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Total 40 results are found
Human Aging and Age-Related Diseases: From Underlying Mechanisms to Pro-Longevity Interventions
Piotr Paweł Chmielewski, Krzysztof Data, Bartłomiej Strzelec, Maryam Farzaneh, Amir Anbiyaiee, Uzma Zaheer, Shahab Uddin, Mohadeseh Sheykhi-Sabzehpoush, Paul Mozdziak, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempisty
| DOI: 10.14336/AD.2024.0280
Age-Related Dysfunction in Balance: A Comprehensive Review of Causes, Consequences, and Interventions
Jixian Wang, Yongfang Li, Guo-Yuan Yang, Kunlin Jin
2025, 16 (2): 714-737 | DOI: 10.14336/AD.2024.0124-1
Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause
Wendi Pei, Xiaomin Cao, Puyao Zhang, Lin Fu, Ping Zhou, Ye Liu, Yong Fan, Fengqin Xu, Canhui Cao, Yang Yu
2024, 15 (2): 445-448 | DOI: 10.14336/AD.2023.0707-1
Supplement

1. Supplementary data.pdf (2374KB)

Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging
Sajid Ur Rahman, Abdul Qadeer, Ziyun Wu
2024, 15 (2): 565-583 | DOI: 10.14336/AD.2023.0519-1
Microglia and Astrocytes in Alzheimer’s Disease: Significance and Summary of Recent Advances
Qianting Deng, Chongyun Wu, Emily Parker, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
2024, 15 (4): 1537-1564 | DOI: 10.14336/AD.2023.0907
Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses
Mohammad Nasb, Weichu Tao, Ning Chen
2024, 15 (1): 43-73 | DOI: 10.14336/AD.2023.0608
Hypoxia and the Aging Cardiovascular System
Antoine Raberin, Johannes Burtscher, Martin Burtscher, Grégoire P. Millet
2023, 14 (6): 2051-2070 | DOI: 10.14336/AD.2023.0424
Consequences of Aging on Bone
Lingli Zhang, Qiao Guan, Zhikun Wang, Jie Feng, Jun Zou, Bo Gao
2024, 15 (6): 2417-2452 | DOI: 10.14336/AD.2023.1115
Aging Gut Microbiome in Healthy and Unhealthy Aging
Yangyanqiu Wang, Zhanbo Qu, Jian Chu, Shuwen Han
2025, 16 (2): 980-1002 | DOI: 10.14336/AD.2024.0331
Post-Stroke Neuropsychiatric Complications: Types, Pathogenesis, and Therapeutic Intervention
Jing Zhou, Yijia Fangma, Zhong Chen, Yanrong Zheng
2023, 14 (6): 2127-2152 | DOI: 10.14336/AD.2023.0310-2
Glycometabolic Reprogramming of Microglia in Neurodegenerative Diseases: Insights from Neuroinflammation
Qi Huang, Yanfu Wang, Shanshan Chen, Fengxia Liang
2024, 15 (3): 1155-1175 | DOI: 10.14336/AD.2023.0807
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training
Daniel G. Blackmore, Mia A. Schaumberg, Maryam Ziaei, Samuel Belford, Xuan Vinh To, Imogen O’Keeffe, Anne Bernard, Jules Mitchell, Emily Hume, Grace L. Rose, Thomas Shaw, Ashley York, Markus Barth, Elizabeth J. Cooper, Tina L. Skinner, Fatima Nasrallah, Stephan Riek, Perry F. Bartlett
2025, 16 (3): 1732-1754 | DOI: 10.14336/AD.2024.0642
Supplement

