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Total 40 results are found
Age-Related Dysfunction in Balance: A Comprehensive Review of Causes, Consequences, and Interventions
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
2025, 16 (2): 714-737 | DOI: 10.14336/AD.2024.0124-1
Consequences of Aging on Bone
Lingli Zhang, Qiao Guan, Zhikun Wang, Jie Feng, Jun Zou, Bo Gao
2024, 15 (6): 2417-2452 | DOI: 10.14336/AD.2023.1115
Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
2025, 16 (2): 980-1002 | DOI: 10.14336/AD.2024.0331
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training
Daniel G. Blackmore, Mia A. Schaumberg, Maryam Ziaei, Samuel Belford, Xuan Vinh To, Imogen O’Keeffe, Anne Bernard, Jules Mitchell, Emily Hume, Grace L. Rose, Thomas Shaw, Ashley York, Markus Barth, Elizabeth J. Cooper, Tina L. Skinner, Fatima Nasrallah, Stephan Riek, Perry F. Bartlett
2025, 16 (3): 1732-1754 | DOI: 10.14336/AD.2024.0642
Supplement

1. Supplementary data.pdf (6754KB)

Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43
Jianxing Song
2024, 15 (5): 2084-2112 | DOI: 10.14336/AD.2023.1118
The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds
Wenjie He, Ming Tang, Rifang Gu, Xingqian Wu, Xinrui Mu, Xuqiang Nie
2025, 16 (1): 373-393 | DOI: 10.14336/AD.2024.0212
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies
Liyao Zheng, Shipei He, Hong Wang, Jinling Li, Yuanyuan Liu, Sijia Liu
2024, 15 (6): 2554-2594 | DOI: 10.14336/AD.2024.0206
Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis
Lushuang Xie, Qiaofeng Wu, Kelin Li, Mohammed A. S. Khan, Andrew Zhang, Bharati Sinha, Sihui Li, Sulie L. Chang, David L. Brody, Mark W. Grinstaff, Shuanhu Zhou, Gil Alterovitz, Pinghua Liu, Xin Wang
2024, 15 (5): 2168-2190 | DOI: 10.14336/AD.2024.0134
ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis
Ruiyi Yan, Xiao Zhang, Wenlong Xu, Jiayao Li, Yixin Sun, Shengyan Cui, Ran Xu, Wenjing Li, Liqun Jiao, Tao Wang
2025, 16 (1): 250-268 | DOI: 10.14336/AD.2024.0309
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov, Natasha S. Barteneva
2025, 16 (3): 1242-1264 | DOI: 10.14336/AD.2024.0526
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
2025, 16 (2): 917-945 | DOI: 10.14336/AD.2024.0083
Inflammatory Pathogenesis of Post-stroke Depression
Xinyu Feng, Xiaojuan Ma, Juan Li, Qing Zhou, Yao Liu, Jingyi Song, Jiaqi Liu, Qingqing Situ, Lingyue Wang, Jingzhi Zhang, Facai Lin
2025, 16 (1): 209-238 | DOI: 10.14336/AD.2024.0203
Exercise-Induced Central Fatigue: Biomarkers and Non-Medicinal Interventions
Ying Yang, Zhi Feng, Yu-hang Luo, Jue-miao Chen, Yu Zhang, Yi-jun Liao, Hui Jiang, Yinxi Long, Bo Wei
2025, 16 (3): 1302-1315 | DOI: 10.14336/AD.2024.0567
Telomeres: Dysfunction, Maintenance, Aging and Cancer
Pan Liao, Bo Yan, Conglin Wang, Ping Lei
2024, 15 (6): 2595-2631 | DOI: 10.14336/AD.2023.1128
Exploring the Intricate Nexus of Sarcopenia and Cognitive Impairment
Yiwen Xing, Xiaxia Li, Lina Ma
2024, 15 (6): 2334-2344 | DOI: 10.14336/AD.2023.1013
A Potential “Anti-Warburg Effect” in Circulating Tumor Cell-mediated Metastatic Progression?
Zhuofeng Jiang, Jiapeng He, Binyu Zhang, Liping Wang, Chunhao Long, Boxi Zhao, Yufan Yang, Longxiang Du, Weiren Luo, Jianyang Hu, Xin Hong
| DOI: 10.14336/AD.2023.1227
Role of Crosstalk between Glial Cells and Immune Cells in Blood-Brain Barrier Damage and Protection after Acute Ischemic Stroke
Yihui Wang, Wencao Liu, Panpan Geng, Weihong Du, Chun Guo, Qian Wang, Guo-qing Zheng, Xinchun Jin
2024, 15 (6): 2507-2525 | DOI: 10.14336/AD.2023.1010
Therapeutic Potential of Quercetin as an Antioxidant for Bone-Muscle-Tendon Regeneration and Aging
Jae Gyu Kim, Ashish Ranjan Sharma, Yeon-Hee Lee, Srijan Chatterjee, Yean Jung Choi, Roshani Rajvansh, Chiranjib Chakraborty, Sang-Soo Lee
2025, 16 (3): 1414-1437 | DOI: 10.14336/AD.2024.0282
Revisiting Skeletal Muscle Dysfunction and Exercise in Chronic Obstructive Pulmonary Disease: Emerging Significance of Myokines
Lihua Han, Peijun Li, Qinglan He, Chen Yang, Meiling Jiang, Yingqi Wang, Yuanyuan Cao, Xiaoyu Han, Xiaodan Liu, Weibing Wu
2024, 15 (6): 2453-2469 | DOI: 10.14336/AD.2023.1125
Expert consensus on Prospective Precision Diagnosis and Treatment Strategies for Osteoporotic Fractures
Yan Hu, Xiaoqun Li, Xiao Chen, Sicheng Wang, Liehu Cao, Hao Zhang, Yunfei Zhang, Zhiwei Wang, Baoqing Yu, Peijian Tong, Qiang Zhou, Feng Niu, Weiguo Yang, Wencai Zhang, Shijie Chen, Qiang Yang, Tao Shen, Peng Zhang, Yong Zhang, Jun Miao, Haodong Lin, Jinwu Wang, Lei Wang, Xin Ma, Hongjian Liu, Ilia Stambler, Long Bai, Han Liu, Yingying Jing, Guohui Liu, Xinglong Wang, Dongliang Wang, Zhongmin Shi, Robert Chunhua Zhao, Jiacan Su
| DOI: 10.14336/AD.2023.1223
Aging and “Age-Related” Diseases - What Is the Relation?
Wolfgang Kopp
2025, 16 (3): 1316-1346 | DOI: 10.14336/AD.2024.0570
The Expanding Burden of Neurodegenerative Diseases: An Unmet Medical and Social Need
Shu Wang, Yin Jiang, Anchao Yang, Fangang Meng, Jianguo Zhang
| DOI: 10.14336/AD.2024.1071
Irisin: A Potentially Fresh Insight into the Molecular Mechanisms Underlying Vascular Aging
Yinghui Wang, Manying Wang, Yuehui Wang
2024, 15 (6): 2491-2506 | DOI: 10.14336/AD.2023.1112
Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve
Akanksha Salkar, Roshana Vander Wall, Devaraj Basavarajappa, Nitin Chitranshi, Gabriella E. Parilla, Mehdi Mirzaei, Peng Yan, Stuart Graham, Yuyi You
2024, 15 (5): 2069-2083 | DOI: 10.14336/AD.2024.0103
Supplement

