Aging and disease

Table of Content

04 December 2018. VOL 9, ISSUE 6 Previous Issue Next Issue

Orginal Article

Relationship between White Matter Hyperintensities and Hematoma Volume in Patients with Intracerebral Hematoma
Xuemei Chen, Yuexinzi Jin, Jian Chen, Xin Chen, Xiang Cao, Linjie Yu, Yun Xu

2018, 9 (6): 999-1009 | DOI: 10.14336/AD.2018.0108

PDF (664KB)
Association between Leukoaraiosis and Symptomatic Intracranial Large Artery Stenoses and Occlusions: the Chinese Intracranial Atherosclerosis (CICAS) Study
Wanying Duan, Yuehua Pu, Haiyan Liu, Jing Jing, Yuesong Pan, Xinying Zou, Yilong Wang, Xingquan Zhao, Chunxue Wang, Yongjun Wang, Ka Sing Lawrence Wong, Ling Wei, Liping Liu, on behalf of the CICAS StudyGroup

2018, 9 (6): 1074-1083 | DOI: 10.14336/AD.2018.0118

PDF (533KB)

Review

Therapeutic Potential and Effective Components of the Chinese Herb Gardeniae Fructus in the Treatment of Senile Disease
Shichao Lv, Yang Ding, Haiping Zhao, Shihao Liu, Junping Zhang, Jun Wang

2018, 9 (6): 1153-1164 | DOI: 10.14336/AD.2018.0112

PDF (502KB)
Molecular Bases of Alzheimer’s Disease and Neurodegeneration: The Role of Neuroglia
Antonina Luca, Carmela Calandra, Maria Luca

2018, 9 (6): 1134-1152 | DOI: 10.14336/AD.2018.0201

PDF (530KB)

Orginal Article

Relationship between Cortical Thickness and Neuropsychological Performance in Normal Older Adults and Those with Mild Cognitive Impairment
Calvin Pak-Wing Cheng, Sheung-Tak Cheng, Cindy Woon-Chi Tam, Wai-Chi Chan, Winnie Chiu-Wing Chu, Linda Chiu-Wa Lam

2018, 9 (6): 1020-1030 | DOI: 10.14336/AD.2018.0125

PDF (610KB)
Stronger Association between Insomnia Symptoms and Shorter Telomere Length in Old HIV-Infected Patients Compared with Uninfected Individuals
Yingying Ding, Haijiang Lin, Sujuan Zhou, Keran Wang, Lingling Li, Yucheng Zhang, Yuan Yao, Meiyang Gao, Xing Liu, Na He

2018, 9 (6): 1010-1019 | DOI: 10.14336/AD.2018.0204

PDF (637KB)
Intracranial Atherosclerosis Burden and Stroke Recurrence for Symptomatic Intracranial Artery Stenosis (sICAS)
Ping Sun, Liping Liu, Yuesong Pan, Xianwei Wang, Donghua Mi, Yuehua Pu, Xin Liu, Wanying Duan, Hongyi Yan, Chunxue Wang, Xingquan Zhao, Yilong Wang, Yongjun Wang, on behalf of CICAS investigators

2018, 9 (6): 1096-1102 | DOI: 10.14336/AD.2018.0301

PDF (575KB)
Omi/HtrA2 Participates in Age-Related Autophagic Deficiency in Rat Liver
Jiahui Xu, Kun Jiao, Xin Liu, Qi Sun, Ke Wang, Haibo Xu, Shangyue Zhang, Ye Wu, Linguo Wu, Dan Liu, Wen Wang, Huirong Liu

2018, 9 (6): 1031-1042 | DOI: 10.14336/AD.2018.0221

PDF (1815KB)
A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder
Yu-Wen Huang, Ming-Fu Chiang, Che-Sheng Ho, Pi-Lien Hung, Mei-Hsin Hsu, Tsung-Han Lee, Lichieh Julie Chu, Hsuan Liu, Petrus Tang, Wailap Victor Ng, Dar-Shong Lin

2018, 9 (6): 1043-1057 | DOI: 10.14336/AD.2018.0222

PDF (1236KB)
Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection
Manuel Scimeca, Federica Centofanti, Monica Celi, Elena Gasbarra, Giuseppe Novelli, Annalisa Botta, Umberto Tarantino

2018, 9 (6): 952-964 | DOI: 10.14336/AD.2018.0215

PDF (1144KB)
MiRNA-10b Reciprocally Stimulates Osteogenesis and Inhibits Adipogenesis Partly through the TGF-β/SMAD2 Signaling Pathway
Hongling Li, Junfen Fan, Linyuan Fan, Tangping Li, Yanlei Yang, Haoying Xu, Luchan Deng, Jing Li, Tao Li, Xisheng Weng, Shihua Wang, Robert Chunhua Zhao

