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2024
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Total 40 results are found
Age-Related Dysfunction in Balance: A Comprehensive Review of Causes, Consequences, and Interventions
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
2025, 16 (2): 714-737 | DOI: 10.14336/AD.2024.0124-1
Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
Qianting Deng, Chongyun Wu, Emily Parker, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
2024, 15 (4): 1537-1564 | DOI: 10.14336/AD.2023.0907
Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Sajid Ur Rahman, Abdul Qadeer, Ziyun Wu
2024, 15 (2): 565-583 | DOI: 10.14336/AD.2023.0519-1
Consequences of Aging on Bone
Lingli Zhang, Qiao Guan, Zhikun Wang, Jie Feng, Jun Zou, Bo Gao
2024, 15 (6): 2417-2452 | DOI: 10.14336/AD.2023.1115
Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
2025, 16 (2): 980-1002 | DOI: 10.14336/AD.2024.0331
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
2024, 15 (2): 445-448 | DOI: 10.14336/AD.2023.0707-1
Supplement

1. Supplementary data.pdf (2374KB)

Glycometabolic Reprogramming of Microglia in Neurodegenerative Diseases: Insights from Neuroinflammation
Qi Huang, Yanfu Wang, Shanshan Chen, Fengxia Liang
2024, 15 (3): 1155-1175 | DOI: 10.14336/AD.2023.0807
Exercise-Induced Central Fatigue: Biomarkers and Non-Medicinal Interventions
Ying Yang, Zhi Feng, Yu-hang Luo, Jue-miao Chen, Yu Zhang, Yi-jun Liao, Hui Jiang, Yinxi Long, Bo Wei
2025, 16 (3): 1302-1315 | DOI: 10.14336/AD.2024.0567
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training
Daniel G. Blackmore, Mia A. Schaumberg, Maryam Ziaei, Samuel Belford, Xuan Vinh To, Imogen O’Keeffe, Anne Bernard, Jules Mitchell, Emily Hume, Grace L. Rose, Thomas Shaw, Ashley York, Markus Barth, Elizabeth J. Cooper, Tina L. Skinner, Fatima Nasrallah, Stephan Riek, Perry F. Bartlett
2025, 16 (3): 1732-1754 | DOI: 10.14336/AD.2024.0642
Supplement