1. Supplementary data.pdf (245KB)

Neuroinflammation and Post-Stroke Depression: Focus on the Microglia and Astrocytes
Weizhuo Lu, Jiyue Wen
2025, 16 (1): 394-407 | DOI: 10.14336/AD.2024.0214-1
Association of Plasma Markers of Alzheimer’s Disease, Neurodegeneration, and Neuroinflammation with the Choroid Plexus Integrity in Aging
Mustapha Bouhrara, Keenan A. Walker, Joseph S. R. Alisch, Zhaoyuan Gong, Caio H. Mazucanti, Alexandria Lewis, Abhay R. Moghekar, Lisa Turek, Victoria Collingham, Nader Shehadeh, Giovanna Fantoni, Mary Kaileh, Christopher M. Bergeron, Jan Bergeron, Susan M. Resnick, Josephine M. Egan
2024, 15 (5): 2230-2240 | DOI: 10.14336/AD.2023.1226
Vascular Aging and Atherosclerosis: A Perspective on Aging
Shudong Ma, Xuena Xie, Rong Yuan, Qiqi Xin, Yu Miao, Sean Xiao Leng, Keji Chen, Weihong Cong
2025, 16 (1): 33-48 | DOI: 10.14336/AD.2024.0201-1
Revolutionizing Diabetic Foot Ulcer Care: The Senotherapeutic Approach
Guiqin Zhang, Priyadarshani Nadeeshika Samarawickrama, Li Gui, Yuan Ma, Mei Cao, Hong Zhu, Wei Li, Honglin Yang, Kecheng Li, Yang Yang, Enfang Zhu, Wen Li, Yonghan He
2025, 16 (2): 946-970 | DOI: 10.14336/AD.2024.0065
Isthmin-1 Improves Aging-Related Cardiac Dysfunction in Mice through Enhancing Glycolysis and SIRT1 Deacetylase Activity
Min Hu, Xin Zhang, Yi-Peng Gao, Yu-Xin Hu, Teng Teng, Sha-Sha Wang, Qi-Zhu Tang
2024, 15 (6): 2682-2696 | DOI: 10.14336/AD.2024.0113
Supplement