1. Supplementary data.pdf (6754KB)

Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43
Jianxing Song
2024, 15 (5): 2084-2112 | DOI: 10.14336/AD.2023.1118
TGF-β as A Master Regulator of Aging-Associated Tissue Fibrosis
Li-Li Ren, Hua Miao, Yan-Ni Wang, Fei Liu, Ping Li, Ying-Yong Zhao
2023, 14 (5): 1633-1650 | DOI: 10.14336/AD.2023.0222
The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds
Wenjie He, Ming Tang, Rifang Gu, Xingqian Wu, Xinrui Mu, Xuqiang Nie
2025, 16 (1): 373-393 | DOI: 10.14336/AD.2024.0212
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies
Liyao Zheng, Shipei He, Hong Wang, Jinling Li, Yuanyuan Liu, Sijia Liu
2024, 15 (6): 2554-2594 | DOI: 10.14336/AD.2024.0206
Tryptophan Metabolism in Alzheimer’s Disease with the Involvement of Microglia and Astrocyte Crosstalk and Gut-Brain Axis
Lushuang Xie, Qiaofeng Wu, Kelin Li, Mohammed A. S. Khan, Andrew Zhang, Bharati Sinha, Sihui Li, Sulie L. Chang, David L. Brody, Mark W. Grinstaff, Shuanhu Zhou, Gil Alterovitz, Pinghua Liu, Xin Wang
2024, 15 (5): 2168-2190 | DOI: 10.14336/AD.2024.0134
Arterial Aging and Cerebrovascular Function: Impact of Aerobic Exercise Training in Older Adults
Tsubasa Tomoto, Rong Zhang
2024, 15 (4): 1672-1687 | DOI: 10.14336/AD.2023.1109-1
Mitochondria: A Potential Rejuvenation Tool against Aging
Qian Hua Phua, Shi Yan Ng, Boon-Seng Soh
2024, 15 (2): 503-516 | DOI: 10.14336/AD.2023.0712
State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer’s Disease
Elizabeth M Rhea, Manon Leclerc, Hussein N Yassine, Ana W Capuano, Han Tong, Vladislav A Petyuk, Shannon L Macauley, Xavier Fioramonti, Owen Carmichael, Frederic Calon, Zoe Arvanitakis
2024, 15 (4): 1688-1725 | DOI: 10.14336/AD.2023.0814
Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function
Xiaodan Liu, Giuseppe Barisano, Xingfeng Shao, Kay Jann, John M Ringman, Hanzhang Lu, Konstantinos Arfanakis, Arvind Caprihan, Charles DeCarli, Brian T Gold, Pauline Maillard, Claudia L Satizabal, Elyas Fadaee, Mohamad Habes, Lara Stables, Herpreet Singh, Bruce Fischl, Andre van der Kouwe, Kristin Schwab, Karl G Helmer, Steven M Greenberg, Danny J.J Wang, for the MarkVCID Consortium
2024, 15 (4): 1885-1898 | DOI: 10.14336/AD.2023.0321-2
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway
Ruoyan Xue, Mengyao Xie, Zhiyuan Wu, Shu Wang, Yongli Zhang, Zhijin Han, Chen Li, Qi Tang, Liping Wang, Di Li, Shihua Wang, Hua Yang, Robert Chunhua Zhao
2024, 15 (2): 851-868 | DOI: 10.14336/AD.2023.0719-1
Supplement