1. Supplementary data.pdf (6754KB)

ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis
Ruiyi Yan, Xiao Zhang, Wenlong Xu, Jiayao Li, Yixin Sun, Shengyan Cui, Ran Xu, Wenjing Li, Liqun Jiao, Tao Wang
2025, 16 (1): 250-268 | DOI: 10.14336/AD.2024.0309
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies
Liyao Zheng, Shipei He, Hong Wang, Jinling Li, Yuanyuan Liu, Sijia Liu
2024, 15 (6): 2554-2594 | DOI: 10.14336/AD.2024.0206
Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43
Jianxing Song
2024, 15 (5): 2084-2112 | DOI: 10.14336/AD.2023.1118
Cerebral Small Vessel Disease: Current and Emerging Therapeutic Strategies
Yuewen Sun, Xiaoqian Song, Chenyang Jin, Yilong Peng, Jing Zhou, Xueping Zheng
2026, 17 (1): 286-303 | DOI: 10.14336/AD.2024.1515
Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis
Lushuang Xie, Qiaofeng Wu, Kelin Li, Mohammed A. S. Khan, Andrew Zhang, Bharati Sinha, Sihui Li, Sulie L. Chang, David L. Brody, Mark W. Grinstaff, Shuanhu Zhou, Gil Alterovitz, Pinghua Liu, Xin Wang
2024, 15 (5): 2168-2190 | DOI: 10.14336/AD.2024.0134
State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease
Elizabeth M Rhea, Manon Leclerc, Hussein N Yassine, Ana W Capuano, Han Tong, Vladislav A Petyuk, Shannon L Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis
2024, 15 (4): 1688-1725 | DOI: 10.14336/AD.2023.0814
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
2025, 16 (2): 917-945 | DOI: 10.14336/AD.2024.0083
The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds
Wenjie He, Ming Tang, Rifang Gu, Xingqian Wu, Xinrui Mu, Xuqiang Nie
2025, 16 (1): 373-393 | DOI: 10.14336/AD.2024.0212
Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function
Xiaodan Liu, Giuseppe Barisano, Xingfeng Shao, Kay Jann, John M Ringman, Hanzhang Lu, Konstantinos Arfanakis, Arvind Caprihan, Charles DeCarli, Brian T Gold, Pauline Maillard, Claudia L Satizabal, Elyas Fadaee, Mohamad Habes, Lara Stables, Herpreet Singh, Bruce Fischl, Andre van der Kouwe, Kristin Schwab, Karl G Helmer, Steven M Greenberg, Danny J.J Wang, for the MarkVCID Consortium
2024, 15 (4): 1885-1898 | DOI: 10.14336/AD.2023.0321-2
The Expanding Burden of Neurodegenerative Diseases: An Unmet Medical and Social Need
Shu Wang, Yin Jiang, Anchao Yang, Fangang Meng, Jianguo Zhang
2025, 16 (5): 2937-2952 | DOI: 10.14336/AD.2024.1071
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway
Ruoyan Xue, Mengyao Xie, Zhiyuan Wu, Shu Wang, Yongli Zhang, Zhijin Han, Chen Li, Qi Tang, Liping Wang, Di Li, Shihua Wang, Hua Yang, Robert Chunhua Zhao
2024, 15 (2): 851-868 | DOI: 10.14336/AD.2023.0719-1
Supplement

