Aging and disease

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Total 40 results are found

Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination Sankha Shubhra Chakrabarti, Ashutosh Tiwari, Sumit Jaiswal, Upinder Kaur, Ishan Kumar, Amit Mittal, Anup Singh, Kunlin Jin, Sasanka Chakrabarti: 2022, 13 (3): 633-636 | DOI: 10.14336/AD.2021.1102; PDF (363KB)

Metabolic Strategies in Healthcare: A New Era Matthew CL Phillips: 2022, 13 (3): 655-672 | DOI: 10.14336/AD.2021.1018; PDF (855KB)

New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases Yu-Qing Ni, You-Shuo Liu: 2021, 12 (8): 1948-1963 | DOI: 10.14336/AD.2021.0603; PDF (645KB)

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors Jing She, Rui Sheng, Zheng-Hong Qin: 2021, 12 (8): 1879-1897 | DOI: 10.14336/AD.2021.0523; PDF (621KB)

Effects of Ketogenic Diet on Neuroinflammation in Neurodegenerative Diseases Ziying Jiang, Xi Yin, Miao Wang, Tong Chen, Yuanyuan Wang, Zhongbao Gao, Zhenfu Wang: 2022, 13 (4): 1146-1165 | DOI: 10.14336/AD.2021.1217; PDF (808KB)

Depression and Dementia in Older Adults: A Neuropsychological Review Syuichi Tetsuka: 2021, 12 (8): 1920-1934 | DOI: 10.14336/AD.2021.0526; PDF (543KB)

Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives Juan Liu, Yuzhu Tan, Hao Cheng, Dandan Zhang, Wuwen Feng, Cheng Peng: 2022, 13 (4): 1106-1126 | DOI: 10.14336/AD.2022.0104; PDF (1455KB)

Identifying Dynamic Patterns of Polypharmacy for Patients with Dementia from Primary Care Electronic Health Records: A Machine Learning Driven Longitudinal Study Elisabetta Longo, Bruce Burnett, Sarah Bauermeister, Shang-Ming Zhou: | DOI: 10.14336/AD.2022.0829; PDF (730KB)
Supplement; 1. Supplementary data.pdf (1432KB)

A Unique Type of Highly-Activated Microglia Evoking Brain Inflammation via Mif/Cd74 Signaling Axis in Aged Mice Chenghao Jin, Yijie Shao, Xiaotao Zhang, Jiani Xiang, Ruize Zhang, Zeyu Sun, Shuhao Mei, Jingyi Zhou, Jianmin Zhang, Ligen Shi: 2021, 12 (8): 2125-2139 | DOI: 10.14336/AD.2021.0520; PDF (2051KB)
Supplement; 1. Supplementary data.pdf (1992KB)

The Effect of COVID-19-related Lockdowns on Diet and Physical Activity in Older Adults: A Systematic Review Elisabeth Anne Larson, Karlen Stade Bader-Larsen, Faidon Magkos: 2021, 12 (8): 1935-1947 | DOI: 10.14336/AD.2021.0606; PDF (772KB)

Pathogeneses and Imaging Features of Cerebral White Matter Lesions of Vascular Origins Xiaoqin Wu, Jingyuan Ya, Da Zhou, Yuchuan Ding, Xunming Ji, Ran Meng: 2021, 12 (8): 2031-2051 | DOI: 10.14336/AD.2021.0414; PDF (1249KB)

Extension of the Life Span by Acarbose: Is It Mediated by the Gut Microbiota? Baiyun Wu, Jiai Yan, Ju Yang, Yanping Xia, Dan Li, Feng Zhang, Hong Cao: 2022, 13 (4): 1005-1014 | DOI: 10.14336/AD.2022.0117; PDF (535KB)

Blocking C3d⁺/GFAP⁺ A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke Qi Zhang, Chang Liu, Rubing Shi, Shiyi Zhou, Huimin Shan, Lidong Deng, Tingting Chen, Yiyan Guo, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang, Yaohui Tang: 2022, 13 (3): 943-959 | DOI: 10.14336/AD.2021.1029; PDF (1915KB)
Supplement; 1. Supplementary data.pdf (888KB)

Mechanisms of Short-Chain Fatty Acids Derived from Gut Microbiota in Alzheimer's Disease Xiao-hang Qian, Ru-yan Xie, Xiao-li Liu, Sheng-di Chen, Hui-dong Tang: 2022, 13 (4): 1252-1266 | DOI: 10.14336/AD.2021.1215; PDF (642KB)

Intrinsic Capacity in Older Adults: Recent Advances Yaru Zhou, Lina Ma: 2022, 13 (2): 353-359 | DOI: 10.14336/AD.2021.0818; PDF (361KB)

