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2020
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Total 40 results are found
Rapidly Progressive Dementia with Asymmetric Rigidity Following ChAdOx1 nCoV-19 Vaccination
Sankha Shubhra Chakrabarti, Ashutosh Tiwari, Sumit Jaiswal, Upinder Kaur, Ishan Kumar, Amit Mittal, Anup Singh, Kunlin Jin, Sasanka Chakrabarti
2022, 13 (3): 633-636 | DOI: 10.14336/AD.2021.1102
DeepMAge: A Methylation Aging Clock Developed with Deep Learning
Fedor Galkin, Polina Mamoshina, Kirill Kochetov, Denis Sidorenko, Alex Zhavoronkov
2021, 12 (5): 1252-1262 | DOI: 10.14336/AD.2020.1202
Supplement

1. Supplementary data.pdf (2088KB)

Metabolic Strategies in Healthcare: A New Era
Matthew CL Phillips
2022, 13 (3): 655-672 | DOI: 10.14336/AD.2021.1018
New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases
Yu-Qing Ni, You-Shuo Liu
2021, 12 (8): 1948-1963 | DOI: 10.14336/AD.2021.0603
Comparative Analysis of Aducanumab, Zagotenemab and Pioglitazone as Targeted Treatment Strategies for Alzheimer’s Disease
Morteza Abyadeh, Vivek Gupta, Veer Gupta, Nitin Chitranshi, Yunqi Wu, Ardeshir Amirkhani, Anna Meyfour, Samran Sheriff, Ting Shen, Kunal Dhiman, Ghasem H. Salekdeh, Paul A. Haynes, Stuart L. Graham, Mehdi Mirzaei
2021, 12 (8): 1964-1976 | DOI: 10.14336/AD.2021.0719
Premature Senescence of T-cells Favors Bone Loss During Osteolytic Diseases. A New Concern in the Osteoimmunology Arena
Luis González-Osuna, Alfredo Sierra-Cristancho, Carolina Rojas, Emilio A Cafferata, Samanta Melgar-Rodríguez, Angélica M Cárdenas, Rolando Vernal
2021, 12 (5): 1150-1161 | DOI: 10.14336/AD.2021.0110
Exercise in Aging: Be Balanced
Joanna Gronek, Michał Boraczyński, Piotr Gronek, Dariusz Wieliński, Jacek Tarnas, Sławomir Marszałek, Yi-Yuan Tang
2021, 12 (5): 1140-1149 | DOI: 10.14336/AD.2021.0107
Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal
Alba M Garcia-Serrano, Adélaïde A Mohr, Juliette Philippe, Cecilia Skoug, Peter Spégel, João M.N Duarte
2022, 13 (1): 267-283 | DOI: 10.14336/AD.2021.0720
Supplement

1. Supplementary data.pdf (119KB)

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors
Jing She, Rui Sheng, Zheng-Hong Qin
2021, 12 (8): 1879-1897 | DOI: 10.14336/AD.2021.0523
Depression and Dementia in Older Adults: A Neuropsychological Review
Syuichi Tetsuka
2021, 12 (8): 1920-1934 | DOI: 10.14336/AD.2021.0526
Pharmacological Blockade of NLRP3 Inflammasome/IL-1β-Positive Loop Mitigates Endothelial Cell Senescence and Dysfunction
Alejandra Romero, Pilar Dongil, Inés Valencia, Susana Vallejo, Álvaro San Hipólito-Luengo, Guillermo Díaz-Araya, José L Bartha, María M González-Arlanzón, Fernando Rivilla, Fernando de la Cuesta, Carlos F Sánchez-Ferrer, Concepción Peiró
2022, 13 (1): 284-297 | DOI: 10.14336/AD.2021.0617
Supplement