1. Supplementary data.pdf (505KB)

Perspectives on Osteoarthritis Treatment with Mesenchymal Stem Cells and Radix Achyranthis Bidentatae
Xingyan An, Jiao Wang, Ke Xu, Robert Chunhua Zhao, Jiacan Su
2024, 15 (3): 1029-1045 | DOI: 10.14336/AD.2023.0817
The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms
Yang Yu, Ran Chen, Kaiyue Mao, Maoyan Deng, Zhigang Li
2024, 15 (2): 459-479 | DOI: 10.14336/AD.2023.0718
The Emerging Role of Interleukin-(IL)-11/IL-11R in Bone Metabolism and Homeostasis: From Cytokine to Osteokine
Bingzi Dong, Jingjing Zhu, Xian Chen, Hongyuan Jiang, Yujie Deng, Lili Xu, Yangang Wang, Shufa Li
2023, 14 (6): 2113-2126 | DOI: 10.14336/AD.2023.0306
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Dmitry S. Prudinnik, Aigul Kussanova, Ivan A. Vorobjev, Alexander Tikhonov, Fazly I. Ataullakhanov, Natasha S. Barteneva
2025, 16 (3): 1242-1264 | DOI: 10.14336/AD.2024.0526
ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis
Ruiyi Yan, Xiao Zhang, Wenlong Xu, Jiayao Li, Yixin Sun, Shengyan Cui, Ran Xu, Wenjing Li, Liqun Jiao, Tao Wang
2025, 16 (1): 250-268 | DOI: 10.14336/AD.2024.0309
The Role of cGAS-STING in Age-Related Diseases from Mechanisms to Therapies
Weitao Zheng, Dechao Feng, Xingyu Xiong, Xinyang Liao, Sheng Wang, Hang Xu, Weizhen Le, Qiang Wei, Lu Yang
2023, 14 (4): 1145-1165 | DOI: 10.14336/AD.2023.0117
Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation
Yu Chen, Junren Chen, Ziwei Xing, Cheng Peng, Dan Li
2024, 15 (2): 739-754 | DOI: 10.14336/AD.2023.0718-1
Telomeres: Dysfunction, Maintenance, Aging and Cancer
Pan Liao, Bo Yan, Conglin Wang, Ping Lei
2024, 15 (6): 2595-2631 | DOI: 10.14336/AD.2023.1128
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications
Qiuyang Gu, Yumei An, Mingyuan Xu, Xinqi Huang, Xueshi Chen, Xianzhe Li, Haiyan Shan, Mingyang Zhang
2025, 16 (2): 917-945 | DOI: 10.14336/AD.2024.0083
Inflammatory Pathogenesis of Post-stroke Depression
Xinyu Feng, Xiaojuan Ma, Juan Li, Qing Zhou, Yao Liu, Jingyi Song, Jiaqi Liu, Qingqing Situ, Lingyue Wang, Jingzhi Zhang, Facai Lin
2025, 16 (1): 209-238 | DOI: 10.14336/AD.2024.0203
Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential
Linkai Qu, Yanwei Li, Fan Liu, Yimeng Fang, Jiaxuan He, Jiahui Ma, Ting Xu, Lei Wang, Pengyu Lei, Hao Dong, Libo Jin, Qinsi Yang, Wei Wu, Da Sun
2024, 15 (3): 1108-1131 | DOI: 10.14336/AD.2023.0823-2
The Emerging Role of the Mitochondrial Respiratory Chain in Skeletal Aging
Huaqiang Tao, Pengfei Zhu, Wenyu Xia, Miao Chu, Kai Chen, Qiufei Wang, Ye Gu, Xiaomin Lu, Jiaxiang Bai, Dechun Geng
2024, 15 (4): 1784-1812 | DOI: 10.14336/AD.2023.0924
Mitochondria-mediated Ferroptosis in Diseases Therapy: From Molecular Mechanisms to Implications
Fuhai Feng, Shasha He, Xiaoling Li, Jiake He, Lianxiang Luo
2024, 15 (2): 714-738 | DOI: 10.14336/AD.2023.0717
Exercise-Induced Central Fatigue: Biomarkers and Non-Medicinal Interventions
Ying Yang, Zhi Feng, Yu-hang Luo, Jue-miao Chen, Yu Zhang, Yi-jun Liao, Hui Jiang, Yinxi Long, Bo Wei
2025, 16 (3): 1302-1315 | DOI: 10.14336/AD.2024.0567
Exploring the Intricate Nexus of Sarcopenia and Cognitive Impairment
Yiwen Xing, Xiaxia Li, Lina Ma
2024, 15 (6): 2334-2344 | DOI: 10.14336/AD.2023.1013
Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia
Wenze Deng, Pengcheng Yi, Yanhong Xiong, Jun Ying, Yue Lin, Yao Dong, Gen Wei, Xifeng Wang, Fuzhou Hua
2024, 15 (2): 480-502 | DOI: 10.14336/AD.2023.0727
A Potential “Anti-Warburg Effect” in Circulating Tumor Cell-mediated Metastatic Progression?
Zhuofeng Jiang, Jiapeng He, Binyu Zhang, Liping Wang, Chunhao Long, Boxi Zhao, Yufan Yang, Longxiang Du, Weiren Luo, Jianyang Hu, Xin Hong
| DOI: 10.14336/AD.2023.1227
Lactylation: An Innovative Approach to Disease Control
Xiaoxin Jiang, Yanyan Yang, Xiaolu Li, Tianxiang Li, Tao Yu, Xiuxiu Fu
| DOI: 10.14336/AD.2024.0918