SIRT6 in Vascular Diseases, from Bench to Bedside Si-Chong Ren, Xiangqi Chen, Hui Gong, Han Wang, Chuan Wu, Pei-Heng Li, Xiao-Feng Chen, Jia-Hua Qu, Xiaoqiang Tang: 2022, 13 (4): 1015-1029 | DOI: 10.14336/AD.2021.1204; PDF (1325KB)

Vascular Calcification in Chronic Kidney Disease: An Update and Perspective Si-Chong Ren, Nan Mao, Si Yi, Xin Ma, Jia-Qiong Zou, Xiaoqiang Tang, Jun-Ming Fan: 2022, 13 (3): 673-697 | DOI: 10.14336/AD.2021.1024; PDF (1225KB)

Three Outbreaks of COVID-19 in a Single Nursing Home over Two Years of the SARS-CoV-2 Pandemic Vladan Čokić, Zorana Popovska, Olivera Lijeskić, Ljiljana Šabić, Olgica Djurković-Djaković: 2023, 14 (1): 99-111 | DOI: 10.14336/AD.2022.0624; PDF (821KB)

The Role of Kynurenine Pathway and NAD⁺ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Mona Dehhaghi, Hamed Kazemi Shariat Panahi, Bahar Kavyani, Benjamin Heng, Vanessa Tan, Nady Braidy, Gilles J. Guillemin: 2022, 13 (3): 698-711 | DOI: 10.14336/AD.2021.0824; PDF (807KB)

Skeletal Muscle Metabolic Alternation Develops Sarcopenia Qiumei Yang, Piu Chan: 2022, 13 (3): 801-814 | DOI: 10.14336/AD.2021.1107; PDF (698KB)

COVID-19 Pandemic and Osteoporosis in Elderly Patients Jun Tang: 2022, 13 (4): 960-969 | DOI: 10.14336/AD.2021.1201; PDF (418KB)

SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases Zhenyang Guo, Peng Li, Junbo Ge, Hua Li: 2022, 13 (6): 1787-1822 | DOI: 10.14336/AD.2022.0413; PDF (2013KB)
Supplement; 1. Supplementary data.pdf (527KB)

Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells Chiara de Lucia, Tytus Murphy, Aleksandra Maruszak, Paul Wright, Timothy R Powell, Naomi Hartopp, Simone de Jong, Michael J O'Sullivan, Gerome Breen, Jack Price, Simon Lovestone, Sandrine Thuret: 2021, 12 (8): 2151-2172 | DOI: 10.14336/AD.2021.0409; PDF (1600KB)
Supplement; 1. Supplementary data.pdf (1416KB)

The safety and efficacy of Ezetimibe Plus Statins on ASVD and Related Diseases Shuling Wan, Yuchuan Ding, Xunming Ji, Ran Meng: 2021, 12 (8): 1857-1871 | DOI: 10.14336/AD.2021.0412; PDF (604KB)

Single-Cell RNA-Seq Reveals a Population of Smooth Muscle Cells Responsible for Atherogenesis Xiaofeng Shi, Shangming Zhu, Meijing Liu, Sara Saymuah Stone, Yao Rong, Ke Mao, Xiaopeng Xu, Chao Ma, Zhuoyuan Jiang, Yan Zha, Chun Yan, Xiaofan Yu, Di Wu, Guiyou Liu, Jidong Mi, Jianping Zhao, Yuan Li, Yuchuan Ding, Xiaogang Wang, Yong-Biao Zhang, Xunming Ji: 2022, 13 (6): 1939-1953 | DOI: 10.14336/AD.2022.0313; PDF (1594KB)

Melatonin as an Antioxidant Agent in Stroke: An Updated Review Junjie Wang, Shiqi Gao, Cameron Lenahan, Yichen Gu, Xiaoyu Wang, Yuanjian Fang, Weilin Xu, Haijian Wu, Yuanbo Pan, Anwen Shao, Jianmin Zhang: 2022, 13 (6): 1823-1844 | DOI: 10.14336/AD.2022.0405; PDF (679KB)

Stem Cell Transplantation for Parkinson’s Disease: Current Challenges and Perspectives Xinlin Zeng, Hua Qin: 2022, 13 (6): 1652-1663 | DOI: 10.14336/AD.2022.0312; PDF (573KB)

Mitochondrial Quality Control in Sarcopenia: Updated Overview of Mechanisms and Interventions Di Liu, Yi-bin Fan, Xiao-hua Tao, Wei-li Pan, Yu-xiang Wu, Xiu-hua Wang, Yu-qiong He, Wen-feng Xiao, Yu-sheng Li: 2021, 12 (8): 2016-2030 | DOI: 10.14336/AD.2021.0427; PDF (565KB)

