ISOAD Become a Member Search
2024
Impact Factor
6.9

Most Downloaded

  • Published in last 1 year
  • In last 2 years
  • In last 3 years
  • All
  • Most Downloaded in Recent Month
  • Most Downloaded in Recent Year
Please wait a minute...
Total 40 results are found
Age-Related Dysfunction in Balance: A Comprehensive Review of Causes, Consequences, and Interventions
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
2025, 16 (2): 714-737 | DOI: 10.14336/AD.2024.0124-1
Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
2025, 16 (2): 980-1002 | DOI: 10.14336/AD.2024.0331
Exercise-Induced Central Fatigue: Biomarkers and Non-Medicinal Interventions
Ying Yang, Zhi Feng, Yu-hang Luo, Jue-miao Chen, Yu Zhang, Yi-jun Liao, Hui Jiang, Yinxi Long, Bo Wei
2025, 16 (3): 1302-1315 | DOI: 10.14336/AD.2024.0567
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training
Daniel G. Blackmore, Mia A. Schaumberg, Maryam Ziaei, Samuel Belford, Xuan Vinh To, Imogen O’Keeffe, Anne Bernard, Jules Mitchell, Emily Hume, Grace L. Rose, Thomas Shaw, Ashley York, Markus Barth, Elizabeth J. Cooper, Tina L. Skinner, Fatima Nasrallah, Stephan Riek, Perry F. Bartlett
2025, 16 (3): 1732-1754 | DOI: 10.14336/AD.2024.0642
Supplement

1. Supplementary data.pdf (6754KB)

Cerebral Small Vessel Disease: Current and Emerging Therapeutic Strategies
Yuewen Sun, Xiaoqian Song, Chenyang Jin, Yilong Peng, Jing Zhou, Xueping Zheng
2026, 17 (1): 286-303 | DOI: 10.14336/AD.2024.1515
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
2025, 16 (2): 917-945 | DOI: 10.14336/AD.2024.0083
The Expanding Burden of Neurodegenerative Diseases: An Unmet Medical and Social Need
Shu Wang, Yin Jiang, Anchao Yang, Fangang Meng, Jianguo Zhang
2025, 16 (5): 2937-2952 | DOI: 10.14336/AD.2024.1071
Therapeutic Potential of Quercetin as an Antioxidant for Bone-Muscle-Tendon Regeneration and Aging
Jae Gyu Kim, Ashish Ranjan Sharma, Yeon-Hee Lee, Srijan Chatterjee, Yean Jung Choi, Roshani Rajvansh, Chiranjib Chakraborty, Sang-Soo Lee
2025, 16 (3): 1414-1437 | DOI: 10.14336/AD.2024.0282
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov, Natasha S. Barteneva
2025, 16 (3): 1242-1264 | DOI: 10.14336/AD.2024.0526
Aging and “Age-Related” Diseases - What Is the Relation?
Wolfgang Kopp
2025, 16 (3): 1316-1346 | DOI: 10.14336/AD.2024.0570
The Role of Liquid-Liquid Phase Separation in the Accumulation of Pathological Proteins: New Perspectives on the Mechanism of Neurodegenerative Diseases
Xingyu Lu, Jiongtong Lu, Shengnan Li, Sifan Feng, Yan Wang, Lili Cui
2025, 16 (2): 769-786 | DOI: 10.14336/AD.2024.0209
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies
Yonglian Chen, Jinhui Wu
2025, 16 (2): 1003-1022 | DOI: 10.14336/AD.2024.0407
Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
Guiqin Zhang, Priyadarshani Nadeeshika Samarawickrama, Li Gui, Yuan Ma, Mei Cao, Hong Zhu, Wei Li, Honglin Yang, Kecheng Li, Yang Yang, Enfang Zhu, Wen Li, Yonghan He
2025, 16 (2): 946-970 | DOI: 10.14336/AD.2024.0065
Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies
Xin-ran Zhao, Jia-bin Zong, Yu-xiao Liu, Tuersun Aili, Min Qiu, Jie-hong Wu, Bo Hu
2025, 16 (2): 738-756 | DOI: 10.14336/AD.2024.0123-1
Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis
Arubala P. Reddy, Priyanka Rawat, Nicholas Rohr, Razelle Alvir, Jasbir Bisht, Mst Anika Bushra, Jennifer Luong, Aananya P. Reddy
2025, 16 (2): 841-858 | DOI: 10.14336/AD.2024.0328
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice
Mengpei Zhu, Yumei Huang, Ziwen Wang, Ze Jin, Jiali Cao, Qiangqiang Zhong, Zhifan Xiong
2025, 16 (2): 1180-1198 | DOI: 10.14336/AD.2024.0321
Supplement

