease
Christopher Bi, Stephanie Bi, Bin Li
Aging and disease    DOI: 10.14336/AD.2018.0425
Accepted: 12 November 2018

Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline
Yanqing Wu, Libing Ye, Yuan Yuan, Ting Jiang, Xin Guo, Zhouguang Wang, Ke Xu, Zeping Xu, Yanlong Liu, Xingfeng Zhong, Junmin Ye, Hongyu Zhang, Xiaokun Li, Jian Xiao
Aging and disease    DOI: 10.14336/AD.2018.1024
Accepted: 12 November 2018

Anatomical Links between White Matter Hyperintensity and Medial Temporal Atrophy Reveal Impairment of Executive Functions
Takehiko Yamanaka, Yuto Uchida, Keita Sakurai, Daisuke Kato, Masayuki Mizuno, Toyohiro Sato, Yuta Madokoro, Yuko Kondo, Ayuko Suzuki, Yoshino Ueki, Fumiyasu Ishii, Cesar V Borlongan, Noriyuki Matsukawa
Aging and disease    DOI: 10.14336/AD.2018.0929
Accepted: 09 November 2018

Deficiency of Yes-Associated Protein Induces Cataract in Mice
Qing He, Yuhao Gao, Lujun Zhou, Tongxing Wang, Zengqiang Yuan
Aging and disease    DOI: 10.14336/AD.2018.0910
Accepted: 13 October 2018

The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases
Huachen Huang, Shanshan Song, Suneel Banerjee, Tong Jiang, Jinwei Zhang, Kristopher T. Kahle, Dandan Sun, Zhongling Zhang
Aging and disease    DOI: 10.14336/AD.2018.0928
Accepted: 02 October 2018

Preclinical Evidence and Possible Mechanisms of Extracts or Compounds from Cistanches for Alzheimer’s Disease
Xiao-Li Zhou, Meng-Bei Xu, Ting-Yu Jin, Pei-Qing Rong, Guo-Qing Zheng*, Yan Lin*
Aging and disease    DOI: 10.14336/AD.2018.015
Accepted: 29 September 2018

Calcitriol Analogues Decrease Lung Metastasis but Impair Bone Metabolism in Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Tumours
Artur Anisiewicz, Beata Filip-Psurska, Agata Pawlik, Anna Nasulewicz-Goldeman, Tomasz Piasecki, Konrad Kowalski, Magdalena Maciejewska, Joanna Jarosz, Joanna Banach, Diana Papiernik, Andrzej Mazur, Andrzej Kutner, Jeanette A. Maier, Joanna Wietrzyk
Aging and disease    DOI: 10.14336/AD.2018.0921
Accepted: 28 September 2018

Autoantibodies against AT1 Receptor Contribute to Vascular Aging and Endothelial Cell Senescence
Meili Wang, Xiaochen Yin, Suli Zhang, Chenfeng Mao, Ning Cao, Xiaochun Yang, Jingwei Bian, Weiwei Hao, Qian Fan, Huirong Liu
Aging and disease    DOI: 10.14336/AD.2018.0919
Accepted: 27 September 2018

Intravenous Administration of Standard Dose Tirofiban after Mechanical Arterial Recanalization is Safe and Relatively Effective in Acute Ischemic Stroke
Zhe Cheng, Xiaokun Geng, Jie Gao, Mohammed Hussain, Seong-Jin Moon, Huishan Du, Yuchuan Ding
Aging and disease    DOI: 10.14336/AD.2018.0922
Accepted: 26 September 2018

Duration and Quality of Sleep and Risk of Physical Function Impairment and Disability in Older Adults: Results from the ENRICA and ELSA Cohorts
Marcela Z. Campanini, Arthur E. Mesas, Jose Antonio Carnicero-Carreño, Fernando Rodríguez-Artalejo, Esther Lopez-Garcia
Aging and disease    DOI: 10.14336/AD.2018.0611
Accepted: 23 September 2018

Clinical and Genetic Profiles in Chinese Patients with Huntington’s Disease: A Ten-year Multicenter Study in China
Hong-Lei Li, Xiao-Yan Li, Yi Dong, Yan-Bin Zhang, Hong-Rong Cheng, Shi-Rui Gan, Zhi-Jun Liu, Wang Ni, Jean-Marc Burgunder, X. William Yang, Zhi-Ying Wu
Aging and disease    DOI: 10.14336/AD.2018.0911
Accepted: 22 September 2018

