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2022
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Total 40 results are found
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
2024, 15 (2): 445-448 | DOI: 10.14336/AD.2023.0707-1
Supplement

1. Supplementary data.pdf (2374KB)

Hypoxia and the Aging Cardiovascular System
Antoine Raberin, Johannes Burtscher, Martin Burtscher, Grégoire P. Millet
2023, 14 (6): 2051-2070 | DOI: 10.14336/AD.2023.0424
Longevity-Associated Transcription Factor ATF7 Promotes Healthspan by Suppressing Cellular Senescence and Systematic Inflammation
Yaqun Huang, Ming-Xia Ge, Yu-Hong Li, Jing-Lin Li, Qin Yu, Fu-Hui Xiao, Hong-Shun Ao, Li-Qin Yang, Ji Li, Yonghan He, Qing-Peng Kong
2023, 14 (4): 1374-1389 | DOI: 10.14336/AD.2022.1217
Supplement

1. Supplementary data.pdf (633KB)

Investigating Causality and Shared Genetic Architecture between Neurodegenerative Disorders and Inflammatory Bowel Disease
Ruijie Zeng, Jinghua Wang, Rui Jiang, Jie Yang, Chunwen Zheng, Huihuan Wu, Zewei Zhuo, Qi Yang, Jingwei Li, Felix W Leung, Weihong Sha, Hao Chen
2023, 14 (4): 1349-1359 | DOI: 10.14336/AD.2022.12209
Gut Microbiota is an Impact Factor based on the Brain-Gut Axis to Alzheimer’s Disease: A Systematic Review
Bin Zou, Jia Li, Rui-Xia Ma, Xiao-Yu Cheng, Rui-Yin Ma, Ting-Yuan Zhou, Zi-Qi Wu, Yao Yao, Juan Li
2023, 14 (3): 964-1678 | DOI: 10.14336/AD.2022.1127
Post-Stroke Neuropsychiatric Complications: Types, Pathogenesis, and Therapeutic Intervention
Jing Zhou, Yijia Fangma, Zhong Chen, Yanrong Zheng
2023, 14 (6): 2127-2152 | DOI: 10.14336/AD.2023.0310-2
TGF-β as A Master Regulator of Aging-Associated Tissue Fibrosis
Li-Li Ren, Hua Miao, Yan-Ni Wang, Fei Liu, Ping Li, Ying-Yong Zhao
2023, 14 (5): 1633-1650 | DOI: 10.14336/AD.2023.0222
The Emerging Role of Interleukin-(IL)-11/IL-11R in Bone Metabolism and Homeostasis: From Cytokine to Osteokine
Bingzi Dong, Jingjing Zhu, Xian Chen, Hongyuan Jiang, Yujie Deng, Lili Xu, Yangang Wang, Shufa Li
2023, 14 (6): 2113-2126 | DOI: 10.14336/AD.2023.0306
Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function
Xiaodan Liu, Giuseppe Barisano, Xingfeng Shao, Kay Jann, John M. Ringman, Hanzhang Lu, Konstantinos Arfanakis, Arvind Caprihan, Charles DeCarli, Brian T. Gold, Pauline Maillard, Claudia L. Satizabal, Elyas Fadaee, Mohamad Habes, Lara Stables, Herpreet Singh, Bruce Fischl, Andre van der Kouwe, Kristin Schwab, Karl G. Helmer, Steven M. Greenberg, Danny J.J. Wang, for the MarkVCID Consortium
| DOI: 10.14336/AD.2023.0321-2
Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals
Cyrus A. Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A. Merrill, Rajpaul Attariwala
| DOI: 10.14336/AD.2023.0820
The Role of cGAS-STING in Age-Related Diseases from Mechanisms to Therapies
Weitao Zheng, Dechao Feng, Xingyu Xiong, Xinyang Liao, Sheng Wang, Hang Xu, Weizhen Le, Qiang Wei, Lu Yang
2023, 14 (4): 1145-1165 | DOI: 10.14336/AD.2023.0117
Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators
Hui Xu, Yi-Yang Liu, Lin-Seng Li, You-Shuo Liu
2023, 14 (3): 794-824 | DOI: 10.14336/AD.2022.1123
Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Sajid Ur Rahman, Abdul Qadeer, Ziyun Wu
2024, 15 (2): 565-583 | DOI: 10.14336/AD.2023.0519-1
Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies
Yinrou Huang, Mengke Zhao, Xuemei Chen, Ruoyu Zhang, Anh Le, Michael Hong, Yufei Zhang, Lin Jia, Weidong Zang, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wang
2023, 14 (3): 858-878 | DOI: 10.14336/AD.2022.0916
C-Phycocyanin Ameliorates the Senescence of Mesenchymal Stem Cells through ZDHHC5-Mediated Autophagy via PI3K/AKT/mTOR Pathway
Guoxiang Liu, Xiaoxia Li, Fanghao Yang, Jingyu Qi, Lipeng Shang, Huhu Zhang, Shuang Li, Fenghua Xu, Lingne Li, Huaxin Yu, Yang Li, Xiaolei Dong, Qinghang Song, Feng Zhu, Guang Chen, Can Cao, Liangqian Jiang, Junzhe Su, Lina Yang, Xiaohui Xu, Zhe Zhang, Robert Chunhua Zhao, Bing Li
2023, 14 (4): 1425-1440 | DOI: 10.14336/AD.2023.0121
Supplement