1. Supplementary data.pdf (500KB)

Mitochondrial Dysfunction: A Roadmap for Understanding and Tackling Cardiovascular Aging
Han Zhang, Mairedan Muhetarijiang, Ryan J. Chen, Xiaosheng Hu, Jie Han, Liangrong Zheng, Ting Chen
2025, 16 (5): 2575-2614 | DOI: 10.14336/AD.2024.0058
Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential
Qianting Deng, Emily Parker, Chongyun Wu, Ling Zhu, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
2025, 16 (2): 804-840 | DOI: 10.14336/AD.2024.0239
Cell-Free DNA As Peripheral Biomarker of Alzheimer’s Disease
Sachi Khemka, Ujala Sehar, Pulak R Manna, Sudhir Kshirsagar, P. Hemachandra Reddy
2025, 16 (2): 787-803 | DOI: 10.14336/AD.2024.0329
Green Tea Mitigates the Hallmarks of Aging and Age-Related Multisystem Deterioration
Yusuf Yilmaz
| DOI: 10.14336/AD.2025.0398
Amyloid-β and Phosphorylated Tau are the Key Biomarkers and Predictors of Alzheimer’s Disease
Jangampalli Adi Pradeepkiran, Javaria Baig, Md Ariful Islam, Sudhir Kshirsagar, P. Hemachandra Reddy
2025, 16 (2): 658-682 | DOI: 10.14336/AD.2024.0286
Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis
Jiaqi Xin, Sen Huang, Jing Wen, Yunhao Li, Ang Li, Senthil Kumaran Satyanarayanan, Xiaoli Yao, Huanxing Su
2025, 16 (2): 693-713 | DOI: 10.14336/AD.2024.0440
Gut Microbiota and Its Metabolites: The Emerging Bridge Between Coronary Artery Disease and Anxiety and Depression?
Haiyang Chen, Lijun Zhang, Yanwei Li, Xiangxi Meng, Yunpeng Chi, Meiyan Liu
2025, 16 (3): 1265-1284 | DOI: 10.14336/AD.2024.0538
The Role of the Complement System in Synaptic Pruning after Stroke
Hongying Liu, Min Jiang, Zhiying Chen, Chuan Li, Xiaoping Yin, Xiaorong Zhang, Moxin Wu
2025, 16 (3): 1452-1470 | DOI: 10.14336/AD.2024.0373
Targeting the Ophthalmic Diseases Using Extracellular Vesicles ‘Exosomes’: Current Insights on Their Clinical Approval and Present Trials
Hanxiang Yu, Jinsong Wu, Gaoxiang Pan
2025, 16 (3): 1225-1241 | DOI: 10.14336/AD.2024.0535
Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells
Chih-Ru Lin, Hassan Hayek, Hannah Simborio, Loukmane Karim, Karim Bahmed, Sudhir Bolla, Nathaniel Marchetti, Gerard J. Criner, Ying Tian, Beata Kosmider
2026, 17 (1): 367-382 | DOI: 10.14336/AD.2024.1175
Recent Advances in Our Understanding of Age-Related Macular Degeneration: Mitochondrial Dysfunction, Redox Signaling, and the Complement System
Francesco Buonfiglio, Christina A. Korb, Bernhard Stoffelns, Norbert Pfeiffer, Adrian Gericke
2025, 16 (3): 1535-1575 | DOI: 10.14336/AD.2024.0124
The NRF2/ID2 Axis in Vascular Smooth Muscle Cells: Novel Insights into the Interplay between Vascular Calcification and Aging
Mulin Xu, Xiuxian Wei, Jinli Wang, Yi Li, Yi Huang, Anying Cheng, Fan He, Le Zhang, Cuntai Zhang, Yu Liu
2025, 16 (2): 1120-1140 | DOI: 10.14336/AD.2024.0075
Supplement

1. Supplementary data.pdf (1137KB)

Skin-brain axis in Alzheimer's disease - Pathologic, diagnostic, and therapeutic implications: A Hypothetical Review
Hyeon soo Kim, Haram Jung, Yong Ho Park, Su-Hak Heo, Sujin Kim, Minho Moon
2025, 16 (2): 901-916 | DOI: 10.14336/AD.2024.0406
Enhanced Chondrogenic Potential and Osteoarthritis Treatment Using Cyaonoside A-Induced MSC Delivered via a Hyaluronic Acid-Based Hydrogel System
Xingyan An, Qirong Zhou, Shihao Sheng, Anfu Deng, Han Liu, Xiuhui Wang, Qin Zhang, Yingying Jing, Ke Xu, Chongru He, Robert Chunhua Zhao, Jiacan Su
2026, 17 (1): 466-482 | DOI: 10.14336/AD.2024.10016
Supplement