2018, 9 (6): 1058-1073 | DOI: 10.14336/AD.2018.0214

PDF (1848KB)
Age-Related Changes in Femoral Head Trabecular Microarchitecture
Charlene Greenwood, John Clement, Anthony Dicken, Paul Evans, Iain Lyburn, Richard M. Martin, Nick Stone, Peter Zioupos, Keith Rogers

2018, 9 (6): 976-987 | DOI: 10.14336/AD.2018.0124

PDF (766KB)
Muscle Fatigue Does Not Change the Effects on Lower Limbs Strength Caused by Aging and Parkinson’s Disease
Vinicius Alota Ignacio Pereira, Fabio Augusto Barbieri, Alessandro Moura Zagatto, Paulo Cezar Rocha dos Santos, Lucas Simieli, Ricardo Augusto Barbieri, Felipe Pivetta Carpes, Lilian Teresa Bucken Gobbi

2018, 9 (6): 988-998 | DOI: 10.14336/AD.2018.0203

PDF (642KB)
Olfactory Dysfunction and Its Relationship with Clinical Symptoms of Alzheimer Disease
Qiujin Yu, Peng Guo, Danning Li, Lijun Zuo, Tenghong Lian, Shuyang Yu, Yang Hu, Li Liu, Zhao Jin, Ruidan Wang, Yingshan Piao, Lixia Li, Xiaomin Wang, Wei Zhang

2018, 9 (6): 1084-1095 | DOI: 10.14336/AD.2018.0819

PDF (461KB)
Supplement

1. Supplemental data.pdf (85KB)
MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway
Junfen Fan, Xingyan An, Yanlei Yang, Haoying Xu, Linyuan Fan, Luchan Deng, Tao Li, Xisheng Weng, Jianmin Zhang, Robert Chunhua Zhao

2018, 9 (6): 1103-1121 | DOI: 10.14336/AD.2018.1110

PDF (2316KB)
Supplement

1. Supplemental data.pdf (1054KB)

Review

Emerging Anti-Aging Strategies - Scientific Basis and Efficacy
Ashok K. Shetty, Maheedhar Kodali, Raghavendra Upadhya, Leelavathi N. Madhu

2018, 9 (6): 1165-1184 | DOI: 10.14336/AD.2018.1026

PDF (481KB)
Supplement

1. .pdf (553KB)

Orginal Article

Remote Ischemic Conditioning Protects Diabetic Retinopathy in Streptozotocin-induced Diabetic Rats via Anti-Inflammation and Antioxidation
Changhong Ren, Hang Wu, Dongjie Li, Yong Yang, Yuan Gao, Yunneng Jizhang, Dachuan Liu, Xunming Ji, Xuxiang Zhang

2018, 9 (6): 1122-1133 | DOI: 10.14336/AD.2018.0711

PDF (1126KB)

Cover Illustration

04 December 2018. Vol.9 No.6
Figure 10. Embryonic development and organization structure of TE/SJ/ mesenchymal tissue system. Mesenchymal tissue system consists of mesodermal-derived all kinds of cells (Flk+Lin-/KLF4+GMNN+) from postembryonic subtotipotent stem cells to functional cells in different stages of the embryonic development. In mammals, the intraembryonic coelom is a fluid-filled cavity with the somatic and the visceral mesoderm layers, which then forms TE/SJ/mesenchymal tissue system. Meanwhile, TE/SJ/mesenchymal tissue system constitutes the source of major organs and is the connecting pathway between them. It is involved in the proliferation and differentiation of stem cells, tissue regeneration, and functional reconstruction. It also participates in human immune surveillance, cellular senescence and tissue metabolic.

[Detail]

Cover Illustration

Figure 10. Embryonic development and organization structure of TE/SJ/ mesenchymal tissue system. Mesenchymal tissue system consists of mesodermal-derived all kinds of cells (Flk+Lin-/KLF4+GMNN+) from postembryonic subtotipotent stem cells to functional cells in different stages of the embryonic development. In mammals, the intraembryonic coelom is a fluid-filled cavity with the somatic and the visceral mesoderm layers, which then forms TE/SJ/mesenchymal tissue system. Meanwhile, TE/SJ/mesenchymal tissue system constitutes the source of major organs and is the connecting pathway between them. It is involved in the proliferation and differentiation of stem cells, tissue regeneration, and functional reconstruction. It also participates in human immune surveillance, cellular senescence and tissue metabolic.

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