1. Supplementary data.pdf (186KB)

Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer’s Disease and Parkinson’s Disease
Jing Yang, Wei Zhang, Shugeng Zhang, Ashok Iyaswamy, Jichao Sun, Jigang Wang, Chuanbin Yang
2023, 14 (3): 652-669 | DOI: 10.14336/AD.2022.0927
Mitochondria-mediated Ferroptosis in Diseases Therapy: From Molecular Mechanisms to Implications
Fuhai Feng, Shasha He, Xiaoling Li, Jiake He, Lianxiang Luo
2024, 15 (2): 714-738 | DOI: 10.14336/AD.2023.0717
Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation
Yu Chen, Junren Chen, Ziwei Xing, Cheng Peng, Dan Li
2024, 15 (2): 739-754 | DOI: 10.14336/AD.2023.0718-1
Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
Qianting Deng, Chongyun Wu, Emily Parker, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
| DOI: 10.14336/AD.2023.0907
Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity
Cyril Statzer, Ji Young Cecilia Park, Collin Y Ewald
2023, 14 (3): 670-693 | DOI: 10.14336/AD.2022.1116
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway
Ruoyan Xue, Mengyao Xie, Zhiyuan Wu, Shu Wang, Yongli Zhang, Zhijin Han, Chen Li, Qi Tang, Liping Wang, Di Li, Shihua Wang, Hua Yang, Robert Chunhua Zhao
2024, 15 (2): 851-868 | DOI: 10.14336/AD.2023.0719-1
Supplement

1. Supplementary data.pdf (505KB)

Exercise Improves Metabolism and Alleviates Atherosclerosis via Muscle-Derived Extracellular Vesicles
Yixiao Wang, Yunnan Liu, Siyan Zhang, Na Li, Changyang Xing, Chen Wang, Jia Wang, Mengying Wei, Guodong Yang, Lijun Yuan
2023, 14 (3): 952-965 | DOI: 10.14336/AD.2022.1131
Molecular mechanisms of phase separation and amyloidosis of ALS/FTD-linked FUS and TDP-43
Jianxing Song
| DOI: 10.14336/AD.2023.1118
Molecular Regulation Mechanism of Microglial Autophagy in the Pathology of Alzheimer's Disease
Pei Ou-Yang, Zhi-Yu Cai, Zhong-Hao Zhang
2023, 14 (4): 1166-1177 | DOI: 10.14336/AD.2023.0106
NFATc3 Promotes Pulmonary Inflammation and Fibrosis by Regulating Production of CCL2 and CXCL2 in Macrophages
Yunjuan Nie, Xiaorun Zhai, Jiao Li, Aijuan Sun, Huilian Che, John W Christman, Gaoshang Chai, Peng Zhao, Manjula Karpurapu
2023, 14 (4): 1441-1457 | DOI: 10.14336/AD.2022.1202
Complications of COVID-19 on the Central Nervous System: Mechanisms and Potential Treatment for Easing Long COVID
Zhuang-Yao D Wei, Ketty Liang, Ashok K Shetty
2023, 14 (5): 1492-1510 | DOI: 10.14336/AD.2023.0312
Hallmarks of Skin Aging: Update
Shifeng Jin, Kezhu Li, Xuanru Zong, Seokchan Eun, Naoki Morimoto, Shu Guo
2023, 14 (6): 2167-2176 | DOI: 10.14336/AD.2023.0321
Targeting Mitochondrial Sirtuins in Age-Related Neurodegenerative Diseases and Fibrosis
Haoxiang Xiao, Yuqiao Xie, Kaiwen Xi, Jinyi Xie, Mingyue Liu, Yangming Zhang, Zishuo Cheng, Wenting Wang, Baolin Guo, Shengxi Wu
2023, 14 (5): 1583-1605 | DOI: 10.14336/AD.2023.0203
SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease
Xuemeng Miao, Qian Wu, Siyu Du, Ludan Xiang, Siyao Zhou, Junzhe Zhu, Zirun Chen, Hui Wang, Xuyi Pan, Yiren Fan, Lihan Zhang, Jingkang Qian, Yuxuan Xing, Yiyang Xie, Lixin Hu, Haiyun Xu, Wei Wang, Ying Wang, Zhihui Huang
2024, 15 (1): 390-407 | DOI: 10.14336/AD.2023.0516-1
Supplement