1. Supplementary data.pdf (810KB)

Current Understanding of Marginal Grafts in Liver Transplantation
Ze Xiang, Jiarui Li, Huixuan Zeng, Xiaonan Xiang, Fengqiang Gao, Kai Wang, Xuyong Wei, Shusen Zheng, Xiao Xu
2025, 16 (2): 1036-1058 | DOI: 10.14336/AD.2024.0214
Brain Iron Dyshomeostasis and Ferroptosis in Alzheimer’s Disease Pathophysiology: Two Faces of the Same Coin
Mariarosa Mezzanotte, Serena Stanga
2025, 16 (5): 2615-2640 | DOI: 10.14336/AD.2024.0094
Excitotoxicity, Oxytosis/Ferroptosis, and Neurodegeneration: Emerging Insights into Mitochondrial Mechanisms
Sameera Khan, Nargis Bano, Shakir Ahamad, Urmilla John, Nawab John Dar, Shahnawaz Ali Bhat
2025, 16 (5): 2504-2543 | DOI: 10.14336/AD.2024.0125-1
Supplement

1. Supplementary data.pdf (290KB)

Expert Consensus on Prevention and Treatment of Aging-Related Gonadal Dysfunction
Xi Wang, Li Ma, Sheng Jiang, Junping Wen, Zhaoli Yan, Long Tian, Shan Deng, Boxian Huang, Ilia Stambler, Calogero Caruso, Kyung-Jin Min, Huanxing Su, Kunlin Jin, Jiangfeng Mao, Xueyan Wu, Qin Han, Robert Chunhua Zhao
2025, 16 (2): 971-979 | DOI: 10.14336/AD.2024.0004
Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment
Yiming Pan, Lina Ma
2025, 16 (2): 859-875 | DOI: 10.14336/AD.2024.0258
Association between Body Iron Status and Cognitive Task Performance in a Nationally Representative Sample of Older Adults
Jianying Peng, Buyun Liu, Wei Tan, Shouzhang Hu, Benchao Li, Jin Zhou, Guifeng Xu, Yangbo Sun, Linda G. Snetselaar, Robert B. Wallace, Shuang Rong, Wei Bao
2025, 16 (2): 1141-1148 | DOI: 10.14336/AD.2019.0064
Supplement

1. Supplementary data.pdf (382KB)

Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer
Guanhua Yi, Haixin Luo, Yalin Zheng, Wenjing Liu, Denian Wang, Yong Zhang
2025, 16 (2): 876-900 | DOI: 10.14336/AD.2024.0409
Expert Consensus on the Application of Stem Cells in Psoriasis Research and Clinical Trials
Ye-Hong Kuang, Wu Zhu, Ge Lin, La-Mei Cheng, Qun Qin, Zhi-Jun Huang, Yu-Ling Shi, Chun-Lei Zhang, Jin-Hua Xu, Ke-Xiang Yan, Cheng-Zhi Lv, Wei Li, Qin Han, Ilia Stambler, Lee Wei Lim, Sasanka Chakrabarti, Brun Ulfhake, Kyung-Jin Min, Georgina Ellison-Hughes, William C Cho, Kunlin Jin, Danni Yao, Chuanjian Lu, Robert Chunhua Zhao, Xiang Chen
2025, 16 (3): 1363-1377 | DOI: 10.14336/AD.2024.0012
The Organ-Joint Axes in Osteoarthritis: Significant Pathogenesis and Therapeutic Targets
Dinglong Yang, Yujing Chen, Junfei Guo, Xin Xu, Mingyi Yang, Jiale Xie, Ke Xu, Peng Xu
2025, 16 (5): 2999-3021 | DOI: 10.14336/AD.2024.1223
SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence
Alicia Villacampa, Licia Shamoon, Inés Valencia, Cristina Morales, Sofía Figueiras, Fernando de la Cuesta, Dolores Sánchez-Niño, Guillermo Díaz-Araya, Isabel Sánchez-Pérez, Óscar Lorenzo, Carlos Félix Sánchez-Ferrer, Concepción Peiró
2025, 16 (3): 1626-1638 | DOI: 10.14336/AD.2024.0405
Supplement

1. Supplementary data.pdf (737KB)