1. Supplementary data.pdf (503KB)

Polyphenols Could Prevent SARS-CoV-2 Infection by Modulating the Expression of miRNAs in the Host Cells
Dragan Milenkovic, Tatjana Ruskovska, Ana Rodriguez-Mateos, Christian Heiss
2021, 12 (5): 1169-1182 | DOI: 10.14336/AD.2021.0223
The Effect of COVID-19-related Lockdowns on Diet and Physical Activity in Older Adults: A Systematic Review
Elisabeth Anne Larson, Karlen Stade Bader-Larsen, Faidon Magkos
2021, 12 (8): 1935-1947 | DOI: 10.14336/AD.2021.0606
The Proper Diet and Regular Physical Activity Slow Down the Development of Parkinson Disease
Patryk Andrzej Chromiec, Zofia Kinga Urbaś, Martyna Jacko, Jan Jacek Kaczor
2021, 12 (7): 1605-1623 | DOI: 10.14336/AD.2021.0123
The Role of SGLT2 Inhibitors in Vascular Aging
Le Liu, Yu-Qing Ni, Jun-Kun Zhan, You-Shuo Liu
2021, 12 (5): 1323-1336 | DOI: 10.14336/AD.2020.1229
cGAS- Stimulator of Interferon Genes Signaling in Central Nervous System Disorders
Fengjuan Li, Ningqun Wang, Yangmin Zheng, Yumin Luo, Yongbo Zhang
2021, 12 (7): 1658-1674 | DOI: 10.14336/AD.2021.0304
A Unique Type of Highly-Activated Microglia Evoking Brain Inflammation via Mif/Cd74 Signaling Axis in Aged Mice
Chenghao Jin, Yijie Shao, Xiaotao Zhang, Jiani Xiang, Ruize Zhang, Zeyu Sun, Shuhao Mei, Jingyi Zhou, Jianmin Zhang, Ligen Shi
2021, 12 (8): 2125-2139 | DOI: 10.14336/AD.2021.0520
Supplement

1. Supplementary data.pdf (1992KB)

Targeting NLRP3 Inflammasome in the Treatment Of Diabetes and Diabetic Complications: Role of Natural Compounds from Herbal Medicine
Ying Bai, Qianqian Mu, Xueli Bao, Jiacheng Zuo, Xin Fang, Jing Hua, Dongwei Zhang, Guangjian Jiang, Ping Li, Sihua Gao, Dandan Zhao
2021, 12 (7): 1587-1604 | DOI: 10.14336/AD.2021.0318
The Cause of Alzheimer’s Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress
Boris Decourt, Gary X D’Souza, Jiong Shi, Aaron Ritter, Jasmin Suazo, Marwan N Sabbagh
2022, 13 (1): 37-60 | DOI: 10.14336/AD.2021.0529
Irreversibility of Pulmonary Fibrosis
Qing Yang Yu, Xiao Xiao Tang
2022, 13 (1): 73-86 | DOI: 10.14336/AD.2021.0730
tRNA-derived fragments as New Hallmarks of Aging and Age-related Diseases
Ya Yuan, Jiamei Li, Zhi He, Xiaolan Fan, Xueping Mao, Mingyao Yang, Deying Yang
2021, 12 (5): 1304-1322 | DOI: 10.14336/AD.2021.0115
Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy
Satoshi Muraoka, Annina M DeLeo, Zijian Yang, Harutsugu Tatebe, Kayo Yukawa-Takamatsu, Seiko Ikezu, Takahiko Tokuda, David Issadore, Robert A Stern, Tsuneya Ikezu
2021, 12 (6): 1363-1375 | DOI: 10.14336/AD.2020.0908
Supplement

1. Supplementary data.pdf (1144KB)

Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson’s Disease
Loredana Leggio, Greta Paternò, Silvia Vivarelli, Giovanna G Falzone, Carmela Giachino, Bianca Marchetti, Nunzio Iraci
2021, 12 (6): 1494-1515 | DOI: 10.14336/AD.2021.0527
Aspirin Positively Contributes to Drosophila Intestinal Homeostasis and Delays Aging through Targeting Imd
Yangyang Zhu, Qingshuang Cai, Xianrui Zheng, Lei Liu, Yongzhi Hua, Beibei Du, Guomin Zhao, Jiangliu Yu, Zhao Zhuo, Zhongwen Xie, Shanming Ji
2021, 12 (7): 1821-1834 | DOI: 10.14336/AD.2020.1008
Supplement

1. Supplementary data.pdf (842KB)

The Aged Intestine: Performance and Rejuvenation
Qiwen Wang, Yadong Qi, Weiyi Shen, Jilei Xu, Lan Wang, Shujie Chen, Tongyao Hou, Jianmin Si
2021, 12 (7): 1693-1912 | DOI: 10.14336/AD.2021.0202
Neuroplastic Effect of Exercise Through Astrocytes Activation and Cellular Crosstalk
Fengwu Li, Xiaokun Geng, Ho Jun Yun, Yazeed Haddad, Yuhua Chen, Yuchuan Ding
2021, 12 (7): 1644-1657 | DOI: 10.14336/AD.2021.0325
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration
Hongliang Yu, Xudong Yang, Xian Xiao, Meiqian Xu, Yanlei Yang, Chunling Xue, Xuechun Li, Shihua Wang, Robert Chunhua Zhao
2021, 12 (6): 1423-1437 | DOI: 10.14336/AD.2021.0601
Supplement