The Metabolic Activity of Caudate and Prefrontal Cortex Negatively Correlates with the Severity of Idiopathic Parkinson’s Disease
Jun-Sheng Chu, Ting-Hong Liu, Kai-Liang Wang, Chun-Lei Han, Yun-Peng Liu, Shimabukuro Michitomo, Jian-Guo Zhang, Tie Fang, Fan-Gang Meng
Aging and disease    DOI: 10.14336/AD.2018.0814
Accepted: 20 September 2018

Glial S100A6 Degrades β-amyloid Aggregation through Targeting Competition with Zinc Ions
Zhi-Ying Tian, Chun-Yan Wang, Tao Wang, Yan-Chun Li, Zhan-You Wang
Aging and disease    DOI: 10.14336/AD.2018.0912
Accepted: 20 September 2018

Enhancement of Mesenchymal Stem Cell-Driven Bone Regeneration by Resveratrol-Mediated SOX2 Regulation
Yoorim Choi, Dong Suk Yoon, Kyoung-Mi Lee, Seong Mi Choi, Myon-Hee Lee, Kwang Hwan Park, Seung Hwan Han, Jin Woo Lee
Aging and disease    DOI: 10.14336/AD.2018.0802
Accepted: 18 September 2018

The Prognostic Value of Serum Cytokines in Patients with Acute Ischemic Stroke
Xianmei Li, Siyang Lin, Xiaoli Chen, Wensi Huang, Qian Li, Hongxia Zhang, Xudong Chen, Shaohua Yang, Kunlin Jin, Bei Shao
Aging and disease    DOI: 10.14336/AD.2018.0820
Accepted: 14 September 2018

Maintained Properties of Aged Dental Pulp Stem Cells for Superior Periodontal Tissue Regeneration
Linsha Ma, Jingchao Hu, Yu Cao, Yilin Xie, Hua Wang, Zhipeng Fan, Chunmei Zhang, Jinsong Wang, Chu-Tse Wu, Songlin Wang
Aging and disease    DOI: 10.14336/AD.2018.0729
Accepted: 12 September 2018

Subclinical Hypothyroidism: is it Really Subclinical with Aging?
Robin Gourmelon, Sandrine Donadio-Andréi, Karim Chikh, Muriel Rabilloud, Elisabetta Kuczewski, Anne-Sophie Gauchez, Anne Charrié, Pierre-Yves Brard, Raphaëlle Andréani, Jean-Cyril Bourre, Christine Waterlot, Domitille Guédel, Anne Mayer, Emmanuel Disse, Charles Thivolet, Hélène Du Boullay, Claire Falandry, Thomas Gilbert, Anne François-Joubert, Antoine Vignoles, Catherine Ronin, Marc Bonnefoy
Aging and disease    DOI: 10.14336/AD.2018.0817
Accepted: 07 September 2018
Online available: 06 September 2018

Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling
Xu-Xu Deng, Shan-Shan Li, Feng-Yan SUN
Aging and disease    DOI: 10.14336/AD.2018.0728
Accepted: 04 September 2018

Traditional Oriental Medicines and Alzheimer’s Disease
Seong Gak Jeon, Eun Ji Song, Dongje Lee, Junyong Park, Yunkwon Nam, Jin-il Kim, Minho Moon
Aging and disease    DOI: 10.14336/AD.2018.0328
Accepted: 29 August 2018

Olfactory Dysfunction and Its Relationship with Clinical Symptoms of Alzheimer Disease
Qiujin Yu, Peng Guo, Danning Li, Lijun Zuo, Tenghong Lian, Shuyang Yu, Yang Hu, Li Liu, Zhao Jin, Ruidan Wang, Yingshan Piao, Lixia Li, Xiaomin Wang, Wei Zhang
Aging and disease    DOI: 10.14336/AD.2018.0819
Accepted: 28 August 2018