1. Supplementary data.pdf (2330KB)

Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis
Arubala P. Reddy, Priyanka Rawat, Nicholas Rohr, Razelle Alvir, Jasbir Bisht, Mst Anika Bushra, Jennifer Luong, Aananya P. Reddy
2025, 16 (2): 841-858 | DOI: 10.14336/AD.2024.0328
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies
Yonglian Chen, Jinhui Wu
2025, 16 (2): 1003-1022 | DOI: 10.14336/AD.2024.0407
Polypharmacological Potential of Phosphodiesterase 5 Inhibitors for the Treatment of Neurocognitive Disorders
Ashish Kumar, Fred Kim, Dong-Keun Song, Jai Jun Choung
2024, 15 (5): 2008-2014 | DOI: 10.14336/AD.2023.1129
Multi-Trajectories of Intrinsic Capacity Decline and Their Impact on Age-Related Outcomes: A 20-Year National Longitudinal Cohort Study
Lin-Chieh Meng, Hui-Min Chuang, Wan-Hsuan Lu, Wei-Ju Lee, Chih-Kuang Liang, Ching-Hui Loh, Fei-Yuan Hsiao, Liang-Kung Chen
2024, 15 (6): 2697-2709 | DOI: 10.14336/AD.2023.1115-1
Involvement of Inheritance in Determining Telomere Length beyond Environmental and Lifestyle Factors
Naheemat Modupeola Gold, Michael Ngozi Okeke, Yonghan He
2024, 15 (6): 2470-2490 | DOI: 10.14336/AD.2023.1023
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke
Xiaosong He, Xin Wang, Hui Wang, Tao Wang, Fuhan Yang, Yuchen Chen, Zifei Pei, Yuting Bai, Wen Li, Zheng Wu, Gong Chen
2024, 15 (6): 2632-2649 | DOI: 10.14336/AD.2023.1213
Supplement

1. Supplementary data.pdf (1075KB)

Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions
Xiang-Chun Huang, Yi-Nan Jiang, Hai-Juan Bao, Jie-Lin Wang, Rong-Jin Lin, Jing Yuan, Jing-Yuan Xian, Yang Zhao, Shuo Chen
2025, 16 (1): 146-167 | DOI: 10.14336/AD.2024.0126
Physical Exercise Counteracts Aging-Associated White Matter Demyelination Causing Cognitive Decline
Tanya H. Butt, Makoto Tobiume, Diane B. Re, Shingo Kariya
2024, 15 (5): 2136-2148 | DOI: 10.14336/AD.2024.0216
Choroid Plexus Volume, Amyloid Burden, and Cognition in the Alzheimer’s Disease Continuum
Seong Ho Jeong, Chae Jung Park, Jungho Cha, Sang-Young Kim, Seung-Koo Lee, Yun Joong Kim, Young H. Sohn, Seok Jong Chung, Phil Hyu Lee
2025, 16 (1): 552-564 | DOI: 10.14336/AD.2024.0118
Immunological Landscape of Retinal Ischemia-Reperfusion Injury: Insights into Resident and Peripheral Immune Cell Responses
Shan He, Cuiying Liu, Changhong Ren, Heng Zhao, Xuxiang Zhang
2025, 16 (1): 115-136 | DOI: 10.14336/AD.2024.0129
Senescent T Cells in Age-Related Diseases
Pei-Jie Yu, Mei Zhou, Yan Liu, Jie Du
2025, 16 (1): 321-344 | DOI: 10.14336/AD.2024.0219