1. Supplementary data.pdf (1704KB)

Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia
Wenze Deng, Pengcheng Yi, Yanhong Xiong, Jun Ying, Yue Lin, Yao Dong, Gen Wei, Xifeng Wang, Fuzhou Hua
2024, 15 (2): 480-502 | DOI: 10.14336/AD.2023.0727
A New Landscape of Human Dental Aging: Causes, Consequences, and Intervention Avenues
Yajia Xie, Shuang Chen, Lu Sheng, Yu Sun, Shangfeng Liu
2023, 14 (4): 1123-1144 | DOI: 10.14336/AD.2022.1224
COVID-19 and Cardiovascular Diseases: From Cellular Mechanisms to Clinical Manifestations
Hongyang Shu, Zheng Wen, Na Li, Zixuan Zhang, Bala Musa Ceesay, Yizhong Peng, Ning Zhou, Dao Wen Wang
2023, 14 (6): 2071-2088 | DOI: 10.14336/AD.2023.0314
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression
Zhengshuai Song, Qi Cao, Bin Guo, Ye Zhao, Xuechao Li, Ning Lou, Chenxi Zhu, Gang Luo, Song Peng, Guohao Li, Ke Chen, Yong Wang, Hailong Ruan, Yonglian Guo
2023, 14 (5): 1757-1774 | DOI: 10.14336/AD.2023.0202
Supplement

1. Supplementary data.pdf (764KB)

The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Yang Yu, Ran Chen, Kaiyue Mao, Maoyan Deng, Zhigang Li
2024, 15 (2): 459-479 | DOI: 10.14336/AD.2023.0718
Glycometabolic Reprogramming of Microglia in Neurodegenerative Diseases: Insights from Neuroinflammation
Qi Huang, Yanfu Wang, Shanshan Chen, Fengxia Liang
| DOI: 10.14336/AD.2023.0807
Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses
Mohammad Nasb, Weichu Tao, Ning Chen
2024, 15 (1): 43-73 | DOI: 10.14336/AD.2023.0608
TAK1 Improves Cognitive Function via Suppressing RIPK1-Driven Neuronal Apoptosis and Necroptosis in Rats with Chronic Hypertension
Jing Yang, Pei Sun, Xiangming Xu, Xiaolu Liu, Linfang Lan, Ming Yi, Chi Xiao, Ruichen Ni, Yuhua Fan
2023, 14 (5): 1799-1817 | DOI: 10.14336/AD.2023.0219
Supplement

1. Supplementary data.pdf (447KB)

Clearance of Stress-Induced Premature Senescent Cells Alleviates the Formation of Abdominal Aortic Aneurysms
Jingfang Xie, Zhenquan Tang, Qiqi Chen, Xiaoqian Jia, Chuling Li, Ming Jin, Guoquan Wei, Hao Zheng, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin, Senlin Huang
2023, 14 (5): 1778-1798 | DOI: 10.14336/AD.2023.0215
Supplement

1. Supplementary data.pdf (1549KB)

How are Aging and Osteoarthritis Related?
Shital Wakale, Xiaoxin Wu, Yogita Sonar, Antonia Sun, Xiwei Fan, Ross Crawford, Indira Prasadam
2023, 14 (3): 592-604 | DOI: 10.14336/AD.2022.0831
Myasthenia Gravis: Novel Findings and Perspectives on Traditional to Regenerative Therapeutic Interventions
Evelyn Jou-Chen Huang, Meng-Huang Wu, Tsung-Jen Wang, Tsung-Jen Huang, Yan-Rong Li, Ching-Yu Lee
2023, 14 (4): 1070-1092 | DOI: 10.14336/AD.2022.1215