Effect Of Exercise on Muscle Mass, Fat Mass, Bone Mass, Muscular Strength and Physical Performance in Community Dwelling Older Adults: Systematic Review and Meta-Analysis Alejandra González-Rocha, Lucia Mendez-Sanchez, María Araceli Ortíz-Rodríguez, Edgar Denova-Gutiérrez: 2022, 13 (5): 1421-1435 | DOI: 10.14336/AD.2022.0215; PDF (1149KB)
Supplement; 1. Supplementary data.pdf (960KB)

Cell Heterogeneity Uncovered by Single-Cell RNA Sequencing Offers Potential Therapeutic Targets for Ischemic Stroke Min Qiu, Jia-bin Zong, Quan-wei He, Yu-xiao Liu, Yan Wan, Man Li, Yi-fan Zhou, Jie-hong Wu, Bo Hu: 2022, 13 (5): 1436-1454 | DOI: 10.14336/AD.2022.0212; PDF (970KB)

ACE2 and COVID-19 Susceptibility and Severity Ming Zheng: 2022, 13 (2): 360-372 | DOI: 10.14336/AD.2021.0805; PDF (1806KB)

Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity Cyril Statzer, Ji Young Cecilia Park, Collin Y. Ewald: | DOI: 10.14336/AD.2022.1116; PDF (1125KB)

Dysfunction of the Blood-brain Barrier in Cerebral Microbleeds: from Bedside to Bench Hai-ling Wang, Chun-lin Zhang, Yan-mei Qiu, An-qi Chen, Ya-nan Li, Bo Hu: 2021, 12 (8): 1898-1919 | DOI: 10.14336/AD.2021.0514; PDF (798KB)

The Applications of Focused Ultrasound (FUS) in Alzheimer’s Disease Treatment: A Systematic Review on Both Animal and Human Studies Xiaodan Liu, S. Sta Maria Naomi, Wu Lin Sharon, E. Jacobs Russell: 2021, 12 (8): 1977-2002 | DOI: 10.14336/AD.2021.0510; PDF (751KB)

Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant Response Xiaogang Chu, Kumar Subramani, Bobby Thomas, Alvin V Terry, Sadanand Fulzele, Raghavan Pillai Raju: 2022, 13 (2): 568-582 | DOI: 10.14336/AD.2021.0830; PDF (1934KB)

Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging Shuo Zhang, Neng Zhu, Jia Gu, Hong-Fang Li, Yun Qiu, Duan-Fang Liao, Li Qin: 2022, 13 (4): 1042-1055 | DOI: 10.14336/AD.2022.0116; PDF (637KB)

MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis Yanhui Cui, Xueqin Wang, Fengyu Lin, Wen Li, Yuhao Zhao, Fei Zhu, Hang Yang, Mingjun Rao, Yi li, Huaying Liang, Minhui Dai, Ben Liu, Lingli Chen, Duoduo Han, Rongli Lu, Wenzhong Peng, Yan Zhang, Chao Song, Yanwei Luo, Pinhua Pan: 2022, 13 (3): 899-909 | DOI: 10.14336/AD.2021.1023; PDF (1271KB)
Supplement; 1. Supplementary data.pdf (144KB)

Effectiveness and Safety of Traditional Chinese Medicine in Treating COVID-19: Clinical Evidence from China Dongmei Xing, Zhibin Liu: 2021, 12 (8): 1850-1856 | DOI: 10.14336/AD.2021.0906; PDF (264KB)

The Functional Role of Lipoproteins in Atherosclerosis: Novel Directions for Diagnosis and Targeting Therapy Yongzheng Lu, Xiaolin Cui, Li Zhang, Xu Wang, Yanyan Xu, Zhen Qin, Gangqiong Liu, Qiguang Wang, Kang Tian, Khoon S Lim, Chris J Charles, Jinying Zhang, Junnan Tang: 2022, 13 (2): 491-520 | DOI: 10.14336/AD.2021.0929; PDF (1199KB)

Intestinal Inflammation and Parkinson’s Disease Yu Li, Yuanyuan Chen, Lili Jiang, Jingyu Zhang, Xuhui Tong, Dapeng Chen, Weidong Le: 2021, 12 (8): 2052-2068 | DOI: 10.14336/AD.2021.0418; PDF (1013KB)

Cover Illustration

26 January 2023. VOL 14, ISSUE 1
The infarct volume assessed by means of MRI in MCAO cynomolgus monkeys. (A) The brain lesions (highlighted area) were detected by MRI at different time points after M1 MCAO.

[Detail]

Cover Illustration

The infarct volume assessed by means of MRI in MCAO cynomolgus monkeys. (A) The brain lesions (highlighted area) were detected by MRI at different time points after M1 MCAO.