Deficiency of tPA Exacerbates White Matter Damage, Neuroinflammation, Glymphatic Dysfunction and Cognitive Dysfunction in Aging Mice
Peng Yu, Poornima Venkat, Michael Chopp, Alex Zacharek, Yi Shen, Linlin Liang, Julie Landschoot-Ward, Zhongwu Liu, Rongcai Jiang, Jieli Chen
Aging and disease    DOI: 10.14336/AD.2018.0816
Accepted: 27 August 2018
Online available: 26 August 2018

Longevity Effect of Liuwei Dihuang in Both Caenorhabditis Elegans and Aged Mice
Weidong Chen, Jinzeng Wang, Jiahao Shi, Xu Yang, Ping Yang, Ning Wang, Sai Yang, Tianpei Xie, Hua Yang, Mengjie Zhang, Haiyun Wang, Jian Fei
Aging and disease    DOI: 10.14336/AD.2018.0604
Accepted: 21 August 2018
Online available: 21 August 2018

Contrast Staining may be Associated with Intracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy
Hong An, Wenbo Zhao, Jianguo Wang, Joshua C. Wright, Omar Elmadhoun, Di Wu, Shuyi Shang, Chuanjie Wu, Chuanhui Li, Longfei Wu, Jian Chen, Jiangang Duan, Hongqi Zhang, Haiqing Song, Yuchuan Ding, Xunming Ji
Aging and disease    DOI: 10.14336/AD.2018.0807
Accepted: 21 August 2018

Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity
Yaiza Potes, Zulema Perez-Martinez, Juan C. Bermejo-Millo Juan, Adrian Rubio-Gonzalez, Maria Fernandez-Fernandez, Manuel Bermudez, et al.
A&D    DOI: 10.14336/AD.2018.0430
Relationship between Hypothyroidism and Endometrial Cancer
Wang Yiqin,Zhou Rong,Wang Jianliu
A&D    DOI: 10.14336/AD.2018.0224
Efficacy and Safety of the Pneumococcal Conjugate-13 Valent Vaccine in Adults
Fawziah Marra, Nirma Khatri Vadlamudi
A&D    DOI: 10.14336/AD.2018.0512
Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging
Christin Weissleder, Guy Barry, Samantha J. Fung, Matthew W. Wong, Kay L. Double, Maree J. Webster, Cynthia Shannon Weickert
A&D    DOI: 10.14336/AD.2018.0317
Muscle Fatigue Does Not Change the Effects on Lower Limbs Strength Caused by Aging and Parkinson’s Disease
Vinicius Alota Ignacio Pereira, Fabio Augusto Barbieri, Alessandro Moura Zagatto, Paulo Cezar Rocha dos Santos, Lucas Simieli, Ricardo Augusto Barbieri, Felipe Pivetta Carpes, Lilian Teresa B. Gobbi
A&D    DOI: 10.14336/AD.2018.0203
Intensive Lipid-Lowering Therapy Ameliorates Asymptomatic Intracranial Atherosclerosis
Miao Huijuan,Yang Yujiao,Wang Han,Huo Linyu,Wang Mengnan,Zhou Yinghua,Hua Yang,Ren Ming,Ren Changhong,Ji Xunming,Yang Qi,Guo Xiuhai
A&D    DOI: 10.14336/AD.2018.0526
Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases
Zhuang Wei,Yue Lifeng,Dang Xiaofang,Chen Fei,Gong Yuewen,Lin Xiaolan,Luo Yumin
A&D    DOI: 10.14336/AD.2018.0511
Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension
Feng-Juan Li, Cheng-Long Zhang, Xiu-Ju Luo, Jun Peng, Tian-Lun Yang
A&D    DOI: 10.14336/AD.2018.0510
Snapshot: Implications for mTOR in Aging-related Ischemia/Reperfusion Injury
Dong Liu, Liqun Xu, Xiaoyan Zhang, Changhong Shi, Shubin Qiao, Zhiqiang Ma, Jiansong Yuan
A&D    DOI: 10.14336/AD.2018.0501
Increased Serum C-reactive Protein and Corpus Callosum Alterations in Older Adults
Fabienne Cyprien, Philippe Courtet, Jerome Maller, Chantal Meslin, Karen Ritchie, Marie-Laure Ancelin, Sylvaine Artero
A&D    DOI: 10.14336/AD.2018.0329
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