1. Supplementary data.pdf (505KB)

Mitochondria: A Potential Rejuvenation Tool against Aging
Qian Hua Phua, Shi Yan Ng, Boon-Seng Soh
2024, 15 (2): 503-516 | DOI: 10.14336/AD.2023.0712
Therapeutic Potential of Quercetin as an Antioxidant for Bone-Muscle-Tendon Regeneration and Aging
Jae Gyu Kim, Ashish Ranjan Sharma, Yeon-Hee Lee, Srijan Chatterjee, Yean Jung Choi, Roshani Rajvansh, Chiranjib Chakraborty, Sang-Soo Lee
2025, 16 (3): 1414-1437 | DOI: 10.14336/AD.2024.0282
Arterial Aging and Cerebrovascular Function: Impact of Aerobic Exercise Training in Older Adults
Tsubasa Tomoto, Rong Zhang
2024, 15 (4): 1672-1687 | DOI: 10.14336/AD.2023.1109-1
Inflammatory Pathogenesis of Post-stroke Depression
Xinyu Feng, Xiaojuan Ma, Juan Li, Qing Zhou, Yao Liu, Jingyi Song, Jiaqi Liu, Qingqing Situ, Lingyue Wang, Jingzhi Zhang, Facai Lin
2025, 16 (1): 209-238 | DOI: 10.14336/AD.2024.0203
Perspectives on Osteoarthritis Treatment with Mesenchymal Stem Cells and Radix Achyranthis Bidentatae
Xingyan An, Jiao Wang, Ke Xu, Robert Chunhua Zhao, Jiacan Su
2024, 15 (3): 1029-1045 | DOI: 10.14336/AD.2023.0817
Aging and “Age-Related” Diseases - What Is the Relation?
Wolfgang Kopp
2025, 16 (3): 1316-1346 | DOI: 10.14336/AD.2024.0570
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov, Natasha S. Barteneva
2025, 16 (3): 1242-1264 | DOI: 10.14336/AD.2024.0526
Aging, Cellular Senescence, and Glaucoma
Yumeng Zhang, Shouyue Huang, Bing Xie, Yisheng Zhong
2024, 15 (2): 546-564 | DOI: 10.14336/AD.2023.0630-1
Telomeres: Dysfunction, Maintenance, Aging and Cancer
Pan Liao, Bo Yan, Conglin Wang, Ping Lei
2024, 15 (6): 2595-2631 | DOI: 10.14336/AD.2023.1128
Exploring the Intricate Nexus of Sarcopenia and Cognitive Impairment
Yiwen Xing, Xiaxia Li, Lina Ma
2024, 15 (6): 2334-2344 | DOI: 10.14336/AD.2023.1013
Farnesoid X receptor: From Structure to Function and Its Pharmacology in Liver Fibrosis
Chuan Ding, Zeping Wang, Xinyue Dou, Qiao Yang, Yan Ning, Shi Kao, Xianan Sang, Min Hao, Kuilong Wang, Mengyun Peng, Shuosheng Zhang, Xin Han, Gang Cao
2024, 15 (4): 1508-1536 | DOI: 10.14336/AD.2023.0830
The Emerging Role of the Mitochondrial Respiratory Chain in Skeletal Aging
Huaqiang Tao, Pengfei Zhu, Wenyu Xia, Miao Chu, Kai Chen, Qiufei Wang, Ye Gu, Xiaomin Lu, Jiaxiang Bai, Dechun Geng
2024, 15 (4): 1784-1812 | DOI: 10.14336/AD.2023.0924
Revisiting Skeletal Muscle Dysfunction and Exercise in Chronic Obstructive Pulmonary Disease: Emerging Significance of Myokines
Lihua Han, Peijun Li, Qinglan He, Chen Yang, Meiling Jiang, Yingqi Wang, Yuanyuan Cao, Xiaoyu Han, Xiaodan Liu, Weibing Wu
2024, 15 (6): 2453-2469 | DOI: 10.14336/AD.2023.1125
The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Yang Yu, Ran Chen, Kaiyue Mao, Maoyan Deng, Zhigang Li
2024, 15 (2): 459-479 | DOI: 10.14336/AD.2023.0718
Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation
Yu Chen, Junren Chen, Ziwei Xing, Cheng Peng, Dan Li
2024, 15 (2): 739-754 | DOI: 10.14336/AD.2023.0718-1
Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential
Linkai Qu, Yanwei Li, Fan Liu, Yimeng Fang, Jiaxuan He, Jiahui Ma, Ting Xu, Lei Wang, Pengyu Lei, Hao Dong, Libo Jin, Qinsi Yang, Wei Wu, Da Sun
2024, 15 (3): 1108-1131 | DOI: 10.14336/AD.2023.0823-2
Role of Crosstalk between Glial Cells and Immune Cells in Blood-Brain Barrier Damage and Protection after Acute Ischemic Stroke
Yihui Wang, Wencao Liu, Panpan Geng, Weihong Du, Chun Guo, Qian Wang, Guo-qing Zheng, Xinchun Jin
2024, 15 (6): 2507-2525 | DOI: 10.14336/AD.2023.1010
Mitochondria-mediated Ferroptosis in Diseases Therapy: From Molecular Mechanisms to Implications
Fuhai Feng, Shasha He, Xiaoling Li, Jiake He, Lianxiang Luo
2024, 15 (2): 714-738 | DOI: 10.14336/AD.2023.0717
Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia
Wenze Deng, Pengcheng Yi, Yanhong Xiong, Jun Ying, Yue Lin, Yao Dong, Gen Wei, Xifeng Wang, Fuzhou Hua
2024, 15 (2): 480-502 | DOI: 10.14336/AD.2023.0727
Vascular Aging and Atherosclerosis: A Perspective on Aging
Shudong Ma, Xuena Xie, Rong Yuan, Qiqi Xin, Yu Miao, Sean Xiao Leng, Keji Chen, Weihong Cong
2025, 16 (1): 33-48 | DOI: 10.14336/AD.2024.0201-1