1. Supplementary data.pdf (100KB)

Extracellular Vesicles for the Diagnosis and Treatment of Parkinson’s Disease
Raghavendra Upadhya, Ashok K Shetty
2021, 12 (6): 1438-1450 | DOI: 10.14336/AD.2021.0516
Therapeutic Potential of Nucleic Acids when Combined with Extracellular Vesicles
Brian Jurgielewicz, Steven Stice, Yao Yao
2021, 12 (6): 1476-1493 | DOI: 10.14336/AD.2021.0708
Blocking C3d +/GFAP + A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke
Qi Zhang, Chang Liu, Rubing Shi, Shiyi Zhou, Huimin Shan, Lidong Deng, Tingting Chen, Yiyan Guo, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang, Yaohui Tang
2022, 13 (3): 943-959 | DOI: 10.14336/AD.2021.1029
Supplement

1. Supplementary data.pdf (888KB)

MSC-Derived Exosomes can Enhance the Angiogenesis of Human Brain MECs and Show Therapeutic Potential in a Mouse Model of Parkinson's Disease
Chunling Xue, Xuechun Li, Li Ba, Mingjia Zhang, Ying Yang, Yang Gao, Zhao Sun, Qin Han, Robert Chunhua Zhao
2021, 12 (5): 1211-1222 | DOI: 10.14336/AD.2020.1221
Promising Intervention Approaches to Potentially Resolve Neuroinflammation And Steroid Hormones Alterations in Alzheimer’s Disease and Its Neuropsychiatric Symptoms
Catia Scassellati, Antonio Carlo Galoforo, Ciro Esposito, Miriam Ciani, Giovanni Ricevuti, Cristian Bonvicini
2021, 12 (5): 1337-1357 | DOI: 10.14336/AD.2021.0122
Supplement

1. Supplementary data.pdf (290KB)

Intrinsic Capacity in Older Adults: Recent Advances
Yaru Zhou, Lina Ma
2022, 13 (2): 353-359 | DOI: 10.14336/AD.2021.0818
ACE2 and COVID-19 Susceptibility and Severity
Ming Zheng
2022, 13 (2): 360-372 | DOI: 10.14336/AD.2021.0805
Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents
Benson OA Botchway, Favour C Okoye, Yili Chen, William E Arthur, Marong Fang
2022, 13 (1): 87-102 | DOI: 10.14336/AD.2021.0616
Supplement

1. Supplementary data.pdf (157KB)

Extracellular GAPDH Promotes Alzheimer Disease Progression by Enhancing Amyloid-β Aggregation and Cytotoxicity
Vladimir F Lazarev, Magda Tsolaki, Elena R Mikhaylova, Konstantin A Benken, Maxim A Shevtsov, Alina D Nikotina, Mirna Lechpammer, Vladimir A Mitkevich, Alexander A Makarov, Alexey A Moskalev, Sergey A Kozin, Boris A Margulis, Irina V Guzhova, Evgeny Nudler
2021, 12 (5): 1223-1237 | DOI: 10.14336/AD.2020.1230
Supplement

1. Supplementary data.pdf (493KB)

Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles
Satoshi Muraoka, Weiwei Lin, Kayo Takamatsu-Yukawa, Jianqiao Hu, Seiko Ikezu, Michael A DeTure, Dennis W Dickson, Andrew Emili, Tsuneya Ikezu
2021, 12 (6): 1376-1388 | DOI: 10.14336/AD.2020.1007
Supplement

1. Supplementary data.pdf (1478KB)

Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells
Chiara de Lucia, Tytus Murphy, Aleksandra Maruszak, Paul Wright, Timothy R Powell, Naomi Hartopp, Simone de Jong, Michael J O'Sullivan, Gerome Breen, Jack Price, Simon Lovestone, Sandrine Thuret
2021, 12 (8): 2151-2172 | DOI: 10.14336/AD.2021.0409
Supplement

1. Supplementary data.pdf (1416KB)

Regulatory T cells in COVID-19
Huan Wang, Zhao Wang, Wen Cao, Qianqian Wu, Yujia Yuan, Xiangjian Zhang
2021, 12 (7): 1545-1553 | DOI: 10.14336/AD.2021.0709
Cellular Senescence in Cardiovascular Diseases: A Systematic Review
Can Hu, Xin Zhang, Teng Teng, Zhen-Guo Ma, Qi-Zhu Tang
2022, 13 (1): 103-128 | DOI: 10.14336/AD.2021.0927